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New MHRA rules for treatment with isotretinoin

Treatment with isotretinoin for UK patients under 18 years of age must be approved by two prescribers in a series of regulatory changes announced by the Medicines and Healthcare products Regulatory Agency (MHRA) to strengthen the safe use of this drug.

Isotretinoin, also known by the brand names Roaccutane and Reticutan, is an effective treatment for severe acne or when there is a risk of permanent scarring. While the drug has helped many patients with severe acne, concerns have arisen among patients and members of the public regarding suspected mental health side effects, including depression, anxiety, psychotic symptoms, and suicide, as well as sexual side effects.

Following an expert safety review, the Commission on Human Medicines (CHM) agreed in April of this year to a number of recommendations to strengthen the safe use of the treatment.

The safety review concluded that because of gaps in the available evidence, it was not possible to say that isotretinoin definitely caused many of the short-term or long-term mental health and sexual side effects. However, since the individual experiences of patients and families continued to cause concern, the experts recommended that action be taken to ensure patients were made aware of these potential risks and that they were carefully monitored during treatment.

"The overall balance of risks and benefits for isotretinoin remains favourable," the authors of the report concluded, but further action should be taken to ensure patients were fully informed about isotretinoin and were effectively monitored during and after treatment, they recommended.

Anna Rossiter, programme manager for Medicines for Children at the Royal College of Paediatrics and Child Health, said the information for young people and their families "needs to be written in a format that is easy to understand and must set out the possible side effects that might be experienced".

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Source: Medscape, 1 November 2023

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New menopause therapy guidance will harm women’s health, say campaigners

New official guidance on treating menopause will harm women’s health, experts, MPs and campaigners have warned.

Last month, new draft guidelines to GPs from the National Institute for Health and Care Excellence (NICE) said that women experiencing hot flushes, night sweats, depression and sleep problems could be offered cognitive behavioural therapy (CBT) “alongside or as an alternative to” hormone replacement therapy (HRT) to help reduce their menopause symptoms.

But critics have castigated the guidance, saying it belittled symptoms through misogynistic language, and women’s health would suffer as a result of failing to emphasise the benefits of HRT on bone and cardiovascular health as opposed to CBT.

In its response to the guidance, Mumsnet said NICE's recommendations used “patronising” and “offensive” language and would be “detrimental” to women’s health.

Justine Roberts, the founder and chief executive of Mumsnet, said: “Women already struggle to access the HRT they are entitled to. We hear daily from women in perimenopause and menopause who are battling against a toxic combination of entrenched misogyny, misinformation and lack of knowledge among GPs.

“Too often they are fobbed off or told they simply need to put up with severe physical and mental symptoms – often with life-changing effects.

“By emphasising the negative over the positive, failing to include information about the safest forms of HRT and placing CBT on a par with hormone replacement therapy, this guidance will worsen that struggle. It will make doctors more reluctant to prescribe HRT and women more fearful about asking for or accepting it.”

Carolyn Harris, the MP for Swansea East and the chair of the all-party parliamentary group on menopause, said the new guidance was “antiquated”, “naive” and “ill thought-out”.

”Talking can make you feel better, but it’s not going to take away the aches in your joints and it’s not going to change how you live your life,” she said. “Whatever a woman feels is what she needs to support her through the menopause should be readily and immediately available, and that’s not true currently [of HRT or CBT]."

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Source: The Guardian, 11 December 2023

 

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New Marburg outbreaks in Africa raise alarm about the deadly virus’s spread

Two concurrent outbreaks of the Marburg virus, a close cousin of Ebola that can kill as many as 90 percent of the people it infects, are raising critical questions about the behaviour of this mysterious bat-borne pathogen and global efforts to prepare for potential pandemics.

Marburg causes high fever, vomiting, diarrhoea and bleeding from orifices. It spreads between people via direct contact with the blood or other bodily fluids of infected people and with surfaces and materials such as clothing contaminated with these fluids.

One of the two outbreaks, in Tanzania in East Africa, seems to have been brought under control, with just two people left in quarantine. But in the other, in Equatorial Guinea on the west coast, spread of the virus is ongoing, and the World Health Organization (WHO) said last week that the country was not being transparent in reporting cases.

