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German nurse gets life in jail after murdering 10 to reduce workload

A palliative care nurse in Germany has been sentenced to life in prison after he was convicted of the murder of 10 patients and the attempted murder of 27 others.

Prosecutors alleged that the man, who has not been publicly named, injected his mostly elderly patients with painkillers or sedatives in an effort to ease his workload during shifts overnight.

The offences were committed between December 2023 and May 2024 in a hospital in Wuerselen, in western Germany.

Investigators are reported to be looking into several other suspicious cases during his career.

According to media outlet Agence France-Presse (AFP), the unnamed man had been employed at the hospital in Wuerselen since 2020, after completing training as a nursing professional in 2007.

Prosecutors told a court in Aachen that he showed "irritation" and a lack of empathy to patients who required a higher level of care, and accused him of playing "master of life and death".

The court was told that he injected patients with large doses of morphine and midazolam, a type of sedative, in an effort to reduce his workload during night shifts.

When issuing the life sentence, the court said that the man's crimes carried a "particular severity of guilt" which should bar him from early release after 15 years.

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Source: BBC News, 6 November 2025

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The unsolved murder on a hospital ward that shames the NHS

Valerie Kneale was chatting away, sitting upright in her hospital bed, when her family left her behind on the ward.

Hours before, the 75-year-old grandmother had been admitted to Blackpool Victoria Hospital in Lancashire in November 2018 after suffering a stroke while eating her dinner.

But she appeared to have made a remarkable recovery. Her husband and two children were assured by hospital staff that they could go home and she would be looked after overnight.

The next morning, Mrs Kneale’s family returned to discover that she had slipped into a coma. She died three days later.

The post-mortem examination revealed that she had been sexually assaulted while on the ward, where entry was controlled by key card, with such force that it had caused severe, fatal blood loss.

Lancashire Constabulary immediately started a murder investigation but seven years on, the force has stopped searching for who was responsible for attacking Mrs Kneale.

Her death – and the failure to find a culprit – is but one tragedy in a hospital that appears to be out of control.

A weeks-long Telegraph investigation has uncovered a litany of failures at Blackpool Victoria:

  • Eight other deaths on the stroke ward in 2018 are being investigated,
  • “Corrupt” nurses were jailed for drugging patients to keep them compliant,
  • Powerful medicines went missing,
  • A heart surgeon was imprisoned for groping the breasts and bottoms of female colleagues,
  • Doctors shared sexist jokes in WhatsApp groups called “cardiac sluts” and “work slags”.

With no one held accountable for the deaths and a police investigation into corporate failings at the stroke unit still ongoing after two years, the families of several victims told The Telegraph that only a public inquiry could answer their questions.

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Source: The Telegraph, 6 November 2025

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Patients told to test at home to free up NHS hospital appointments

Patients across England are set to gain direct access to specialist care via the NHS App, as dozens of new pilot schemes aim to streamline healthcare and ease pressure on hospitals.

This initiative, encompassing 45 pilots across 37 trusts, is projected by the government to free up 500,000 hospital appointments annually once fully implemented.

Officials believe allowing patients to self-report vital health data, such as blood pressure and oxygen levels, through technology could significantly reduce strain on the health service, particularly ahead of winter.

The schemes will primarily focus on five key specialisms: ear, nose, and throat (ENT), gastroenterology, respiratory medicine, urology, and cardiology.

Patients will utilise the NHS App to complete necessary forms and questionnaires, negating the need for in-person hospital visits.

This expansion of remote care coincides with a world-first NHS trial exploring remote support for motor neurone disease patients.

Health Secretary Wes Streeting said: “Patients expect care fit for the 21st century and that’s what I’m determined to deliver.

“This is a government that puts the NHS and patients first as our record investment in the service shows.

“Using tech to bring care closer to home frees up hospital appointments for those who truly need them and makes life simpler for everyone.

“That’s our mission: care that’s easier, faster, and always within reach."

