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Found 75 results
  1. Content Article
    This study in JAMA Psychiatry aimed to assess whether multivariate machine learning approaches can identify the neural signature of major depressive disorder in individual patients. The study was conducted as a case-control neuroimaging study that included 1801 patients with depression and healthy controls. The results showed that the best machine learning algorithm only achieved a diagnostic classification accuracy of 62% across major neuroimaging modalities. The authors concluded that although multivariate neuroimaging markers increase predictive power compared with univariate analyses, no depression biomarker could be uncovered that is able to identify individual patients.
  2. News Article
    Women who experience depression during pregnancy or in the year after giving birth are at a higher risk of suicide and attempting suicide, researchers have warned. The British Medical Journal study warned that women who develop perinatal depression are twice as likely to die compared to those who don’t experience depression. Suicide was the leading cause of death for women in the UK in 2022 between six weeks and one year after birth, while deaths from psychiatric causes accounted for almost 40 per cent of maternal deaths overall, according to a Perinatal Mortality Surveillance report. Last year an analysis by Labour revealed 30,000 women who were pregnant were on waiting lists for specialist mental health support. The number of women waiting rose by 40 per cent between August 2022 and March 2023. The most recent NHS data shows in September 2023, 61,000 women accessed perinatal mental health services. For 2023-24, the health service must hit a target to have 66,000 women accessing care. In August 2023, the Royal College of Midwives published a research warning half of anxiety and depression cases among new and expectant mothers were being missed amid NHS staff shortages in maternity care. Read full story Source: The Independent, 11 January 2024
  3. Content Article
    This study published in the BMJ found that women with clinically diagnosed perinatal depression were associated with an increased risk of death, particularly during the first year after diagnosis and because of suicide. Women who are affected, their families, and health professionals should be aware of these severe health hazards after perinatal depression.
  4. News Article
    Open letter to government from experts and politicians says rising usage ‘is a clear example of over-medicalisation’. Medical experts and politicians have called for the amount of antidepressants being prescribed to people across the UK to be reduced in an open letter to the government. The letter coincides with the launch of the all-party parliamentary group Beyond Pills, which aims to reduce what it calls the UK healthcare system’s over-reliance on prescription medication. Read full story Source: Guardian, 5 December 2023
  5. News Article
    ChatGPT , the artificial intelligence tool, may be better than a doctor at following recognised treatment standards for depression, and without the gender or social class biases sometimes seen in the physician-patient relationship, a study suggests. The findings were published in Family Medicine and Community Health. The researchers said further work was needed to examine the risks and ethical issues arising from AI’s use. Globally, an estimated 5% of adults have depression, according to the World Health Organization. Many turn first to their GP for help. Recommended treatment should largely be guided by evidence-based clinical guidelines in line with the severity of the depression. ChatGPT has the potential to offer fast, objective, data-based insights that can supplement traditional diagnostic methods as well as providing confidentiality and anonymity, according to researchers from Israel and the UK. Read full story Source: The Guardian, 16 October 2023
  6. Content Article
    Doctors are dying by suicide at higher rates than the general population—somewhere between 300 to 400 physicians a year in the US take their own lives. This article in The Guardian looks at why so many surgeons are dying to suicide and what can be done to stop the trend. It examines how the culture of working long hours and the expectation to be 'superhuman' leads surgeons to suppress their symptoms and avoid seeking help for mental health issues. The article also tells the story of US surgeon and President of the Association of Academic Surgery Carrie Cunningham, who has lived with depression, anxiety and a substance abuse disorder for many years.
  7. Content Article
    This opinion piece is by Luke* who suffers from post-SSRI sexual dysfunction (PSSD) after he was prescribed a selective serotonin reuptake inhibitor (SSRI) antidepressant.  Luke introduces the condition, drawing on the experiences that others have shared through PSSD communities, to highlight the devastating impact on patients. He calls for widespread recognition, improved risk communication and better support for sufferers.  *Name has been changed
  8. Content Article
    In this podcast episode, Rosie, Sean, Carlton, and Emily share their experiences with Post-SSRI Sexual Dysfunction (PSSD), a condition where individuals face persistent sexual side effects and other side effects after taking or discontinuing certain antidepressants. Throughout the conversation, they emphasise the need for increased awareness and research on PSSD, sharing personal stories to shed light on this often-overlooked condition. Despite the challenges they face, they remain determined to advocate for recognition and support for those suffering from PSSD.