The WHO said both outbreaks pose regional risks: Equatorial Guinea has porous borders with Cameroon and Gabon, and so far the cases have appeared in geographically diffuse parts of the country. In Tanzania, the Kagera region has busy borders with Uganda, Rwanda and Burundi.

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New York Times, 5 April 2023

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New long Covid enhanced service (ES) to pay just under 50p per registered patient

GPs have been given until the 31st July to sign up patients to the new enhanced long Covid enhanced service (ES).

The new service was set up to help support patients with the condition as it was considered complex and needed consistent support. 

The ES is also intended to help GP practices 'plan their workforce set up, training needs and infrastructure in order to support patients with this new condition’. 

The payment to practices will occur on a monthly basis and will be paid 75% of the fee (£0.371) per registered patient. The remaining 25% (£0.124 )will be paid once patients have been signed up. 

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Source: Pulse Today, 21 June 2021

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New legislation to provide for mandatory open disclosure

Hospitals will face penalties if staff do not notify patients of serious adverse incidents under proposed new legislation.

Due to be brought to Cabinet by the Minister for Health Simon Harris in early December, it will provide for mandatory open disclosure of patient safety issues. It is understood that the new Bill would mean that where a hospital or health service provider was satisfied that a notifiable patient safety incident had occurred, information in its possession on the issue should be disclosed. A doctor or practitioner would be obliged to inform the patient and hospital of the incident.

Under the proposals, failure to comply with this requirement on disclosure would mean the health service provider would be penalised. The nature or extent of the proposed penalties is unknown.

The department is preparing a list of notifiable patient safety incidents for the mandatory open disclosure proposals.

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Source: The Irish Times, 25 November 2019

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New Learning and Action Network set to improve maternal and neonatal health outcomes

The NHS Race and Health Observatory, in partnership with the Institute for Healthcare Improvement and supported by the Health Foundation, has established an innovative 15-month, peer-to-peer Learning and Action Network to address the gaps seen in severe maternal morbidity, perinatal mortality and neonatal morbidity between women of different ethnic groups.

Across England, nine NHS Trusts and Integrated Care Systems will participate in this action oriented, fast-paced Learning and Action Network to improve outcomes in maternal and neonatal health. Through the Network, the nine sites will aim to address the gaps seen in severe maternal morbidity, perinatal mortality and neonatal morbidity between women of different ethnic groups. Haemorrhage, preterm birth, post-partum depression and gestational diabetes have been identified as some of the priority areas for the programme.

The sites will generate tailored action plans with the aim of identifying interventions and approaches that reduce health inequalities and enhance anti-racism practices and learning from the programme. These will be evaluated and shared across and between healthcare systems.

The Network, the first of its kind for the NHS, will combine Quality Improvement methods with explicit anti-racism principles to drive clinical transformation, and aims to enable system-wide change.  Over a series of action, learning and coaching sessions, participants will review policies, processes and workforce metrics; share insights and case studies; and engage with mothers, parents, pregnant women and people.

The programme will run until June 2025, supported by an advisory group from the NHS Race and Health Observatory, Institute for Healthcare Improvement, and experts in midwifery, maternal and neonatal medicine.

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Source: NHS Race and Health Observatory, 24 January 2024

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New leaders bring ‘energy, focus and grit’ to troubled trusts, says NHSE

Changing chairs, CEOs and finance chiefs has helped turn around several poorly performing trusts and systems, NHS England has said, but it plans to do more to “strengthen” leadership at troubled organisations.

Dame Emily Lawson made the comments in an update to NHSE’s board on its “recovery support programme”, which is the current name of its intervention regime for the most poorly performing trusts and systems.

The NHSE chief operating officer said: “We know we have got more to do… to strengthen leaders at the most challenged places. We are developing a more systematic way of identifying and developing talented leaders and matching them to roles where they can make the biggest impact when in post.

“That means we need to give leaders the right flexibilities, incentives and support to turn things around.”

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Source: HSJ, 6 December 2024

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New law to dissolve CCGs and curtail the internal market confirmed

The government has confirmed its commitment to bring in new health legislation during this Parliament, but social care reform has again been ‘kicked into the long grass’.

Today’s Queen’s Speech confirmed that planned, radical changes to the Health and Social Care Bill 2012 will be laid before Parliament this year.