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Source: The Independent, 7 November 2025

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Call to give UK cancer patients legal right to be treated within two months

Cancer patients should have the legal right to be treated within two months, even if that means the NHS has to pay for them to be treated privately or abroad, according to international experts.

Writing in the Lancet Oncology, they say cancer patients should have the legally enforceable entitlement to be treated within 62 days of an urgent referral by a GP.

This would bring the UK in line with Denmark, where cancer patients already have a statutory right to timely treatment.

International research shows that every four weeks of delay in cancer treatment increases the risk of death by up to 10%. But the NHS has not met its target for 85% of cancer patients to start treatment within 62 days since December 2015.

he authors argue that without legal rights in the UK, the government’s forthcoming national cancer plan risks being a paper exercise that will fail to get the UK off the bottom of cancer survival league tables.

“The concern is that the [cancer plan] will be a consensus plan to appease multiple stakeholders, rather than to provide radical, accountable, independent leadership,” the Lancet paper concludes.

Statutory rights to timely treatment would cut waiting lists and improve survival rates, the experts argue. Eduardo Pisani, a co-author of the paper and chief executive of All.Can, a global nonprofit that aims to improve cancer care efficiency, said: “International evidence shows that strong cancer plans, supported by legal rights, ensure patients have guaranteed access to timely, high-quality care. This protection promotes early treatment, reduces inequalities and ultimately improves health outcomes.”

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Source: The Guardian, 6 November 2025

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Scotland: Ministers to order investigation into maternity services

A national investigation into maternity services in Scotland is to be carried out, the BBC understands.

Ministers have indicated that the review will happen when an expert health group assesses how best to conduct it.

It comes after a BBC Disclosure investigation heard calls from families, NHS staff and experts for urgent action to improve maternity safety across the country.

Parents featured in the documentary who lost their babies in Scottish hospitals had demanded an inquiry into maternity services.

Following a damning report into maternity care at the Royal Infirmary of Edinburgh, one of the busiest maternity units in the UK, the Scottish government announced last week that it would set up an expert maternity and neonatal taskforce.

Health Secretary Neil Gray, who revealed that he "nearly lost" his wife during pregnancy after "inaccurate assessments", said the taskforce would listen to "women's experiences of maternity services" and also "the voice of frontline midwives".

Following pressure from bereaved parents, MSPs and health experts, ministers have since confirmed that the taskforce will consider the scope of a national review and examine whether to look into problems with culture alongside the design and delivery of services.

The government confirmed that commitment after a Labour debate at Holyrood calling for a national investigation, with families featured in the Disclosure documentary attending parliament.

Scottish Labour deputy leader Jackie Baillie said: "The heartbreaking truth is too many women and babies are being let down by dangerously overstretched maternity and neonatal services."

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Source: BBC News, 6 November 2025

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Maternity inquiry must include care culture

The father of a baby girl who died five days after she was born in a Leeds hospital has said he wants an independent inquiry into maternity services to focus on culture as well as potential negligence.

Freyja Green died in March 2019 after a traumatic birth at St James's University Hospital.

Her father, Damon Green, who is part of a campaign group calling for action over failings in maternity services run by Leeds Teaching Hospitals NHS Trust, said his family had received poor bereavement care following Freyja's death.

While an inquest found no medical negligence, the trust has apologised for the bereavement care Freyja's parents experienced, adding it was "deeply sorry for the tragic loss".

In October, Health Secretary Wes Streeting confirmed there would be an independent inquiry into the trust's maternity units.

Mr Green said he felt the trust was more concerned with protecting its reputation than with bereaved families, and suggested there was a "culture of arrogance".

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Source: BBC News, 6 November 2025

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ADHD services shutting door to new NHS patients as demand soars, BBC finds

Specialist ADHD services for adults in England are stopping taking on new patients as they struggle to cope with demand, a BBC investigation has shown.