  9. Content Article
    In this article, inews columnist Kate Lister looks at the andropause, sometimes called the 'male menopause' that can affect men in their later 40s and early 50s. A gradual decline in testosterone levels can contribute to some men developing depression, loss of sex drive, erectile dysfunction and other physical and emotional symptoms. She looks at current research and views around the issue, highlighting her own bias in initially dismissing the idea and linking this to the societal notion that 'only women are hormonal'. She highlights that although the drop in testosterone men experience is not like the sudden hormonal changes that causes the menopause, men can still experience severe symptoms that require treatment with hormone therapy. "Despite my scoffing at the idea, it turns out that the andropause is very much a real thing that can impact some men very badly. The treatment is exactly the same as it is for women struggling with menopause and perimenopause. It’s hormone replacement therapy: this time in the form of testosterone."
  10. Content Article
    Sexual dysfunction is a common side effect of Serotonergic antidepressants (SA) treatment, and persists in some patients despite drug discontinuation, a condition termed post-SSRI sexual dysfunction (PSSD). The risk for PSSD is unknown but is thought to be rare and difficult to assess. This study, published in the Annals of general psychiatry, aims to estimate the risk of erectile dysfunction (ED) and PSSD in males treated with SAs.
  11. Content Article
    A set of enduring conditions have been reported in the literature involving persistent sexual dysfunction after discontinuation of serotonin reuptake inhibiting antidepressants, 5 alpha-reductase inhibitors and isotretinoin. The objective of this study, published by the International Journal of Safety and Risk in Medicine, was to develop diagnostic criteria for post-SSRI sexual dysfunction (PSSD), persistent genital arousal disorder (PGAD) following serotonin reuptake inhibitors, post-finasteride syndrome (PFS) and post-retinoid sexual dysfunction (PRSD).
  12. Content Article
    During pregnancy, and up to one year after birth, one in five women will experience mental health issues, ranging from anxiety and depression to more severe illness. For those women experiencing mental ill-health, barriers often exist preventing them from accessing care, including variation in availability of service, care, and treatment. These are often worsened by cultural stigma, previous trauma, deprivation, and discrimination. This document by the Royal College of Midwives outlines recommendations to ensure that women are offered, and can access, the right support at the right time during their perinatal journey.
  13. Content Article
    This briefing was commissioned by the Maternal Mental Health Alliance who are dedicated to ensuring all women, babies and their families across the UK have access to compassionate care and high-quality support for their mental health during pregnancy and after birth. One woman in five experiences a mental health problem during pregnancy or after they have given birth. Maternal mental health problems can have a devastating impact on the women affected and their families. NICE guidance states that perinatal mental health problems always require a speedy and effective response, including rapid access to psychological therapies when they are needed. Integrated care systems (ICSs) have a unique opportunity to ensure that all women who need support for their mental health during the perinatal period get the right level of help at the right time, close to home.