The changes, first outlined in the government’s proposals this February, will put integrated care systems on a statutory footing, dissolve clinical commissioning groups, water down the internal market within the NHS and increase the powers the health secretary has over NHS England and the service. 

Today’s Queen’s Speech said these changes meant “patients will receive more tailored and preventative care, closer to home [and will] empower the NHS to innovate and embrace technology”.

However, it did not add any further information to the government’s already stated plans to “bring forward proposals in 2021” for social care reform. The 2019 Queen’s Speech, the first delivered during Boris Johnson’s tenure as prime minister, promised to bring in ”legislation for long-term social care reform in England”. To date, the government has failed to act on this promise.

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Source: HSJ, 11 May 2021

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New Jersey will stockpile abortion pills, governor says before Trump inauguration

New Jersey will begin stockpiling supplies of a key abortion drug, Governor Phil Murphy announced, days before President-elect Donald Trump returns to office with Republican majorities in the House and Senate.

“A couple of years ago, New Jersey worked proactively to protect abortion rights,” Murphy said during his State of the State address on Tuesday, in reference to a law he signed months before the Supreme Court overturned Roe v. Wade in 2022. “And now we must further secure our reputation as a safe haven for reproductive freedom.”

In addition to urging the Democratic-held state legislature to pass a law to “scrap out-of-pocket costs for abortion procedures,” Murphy announced that New Jersey will stockpile abortion medication mifepristone “so every woman can access this crucial form of reproductive care.” The decision, he said, was prompted by “anti-choice policies supported by the current majorities in Congress.”

In November, reproductive-health organizations and companies reported that more women were seeking abortion pills in the aftermath of Trump’s election victory, while antiabortion advocates began planning aggressive legal action against people and organizations that help women get abortions, as The Washington Post reported. As states moved to restrict people’s access to abortion and abortion pills in the wake of Roe’s fall, New Jersey’s abortion protections have ensured that both remain legal there.

In 2023, Democratic governors in other states—including California and Massachusetts—also announced plans to stockpile abortion pills. Eighteen US states now have bans on all or most abortions, three have bans on abortions after 12 or 15 weeks, while courts in two others have blocked similar laws—although thousands of women in states with restrictions are turning to online providers to access abortion pills.

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Source: Washington Post, 16 January 2025

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New jab which could help thousands with rare heart condition approved for NHS use

A new at-home injection has been approved for use on the NHS offering a significant breakthrough for approximately 1,500 individuals in England and Wales living with a rare heart condition.

Vutrisiran will be available for patients suffering from transthyretin amyloidosis with cardiomyopathy (ATTR-CM), a debilitating illness where the liver-produced protein transthyretin misfolds, leading to deposits that stiffen the heart. Without intervention, this progressive condition can tragically culminate in heart failure.

Vutrisiran, sold under the brand name Amvuttra and made by Alnylam Pharmaceuticals, works by binding to, and stifling messenger RNA (mRNA) to reduce the amount of transthyretin made by the liver.

The injection, taken every three months by patients in their own home, has been recommended by Nice as a treatment option for some adults with ATTR-CM.

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Source: The Independent (21 November 2025)

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New IT system harms trust’s cancer performance for six months

A trust which is struggling with a new electronic patient record (EPR) is likely to see cancer performance affected for at least the rest of this year, it has said.

Ashford and St Peter’s Hospitals Foundation Trust has set up eight workstreams to ensure its EPR – supplied by Oracle Cerner – is “functioning safely, efficiently and as effectively as possible” after a host of problems since it went live in May. Cancer areas affected include breast, breast symptomatic two week waits, and dermatology.

“It is expected that the impact of the introduction of SSC [Surrey Safe Care, the name of the project] will be felt in aspects of our cancer performance until at least December 2022,” July’s board meeting was told.

The performance report warned the risk of delays causing harm to cancer patients – currently rated at 12 on the risk register – was being reviewed as a result of the introduction of SSC and was expected to rise. 

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Source: HSJ, 8 August 2022

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New inquiry: NHS Leadership, performance and patient safety

The Health and Social Care Committee has launched a new inquiry to examine leadership, performance and patient safety in the NHS.