The BBC has identified 15 local areas that have closed waiting lists and another 31 that have introduced tighter criteria, making it more difficult to access support.

Reacting to our investigation, Prof Anita Thapar, chair of NHS England's ADHD taskforce, said the findings were "disturbing", adding there were "enormous risks" for patients.

It comes as she publishes her report into the state of ADHD services on Thursday, which recommends an overhaul of the way people are supported.

ADHD - attention deficit hyperactivity disorder - affects the way the brain works and can cause people to act impulsively and become easily distracted.

The taskforce report said it was being under-diagnosed and under-treated and calls for more joint-working across health, education and the criminal justice system to identify people with ADHD.

It said this would require staff to get training and for community NHS staff, such as GPs and pharmacists, to get more involved in supporting people with ADHD. Currently, specialist services take responsibility for this.

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Source: BBC News, 6 November 2025

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Critical incident declared after EPR launch

A hospital trust has declared a critical incident following the launch of its new electronic patient record system.

Nottingham University Hospitals Trust (NUH) went live with the Nervecentre EPR over the weekend but “technical issues” with the rollout have resulted in “prolonged periods of downtime”.

In an email sent to staff and seen by HSJ, the trust said it declared a critical incident on Tuesday as it was experiencing a “prolonged period of sustained pressure” due to high demand and acuity, as well as challenges around staffing, flow and discharge.

This was compounded by the issues with the new EPR, which had led to business continuity plans being enacted.

The trust said: “We know how difficult the issues with [the] EPR are making an already challenging situation, and we are sorry for the impact it is having. Our teams are working tirelessly alongside our EPR provider, Nervecentre, to resolve performance issues as quickly as possible.”

However, the trust added that it “will only return to Nervecentre when we have confidence in the ability of the EPR to handle demand”.

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Source: HSJ, 5 November 2025

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Council to vaccinate child in care after court win

A council has won a High Court battle to vaccinate a baby against her mother's wishes.

Islington Council faced a legal challenge by one of its residents after it arranged for her eight-month-old daughter to receive routine vaccinations while the child was in its care.

The mother, known only as Ms S, had refused the vaccinations out of her belief there was a link between the jabs and autism – a claim science does not support.

At the High Court, Mr Justice McDonald decided that not vaccinating the girl would leave her at risk of childhood disease "at a very young age when she remains vulnerable," and ruled in favour of the local authority.

The baby, known only as P, has been under the north London council's guardianship since February due to concerns that her mother could not meet her or her older siblings' basic care needs.

In July, the council proposed the infant stay with her mother at the family home while under its supervision, until it was decided whether or not she would permanently be taken out of her mother's care.

During this time the mother refused to have her daughter vaccinated.

After the council moved ahead with the appointment out of concern for the child's welfare, Ms S took the local authority to the High Court to try to stop it.

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Source: BBC News, 5 November 2025

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Streeting’s maternity review delayed ‘by doctors strikes’

The “rapid national investigation” into maternity and neonatal services will no longer publish its interim findings this year, claiming its work has been delayed by this month’s resident doctors strike.

The review – headed by former government minister Baroness Valerie Amos – was announced in June and originally intended to finish by the end of this year. This was subsequently revised to producing an interim report in December, followed by a final one in the spring.

It was announced by health and social care secretary Wes Streeting in June after months of pressure from campaigners in various parts of England, many of whom wanted to see a public inquiry.

A letter to families from Baroness Amos, sent yesterday and seen by HSJ, says: “I will now provide an update on the investigation in December. I plan to give my initial reflections on what I have heard so far; outline plans for the next phase of the investigation, which will include the expected timeframe for publishing my initial findings; and publish the methodology for the investigation, which you have provided helpful feedback on.”

She concluded: “I understand that changes to the timings for the Call for Evidence and content of the December report will be frustrating for some of you. My priority remains ensuring that families’ voices are heard throughout the investigation.”

One bereaved parent said: “It is worrying, both that the timescales are moving out and that the review aims to be finalised so soon after the call for evidence is released.”

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Source: HSJ, 5 November 2025

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Critical incident ongoing at Nottingham hospitals

Nottingham University Hospitals NHS Trust (NUH) has confirmed a critical incident is ongoing due to "sustained pressures" across the organisation.

NUH, which runs both the Queen's Medical Centre and City Hospital, said its emergency department was especially under strain.

The critical incident was declared just after 16:00 GMT on Tuesday after the trust said there were 24 ambulances waiting outside A&E and "large numbers" of people in the department.

The trust, which is one of the busiest in the country, said there had been issues with the technical roll-out of a new electronic patient record system which had added to the ability to manage the current levels of pressure.

Andrew Hall, chief operating officer at NUH, said: "Our staff are working tirelessly to care for patients, but the pressure on our services is causing very long waits and this is causing overcrowding in our emergency department.

"We know how frustrating this will be to people waiting in the department. Our staff are working as hard as they possibly can to get to them as soon as possible."

"Our aim is to prioritise patients with the highest level of need and ensure that we continue to manage emergency care."

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Source: BBC News, 4 November 2025

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Babies born to black mothers 81% more likely to die in neonatal care, NHS study shows

Babies born to black mothers in England and Wales and those from the most deprived areas are significantly more likely to die while in neonatal units, according to analysis revealing the “deeply concerning” figures.

The study, led by academics at the University of Liverpool, examined data on more than 700,000 babies admitted to an NHS neonatal unit across England and Wales between 2012 and 2022.

Babies born to black mothers had the highest mortality rates for the majority of years in the study, with an 81% higher risk of dying before discharge compared with babies born to white mothers.

The highest mortality rate for black babies stood at 29.7 deaths per 1,000 babies, with the highest rate for white babies at 16.9 deaths per 1,000 babies.

For babies born to mothers living in the most deprived areas of England and Wales, the elevated risk stood at 63% compared with the least deprived babies.

The highest mortality rate for babies born to the most deprived mothers was 25.9 deaths per 1,000 babies in 2022, compared with 12.8 deaths per 1,000 for their least deprived counterparts.

Samira Saberian, a PhD student at the University of Liverpool and the lead author of the study, said the analysis showed that “socioeconomic and ethnic inequalities independently shape survival in neonatal units, and maternal and birth factors explain only over half of the socioeconomic and ethnic inequalities”.

She added: “To reduce these inequalities, we need integrated approaches that strengthen clinical care while also tackling the wider conditions affecting families.

“By improving services and addressing the root drivers of inequality, we can give the most vulnerable babies a better chance of survival.”

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Source: The Guardian, 4 November 2025

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Trust’s missing training contributed to death

A coroner has warned a trust over communication failures, leadership and a “lack of professional curiosity” in relation to a patient’s death, which appear to echo previous cases at the provider.

Hampshire and Isle of Wight Healthcare Foundation Trust was criticised by area coroner Nicholas Walker after the death of 34-year-old Abigail Jelley, who took her own life last year while suffering from post-natal depression.

Mr Walker said he was concerned “structural issues with the leadership of [the trust]” could result in harm done to future patients.

He referred to an internal investigation report that he said described a “lack of professional curiosity, lack of escalations of deteriorating patients, non-patient centred decision making and a linear approach to risk assessment and formulation”.

The coroner described how Ms Jelley, who began to struggle with her mental health after the birth of her second child in 2024, was seen by different mental health professionals “whose job it was to react to that crisis and attempt to assist her through it”.

Ms Jelley had been living with her parents before she died, who could have provided valuable information, but they were not spoken to by medical professionals, the coroner said. 

He noted: “It was accepted [by the trust] that there was a lack of professional curiosity shown by professionals both in Abigail’s case and generally.”

It was also found that community mental health teams do not receive mandatory training on perinatal “red flags”, and despite requesting it longer than a year ago, the team had yet to receive it. 