Inquiry: NHS leadership, performance and patient safety

MPs will consider the work of the Messenger review (2022) which examined the state of leadership and management in the NHS and social care, and the Kark review (2019) which assessed how effectively the fit and proper persons test prevents unsuitable staff from being redeployed or re-employed in health and social care settings.

The Committee’s inquiry will also consider how effectively leadership supports whistleblowers and what is learnt from patient safety issues.

An ongoing evaluation by the Committee’s Expert Panel on progress by government in meeting recommendations on patient safety will provide further information to the inquiry.

Health and Social Care Committee Chair Steve Brine MP said:

“The role of leadership within the NHS is crucial whether that be a driver of productivity that delivers efficient services for patients and in particular when it comes to patient safety.

Five years ago, Tom Kark QC led a review to ensure that directors in the NHS responsible for quality and safety of care are ‘fit and proper’ to be in their roles. We’ll be questioning what impact that has made.

We’ll also look at recommendations from the Messenger review to strengthen leadership and management and we will ask whether NHS leadership structures provide enough support to whistleblowers.

Our Expert Panel has already begun its work to evaluate government progress on accepted recommendations to improve patient safety so this will build on that. We owe it to those who rely on the NHS – and the tax-payers who pay for it – to know whether the service is well led and those who have been failed on patient safety need to find out whether real change has resulted from promises made.”

Terms of Reference

  • The Committee invites written submissions addressing any, or all, of the following points, but please note that the Committee does not investigate individual cases and will not be pursuing matters on behalf of individuals.  
  • Evidence should be submitted by Friday 8 March. Written evidence can be submitted here of no more than 3,000 words.  
  • How effectively does NHS leadership encourage a culture in which staff feel confident raising patient safety concerns, and what more could be done to support this?
  • What has been the impact of the 2019 Kark Review on leadership in the NHS as it relates to patient safety?
  • What progress has been made to date on recommendations from the 2022 Messenger Review?
  • How effectively have leadership recommendations from previous reviews of patient safety crises been implemented?
  • How could better regulation of health service managers and application of agreed professional standards support improvements in patient safety?
  • How effectively do NHS leadership structures provide a supportive and fair approach to whistleblowers, and how could this be improved?
  • How could investigations into whistleblowing complaints be improved?
  • How effectively does the NHS complaints system prevent patient safety incidents from escalating and what would be the impact of proposed measures to improve patient safety, such as Martha’s Rule?
  • What can the NHS learn from the leadership culture in other safety-critical sectors e.g. aviation, nuclear?

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Source: UK Parliament, 25 January 2024

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New inquiry at Limerick hospital after a second girl dies suddenly aged 16

Another inquiry has been launched into the sudden death of a second teenage girl in the Accident and Emergency department of University Hospital Limerick three weeks ago.

The 16-year-old girl died suddenly on January 29, hours after she was rushed to UHL suffering from breathing difficulties.

The girl, a much-loved only child, died in front of her mother in what an informed source described as “deeply traumatic circumstances”.

It is the latest tragedy under review at UHL following the death of Aoife Johnston (16) from Shannon, Co Clare,

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Source: Irish Independent, 20 February 2024

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New inpatients banned at mental health unit rated unsafe

A privately run mental health unit has been banned from admitting new patients after inspectors found numerous safety failings, one of which led to a resident dying by hanging.

The Care Quality Commission (CQC) has stopped the Cygnet Acer Clinic, in Chesterfield, Derbyshire, from accepting new inpatients. It declared that the facility was “not safe” for people to use.

Inspectors found that clinic patients had opportunities to hang themselves, and the unit had soaring levels of patient self harm, and a huge shortage of trained staff.

The CQC’s report is one of the most damning it has issued about poor and unsafe care affecting vulnerable and potentially suicidal patients in a mental health facility.

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Source: The Guardian, 13 November 2019

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New immersive room in A&E will 'change so many lives'

The parents of an autistic boy say a new immersive room in their local hospital's children's A&E will "change so many lives".

Robert and Gemma Cummings spent the past year fundraising to open the room, which is the first of its kind in Wales, at the paediatric department of Prince Charles Hospital in their hometown of Merthyr Tydfil.

The project was inspired by their own "distressing" experiences with their six-year-old son Ellis, who struggles with "sensory overload".

They hope the room, officially opened on Thursday, will allow children to receive emergency care without parents reaching a "crossroads" in deciding whether or not hospital visits are worth the potential of trauma.