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Source: HSJ, 5 November 2025

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The US might lose its longstanding ‘measles elimination’ status

America may be on track to losing its longstanding measles “elimination status,” held by the United States since 2000.

The status indicates that there has not been continuous spread of the infectious disease for more than a year – but vaccine hesitancy and other factors have sent infections rocketing to their highest levels in 25 years.

There have been 1,648 cases and three deaths tied to the virus this year so far, according to Centers for Disease Control and Prevention data.

And if recent cases, reported in South Carolina or Utah, are tied back to a deadly West Texas outbreak that started in January and health authorities can’t bring the areas under control before the new year, the country’s elimination status is at risk.

In South Carolina, the outbreak fuelled by exposures at Spartanburg County elementary schools has grown to 37 cases, including many unvaccinated students. Utah has seen 64 cases largely around the Southwest, 61 of whom were unvaccinated.

The measles-mumps-rubella vaccine is 97% effective against infection. That’s how the U.S. reached its elimination status initially.

However, child vaccination rates have fallen across the U.S. since before the pandemic, with fewer than 92.5 percent of kindergarteners getting a measles shot for this 2024-2025 school year. Doctors say falling rates are tied to increasing vaccine hesitancy and the spread of misinformation about vaccine safety.

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Source: The Independent, 4 November 2025

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‘Serious leadership failures’ found at major trust

A major trust has been accused of presiding over “serious and systemic failures in leadership” and rated inadequate in the well led domain by the Care Quality Commission. 

Mid and South Essex Foundation Trust, which was previously rated “requires improvement” in 2022 for the leadership domain, said it accepted the regulator’s findings.   

The CQC said: “Many described a culture where poor behaviours went unchallenged, and where financial pressures were perceived to take priority over quality and safety.

“Staff across all three hospital sites told us they felt disconnected from senior leaders, undervalued, and unable to raise concerns without fear.”   

However, the report, which followed an inspection in May, also said leaders had demonstrated “integrity and compassion” and “the scale of the challenge facing the trust required continued energy, enthusiasm, and tenacity”. 

It added: “The assessment team noted signs of fatigue and pressure, which may impact leaders’ ability to lead effectively during a period of significant organisational change.” 

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Source: HSJ, 5 November 2025

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‘A national scandal’: Hundreds of victims of cancer-linked pregnancy drug call for public inquiry

At aged 50, Susie Martin has already undergone her fair share of health procedures. She has endured dozens of surgeries - once going through five procedures in a single year - and will need to have screening for the rest of her life.

She believes it’s all because of a drug her mother was given by medics during pregnancy.

Ms Martin is one of the hundreds of victims of a “silent scandal” involving the pregnancy drug diethylstilbestrol - a synthetic form of the female hormone oestrogen, commonly known as DES, which has been linked to cancer. Like many others, she says the drug, also known as DES, caused her to develop a lifelong gynaecological condition. She now lives in fear for her health, facing tests each year to ensure she hasn’t developed cancer.

A campaign group of more than 300 people, including Ms Martin and her mother Jennifer Bradley, is calling on the government to launch a public inquiry to address what it describes as a national scandal.

Clare Fletcher, partner at the Broudie Jackson Canter solicitors, which represents the group, said: “This is the silent scandal, with victims suffering in pain for decades with limited medical support and no government recognition for what they have been through.

“It is one of the most devastating pharmaceutical failures in UK history and the people whose lives have been marred by it deserve answers.”

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Source: The Independent, 4 November 2025

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‘It’s like the NHS would rather pay a hospital bill over a cheap jab’

Independent readers expressed frustration and disbelief over the government’s decision to restrict free Covid booster jabs to a smaller group of people, describing the move as “a national scandal”.

Many shared stories of being denied the vaccine despite chronic or respiratory illnesses, saying the policy risks leaving vulnerable people like Ella Halpern-Matthews – who has caught Covid three times since losing eligibility – without adequate protection.

Several said they had been forced to pay privately for the jab, effectively creating what they saw as a two-tier health system.

One reader remarked that it felt “as if the NHS would rather pay the hospital bill than for a cheap jab”, while others highlighted the inconsistency of vaccinating care home residents but not staff, and the false economy of cutting the rollout.

Some questioned why countries such as France and Germany continue to offer free or low-cost boosters to wider groups, while the UK “quietly withdrew” access.

Overall, readers urged the government to review eligibility urgently – calling for clearer communication, fairer access, and stronger protection for those still at risk.

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Source: The Independent, 3 November 2025

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Women must be warned of home birth risks and have access to skilled

Women must be given clearer warnings on the potentially fatal dangers of giving birth at home and should only be aided by experienced midwives, experts have said.

Maternity services worldwide are dealing with an increase in the number of women with more complex pregnancies. Many are choosing to have their baby in a familiar environment, in the comfort and privacy of their own home. Some choose a home birth because having their first baby in hospital was “deeply traumatic” and they are reluctant to repeat the experience.

But access to safe, reliable and unrestricted home birth services is patchy, and varies enormously depending on where you live, experts say. Healthcare services in lots of countries struggle to offer home birth services because of staffing shortages, inconsistent training or local policy limitations. Some have dedicated home birth teams, while others rely on overstretched community staff.

The Guardian has spoken to leading doctors, academics and pregnancy experts about home births after a coroner’s court in Rochdale, England, ruled that a mother and daughter died following a home birth owing to “a gross failure to provide basic medical care”.

Jennifer Cahill, 34, died at North Manchester general hospital hours after suffering a haemorrhage while giving birth at home in Prestwich on 3 June 2024. Her baby, Agnes Lily, was delivered not breathing, with the umbilical cord wrapped around her neck. She died at the same hospital as her mother a few days later.

In England and Wales, about one in 50 births take place at home. However, they are recommended only for low-risk pregnancies. Cahill’s pregnancy was considered high-risk because she had suffered a postpartum haemorrhage after giving birth to her first child in 2021.

Because of this, she was advised to have her second baby in hospital. But her husband, Rob, told the court the dangers of a home birth had not been fully explained. Phrases such as “out of guidance” were favoured, rather than “against medical advice”, and the risk of death was not explicitly raised, the inquest was told.

“This is an unbearably sad case of two avoidable deaths,” said Kim Thomas, chief executive of the Birth Trauma Association, one of the first charities in the world to support women and families who have experienced traumatic births. “We often hear from women who, having had a deeply traumatic first birth in hospital, are reluctant to give birth in hospital again. Some choose not to have another baby, while others opt for home birth.

“Unfortunately, for women like Jennifer Cahill, who had experienced numerous complications in her previous birth, a home birth can be particularly risky. Several things seem to have gone wrong in this case. It seems staff were reluctant to spell out the risks to Mrs Cahill, so she was not able to make a fully informed decision.”

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Source: The Guardian, 4 November 2025

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Hundreds of lung cancer patients harmed after long waits

Hundreds of lung cancer patients are coming to harm while waiting longer than the 62-day benchmark for starting treatment, according to unpublished data collated by HSJ which ministers have called “shocking”.

The figures, obtained from Freedom of Information requests, also suggest the true figure could be even higher, because around 30% of the 104 relevant trusts did not provide data. A leading expert also warned the findings were likely “a conservative estimate” of the level of harm.

The figures are understood to represent the first time the number of harm reviews relating to lung cancer patient long waits across all English trusts has been quantified.

The findings come as scrutiny around the NHS’s record on cancer is set to intensify in the coming months, with the government set to publish a new National Cancer Plan.

Lung cancer is the leading cause of cancer death in the UK, which has some of the worst survival rates in Europe for the condition, with only about 10 per cent of patients living longer than 10 years. There are around 49,300 cases of lung cancer diagnosed in the UK each year, accounting for 13 per cent of all new cancers.