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Source: BBC News, 7 December 2025

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New HSIB investigation looks at medication omission in mental health hospitals

The Healthcare Safety Investigation Branch (HSIB) have started a new national investigation looking into medication omission in mental health hospitals.

It was launched after they were notified by the parent of a young adult service user with a learning disability that he was regularly not offered prescribed medication whilst on a long-stay mental health ward.

The investigation will focus on information transfer within the prescribing and administration of medication in mental health hospitals to reduce omissions.

Follow the progress on the medication omission in mental health hospitals investigation page.

Source: HSIB, 30 September 2019

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New hospitals could be required to have single patient rooms only

New hospitals may be required to have single patient rooms only, HSJ has revealed

Chiefs at the New Hospitals Programme (NHP) are assessing whether to include a requirement for 100% single rooms in the new facilities, in what would be a major change for NHS hospital design.

It comes a year after NHS England medical director Stephen Powis said single patient rooms should be “the default” in hospitals as this would improve infection control and patient flow. Currently, the Department of Health and Social Care expects hospitals to consider a minimum of 50% single rooms when refurbishing or building new sites.

HSJ understands the NHP is working with the NHS’ technical standards team on how many single rooms will be required in the new hospitals the government has committed to building by 2030. The teams are considering recommending the percentage to be raised from 50% to 100%. The work is part of efforts to standardise design across the NHP projects and so therefore better control costs. 

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Source: HSJ, 30 September 2022

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New hospital tech disrupts doctors' and nurses' jobs, forces improvisation to ensure patient safety

Doctors and nurses must adapt their routines and improvise their actions to ensure continued patient safety, and for their roles to be effective and to matter as new technology disrupts their working practices.

Research from Lancaster University Management School, published in the Journal of Information Technology, found electronic patient records brought in to streamline and improve work caused changes in the division of labour and the expected roles of both physicians and nursing staff.

These changes saw disrupted working practices, professional boundaries and professional identities, often requiring complex renegotiations to re-establish these, in order to deliver safe patient care. Managers implementing these systems are often quite unaware of the unintended consequences in their drive for efficiency.

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Source: EurekAlert, 25 November 2019

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New hospital showcases 'different way of working'

When the new Royal Liverpool Hospital opens its doors in October, every patient will have a single room with an en-suite bathroom.

That set-up is unusual for acute hospitals in England, but many feel it is the future for all new buildings.

"There's the privacy and dignity from the patient's point of view," says Jacqui Stamper, the hospital's associate chief nurse. "If they're in the room and talking to the doctors or the nurses, there isn't somebody just the other side of a curtain listening."

"And then there's the infection prevention side of it as well.

"It's absolutely the state of the art way of hospital care really."

The new system will require staff to work differently, so patients can be properly monitored.

Each ward has been broken up into smaller zones of between six and eight beds, and each zone has its own base where the nurses will sit.

The trust which runs the hospital is currently running workshops to get staff used to the layout.

"Nursing staff will be used to working in a bigger team than a couple of people, so it is a different way of working," Ms Stamper says.

"We're listening to our staff and their concerns and answering those to see how we can address them going forward."

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Source: BBC News, 2 September 2022

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New hospital achieves 'outstanding' first

Royal Papworth Hospital in Cambridge, a leading heart hospital, has become the first NHS hospital trust to earn "outstanding" ratings across the board by inspectors.

The hospital earned the top rating across all five tested areas – safety, effectiveness, care, responsiveness and leadership.

The Care Quality Commission (CQC) inspectors said: "A caring culture ran through the trust."

The CQC's Chief Inspector of Hospitals, Prof Ted Baker, said he was "very impressed by the high-quality care and treatment offered".

"Patients received exemplary care from committed and qualified staff," the report concluded.

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Source: BBC News, 16 October 2019

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New HIV protection jab approved for use in Northern Ireland

An injection to prevent HIV which is being offered in Great Britain will also be rolled out in Northern Ireland, it has been confirmed.

The long-acting cabotegravir (CAB-LA) jab, which is administered every two months, is an alternative to HIV prevention pills, known as PrEP, which is used daily.

It was announced last month that the injection had been approved for England and Wales, bringing it into line with Scotland.