The 71 responding trusts contacted by HSJ revealed they had carried out 4,574 harm reviews following lung cancer patients breaching the constitutional 62-day target for starting treatment in the two years between 1 January 2023 and 31 December 2024.

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Source: HSJ, 4 November 2025

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Patient safety concerns must be raised and acted on, GMC warns as it launches review of key guidance

Doctors, physician associates (PAs) and anaesthesia associates (AAs) must speak up if they spot patient safety concerns, and healthcare leaders must act when issues are raised with them, the General Medical Council (GMC) says as it launches a review of key guidance.

The GMC is seeking views on two pieces of its guidance, Raising and acting on concerns about patient safety and Leadership and management. Both pieces of guidance play crucial roles in setting positive workplace culture standards that prioritise patient safety. They make clear the regulator’s expectations on when and how concerns should be raised, as well as how those in management positions should respond.

The regulator is ensuring the guidance reflects developments across the UK’s healthcare systems, and wider social changes, while remaining clear, relevant and helpful. It will be the first significant updates since they were published in 2012.

Earlier this year results from the GMC’s annual national training survey revealed that more than one in five trainee doctors were hesitant about escalating concerns about patient care, and GMC Chief Executive Charlie Massey warned, in a speech in September, that maternity services were at risk from harmful cultures that put ‘cover-up over candour’ and ‘obfuscation over honesty’.

Professor Pushpinder Mangat, Medical Director and Director of Education and Standards at the GMC, said:

"Our guidance is there to provide support and confidence, as well as practical help, for people to speak up when necessary. But speaking up is no good in isolation. Leaders and managers have a duty to act when concerns are raised with them.

‘Whenever we update guidance, it is important we hear views from a range of respondents. Their voices and real-life experiences will be instrumental in ensuring our guidance is clear, relevant, and helpful, and reflects the needs of everyone it affects."

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Source: GMC, 3 November 2025

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USA: Doctors issue warning about ‘autism drug’ endorsed by Trump administration

A drug endorsed by the Donald Trump administration which allegedly treats against a rare disorder that causes autism-like symptoms has triggered a surge in demand from parents, despite a lack of data supporting its use.

More parents in the U.S. are asking for leucovorin, believing it could unlock speech and social connection in their autistic children.

Paediatricians and specialists caution the science on leucovorin in autistic people as the data is limited and does not support widespread use.

In the month since Food and Drug Administration Commissioner Marty Makary promoted the decades-old drug from GSK, saying it could help hundreds of thousands of autistic children, doctors and researchers say they have been inundated by parents seeking information.

“My Facebook feed is flooded with parents swearing that leucovorin works,” said Dr. David Mandell, a professor of psychiatry and autism researcher at the University of Pennsylvania.

Mandell and other scientists and doctors say Trump’s endorsement, without requiring large, randomized clinical trials, leaves practitioners facing emotional pleas from families while lacking data, guidance or confidence to prescribe the drug responsibly.

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Source: The Guardian, 1 November 2025

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MHRA calls on public to report side effects and suspected fakes during #MedSafetyWeek

The Medicines and Healthcare products Regulatory Agency (MHRA) is urging the public to help keep medicines, medical devices, vaccines and blood products safe by reporting any side effects, device incidents and suspected fake medical products, as part of #MedSafetyWeek (3–9 November).  

The global campaign is marking its tenth year, bringing together more than 130 regulators and health organisations across 117 countries with one shared message: everyone has a role to play in medicine safety. 

Reporting matters more than ever 

With more people using medicines and medical devices than ever before – from weight loss treatments to wearable monitors – safety reporting is a key part of protecting public health.  

An estimated 2.5 million people in the UK are now using weight loss medicines, many bought online and delivered by post. Thousands use glucose sensors or blood-pressure monitors in the comfort of their own homes. As medicines and medical devices play a bigger role in daily life, including to prevent illness rather than treat it, public reporting of safety concerns is more important than ever. 