Campaigners had called for Northern Ireland health authorities to follow suit - with the Department of Health (DoH) now saying the treatment will be rolled-out, a prominent LGBT charity has described the move as "a game-changer".

The Rainbow Project's chief executive Scott Cuthbertson said it "could make HIV prevention much more widely accessible".

Known as PrEP (pre-exposure prophylaxis), the treatment is taken by HIV-negative people to reduce the risk of getting HIV. It was introduced in Northern Ireland in 2018.

It is taken as a pill and is effective, but they are not always easy for some to take.

It can be hard to access, unpractical or feel embarrassing if people are worried about the possibility of parents or housemates finding the medication.

Other factors such as homelessness can make it difficult to take oral PrEP every day.

However, cabotegravir is given as jab, usually six times a year or every other month, making it potentially more convenient and discreet.

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Source: BBC News, 9 November 2025

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New heart failure drug for thousands of UK patients given go ahead

More than a quarter of a million patients living with heart failure could be eligible for a new drug that reduces deaths and hospitalisation after medical regulators gave it the greenlight.

The National Institute for Health and Care Excellence (Nice) has approved dapagliflozin, made by AstraZeneca, for use on the NHS.

It can help treat patients with a form of chronic heart failure that means their blood does not pump blood out to the body as well as it should.

It is estimated almost one million people are living with heart failure in the UK which causes an estimated 65,000 unplanned hospital admissions a year. Around half of patients will die within five years of being diagnosed.

Evidence from a clinical trial shows that adding dapagliflozin to standard care lowers the risk of dying from heart disease and decreases hospitalisation or an urgent outpatient visit because of heart failure by 26% compared with standard care alone.

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Source: The Independent, 24 December 2020

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New Heart Age Test prevents heart attack and stroke deaths

A new study by Staffordshire University shows that people who understand their ‘heart age’ are more likely to make healthy lifestyle changes.

50 preventable deaths from heart attack or stroke happen every day and Public Health England’s online Heart Age Test (HAT) allows users to compare their real age to the predicted age of their heart.

The tool aims to provide early warning signs of cardiovascular disease (CVD) risk, encouraging members of the public to reduce their heart age through diet and exercise and to take up the offer of an NHS Health Check.

CHAD Research Associate Dr Victoria Riley, who led the study, said: “Deaths from heart attack or stroke are often preventable and so addressing health issues early is incredibly important. Our findings show that pre-screening tests, such as the HAT, can encourage individuals to evaluate their lifestyle choices and increase their intentions to change behaviour.”

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Source: Brigher Side of News, 10 October 2021

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New health secretary named

Sajid Javid has resigned and been replaced by Steve Barclay as health and social care secretary. 

Mr Barclay, previously chief of staff to the prime minister, was reported as having been given the role on Tuesday evening.

Mr Barclay said: “It is an honour to take up the position of Health and Social Care Secretary. Our NHS and social care staff have showed us time and again - throughout the pandemic and beyond - what it means to work with compassion and dedication to transform lives.  This government is investing more than ever before in our NHS and care services to beat the Covid backlogs, recruit 50,000 more nurses, reform social care and ensure patients across the country can access the care they need.” 

Mr Barclay’s appointment came hours after Mr Javid — health secretary since June last year — announced his resignation, saying in a letter to Boris Johnson that he “can no longer, in good conscience, continue serving in this government” and that Mr Johnson has lost his confidence.

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Source: HSJ, 6 July 2022

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New health minister appointed

The government has appointed an MP who has campaigned on patient safety to be the new public health and prevention minister.

MP Sharon Hodgson will replace Ashley Dalton, who has metastatic breast cancer and yesterday announced she is stepping down. Ms Dalton will continue as MP for West Lancashire.

The new minister has campaigned for compensation for women injured by pelvic mesh, telling MPs that her mother was one of those who experienced “life-limiting complications” as a result of the implants.

She chairs a cross-party group of MPs set up to raise awareness of the 2020 Cumberlege review, which called for the appointment of a patient safety commissioner and an overhaul of existing arrangements for redress.

Earlier this year, Ms Hodgson said it was “frankly insulting” that the government had not issued an official response to a 2024 report into the mesh scandal. Government has failed to decide on compensation for the victims.

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Source: HSJ, 3 March 2026

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