Professor Anthony Harnden, MHRA Chair, said:  

“Healthcare has changed significantly over the past decade, alongside advances in science and technology. Medicines and medical devices are part of everyday life for millions of people, and many are accessed in new ways, including online.  

“If you experience a side effect, notice a device isn’t working properly, or suspect a fake medical product, please tell us via the MHRA’s Yellow Card scheme. Your report could protect others – and it only takes minutes.” 

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Source: MHRA, 3 November 2025

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NHS trials AI prostate cancer tool that could ‘massively improve’ treatment

A new study is set to investigate how AI could significantly improve doctors’ decisions regarding prostate cancer treatment.

While diagnostic methods for the disease have become safer and more precise, medical professionals still face considerable challenges in accurately assessing its aggressiveness in individual patients.

This difficulty can lead to some men undergoing invasive procedures such as surgery or radiotherapy, when a less aggressive monitoring approach might have been more appropriate.

The crucial Vanguard Path study, spearheaded by researchers at the University of Oxford, is being funded with a £1.9m grant from the charity Prostate Cancer UK to address this vital issue.

Experts will first test the technology – called ArteraAI Prostate Biopsy Assay – on prostate biopsy samples from men who have already been diagnosed and treated for the disease and have at least five years of follow-up data.

The study will compare how well the predictions made by the AI tool match what happened to patients in the real world.

It will then be tested in real clinics on biopsies from men as they are diagnosed, with a focus on cases in which doctors find it hard to decide the best course of treatment.

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Source: The Independent, 3 November 2025

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Thousands of poorest Scots to receive free weight-loss jabs in trial

Thousands of people from some of Scotland's most deprived areas are to be offered free weight-loss jabs as part of government-funded research.

Up to 5,000 people in Scotland will take the injections as part of the multi-million pound study being led by Glasgow University.

The findings will provide insight into the lives of people living with obesity and health inequalities across the UK.

If successful, it could lead to a wider rollout of the injections throughout the country.

The UK government has provided an initial £650,000 for the Scotland CardioMetabolic Impact Study (SCoMIS).

As a leading cause of long-term illness such as heart disease and cancer, tackling obesity will help millions live longer healthier lives and reduce the pressure on health services, potentially saving the NHS billions annually.

UK Health Innovation Minister Dr Zubir Ahmed said: "As a practicing NHS surgeon and Glasgow MP, I know firsthand the impact of the obesity crisis that plagues Scotland – and the litany of health problems it leads to.

"More than 1 in 3 adults in Scotland's most deprived areas are living with obesity. The UK government is committed to tackling inequality wherever it finds it in our country.

"It's why this landmark UK government investment is targeting help where it's needed most in Scotland and meeting people where they are and backing helping the NHS services they trust to treat them."

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Source: BBC News, 1 November 2025

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‘Everything is either anxiety or your period’: Readers share experiences of being dismissed by NHS GPs

Too often, young people with serious illnesses are dismissed or told they’re “too young” to be sick – and Independent readers have been sharing their own experiences of being ignored by the NHS.

Readers shared experiences of being dismissed by healthcare professionals, and speculated whether that was down to age, gender, or assumptions about their symptoms.

One reader’s story mirrored the challenges faced by patients like 19-year-old Milli Tanner, who went to 13 GP appointments and A&E visits over two years before being diagnosed with stage 3 bowel cancer. She was initially told her symptoms were caused by piles, IBS, or her age, and faced long waits for urgent testing before finally receiving a diagnosis.

Readers highlighted the emotional and physical toll of such dismissal, with one sharing being misdiagnosed for three years despite a private MRI showing multiple active MS lesions.

Another described how a family’s Lynch Syndrome history was overlooked, contributing to preventable deaths from bowel and uterine cancer.

Overall, Independent readers stressed that listening, taking symptoms seriously, and empowering patients are crucial to prevent young people from being failed by the system.

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Source: The Independent, 2 November 2025

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