  14. News Article
    More than 400,000 children and young people a month are being treated for mental health problems – the highest number on record – prompting warnings of an unprecedented crisis in the wellbeing of under-18s. Experts say Covid-19 has seriously exacerbated problems such as anxiety, depression and self-harm among school-age children and that the “relentless and unsustainable” ongoing rise in their need for help could overwhelm already stretched NHS services. The latest NHS figures show “open referrals” – troubled children and young people in England undergoing treatment or waiting to start care – reached 420,314 in February, the highest number since records began in 2016. The total has risen by 147,853 since February 2020, a 54% increase, and by 80,096 over the last year alone, a jump of 24%. January’s tally of 411,132 cases was the first time the figure had topped 400,000. Mental health charities welcomed the fact that an all-time high number of young people are receiving psychological support. But they fear the figures are the tip of the iceberg of the true number of people who need care, and that many more under-18s in distress are being denied help by arbitrary eligibility criteria. Read full story Source: The Guardian, 22 May 2022
  15. News Article
    People who suffer from severe Covid-19 symptoms are more likely to have long-term mental health problems, a new study suggests. Higher rates of depression and anxiety have been found in people who were “bedridden” with Covid-19 for more than seven days last year, according to a study published in the Lancet. Scientists, drawing on data from 247,249 people across the UK, Denmark, Estonia, Iceland, Norway and Sweden, found that people with coronavirus who were not admitted to hospital were more likely to experience symptoms of depression up to 16 months after diagnosis, compared to those never infected. However, over 16 months, patients who were bedridden for seven days or more were between 50 and 60% more likely to experience higher levels of depression and anxiety compared to people never infected during the study period, the researchers found. Overall, people diagnosed with Covid-19 had a higher prevalence of depression and poorer sleep quality compared with individuals who were never diagnosed – 20% of those in the former group experienced symptoms of depression, versus 11% in the latter group. Researchers suggested patients who spent longer in bed or had higher depression or anxiety rates could be suffering from ill health due to a combination of worrying about long-term health effects and Covid symptoms persisting. Patients with severe Covid often experience inflammation, which has previously been linked to chronic mental illness, particularly depression. Read full story Source: The Independent, 15 March 2022
  16. News Article
    Thousands of women in England with mental health problems are being given electric shock treatment despite concerns the therapy can cause irreparable brain damage. NHS data seen by The Independent reveals the scale of electroconvulsive therapy (ECT) prescribed disproportionately to women, who make up two-thirds of patients receiving the treatment. Health professionals have warned the therapy can cause brain damage so severe recipients are unable to recognise family and friends or do basic maths. While some patients say the therapy profoundly helped them, leading mental charities have branded it “damaging” and “outdated” and called for its use to be halted pending an urgent review or banned entirely. Statistics obtained through Freedom of Information requests by Dr John Read, a professor at the University of East London and leading expert on ECT, showed 67% of 1,964 patients who received the treatment in 2019 were female. ECT was given to women twice as often as men across 20 NHS trusts in the UK, his research found. The trusts also said some 36% of their patients in 2019 underwent ECT without providing consent. A spokesperson added patients should be fully informed of the risks associated with ECT and the decision to deploy the treatment “should be made jointly with the person with depression as far as possible”. Read full story Source: The Independent, 19 June 2022
  17. News Article
    Children suffering mental health crises spent more than 900,000 hours in A&E in England last year seeking urgent and potentially life-saving help, NHS figures reveal. Experts said the huge amount of time under-18s with mental health issues were spending in A&E was “simply astounding” and showed that NHS services for that vulnerable age group were inadequate. Children as young as three and four years old are among those ending up in emergency departments because of mental health problems, according to data obtained by Labour. Dr Rosena Allin-Khan, the shadow mental health minister, who is also an A&E doctor, said: “With nowhere to turn, children with a mental illness are left to deteriorate and reach crisis point – at which time A&E is the only place left for them to go. Emergency departments are incredibly unsuitable settings for children in crisis, yet we’re witnessing increasingly younger children having to present to A&E in desperation.” Young people who endured long A&E waits included those with depression, psychosis and eating disorders as well as some who had self-harmed or tried to kill themselves, doctors said. Read full story Source: The Guardian, 9 February 2023
  18. News Article
    A man has waited eight years to get adequate mental health care, as waiting lists for therapy grow. Myles Cook, 47, from Essex, lives with severe depression and has been fighting to get one-to-one counselling for eight years but he has been told there are not enough therapists locally to respond to the demand. Instead, he has been referred to group sessions, which he said were “detrimental” to his condition and manages his condition with medication but said he did not find that helpful either. He said: “If you’re not getting help, and all you keep getting are pills and pills that don’t seem to be doing much. It might take the edge off but it doesn’t really do anything for my depression and because of the way the benefits system works, I’m not getting any therapy If I’m not on tablets, they’ll probably kick me off on my benefits because I’m not being treated.” “I take the tablets, the psychiatric medications, I keep taking them although they’re not helpful because I need to have something to prove that I’m being treated to keep my benefits.” At least 95% of patients needing NHS talking therapy services, called IAPT, should receive treatment within 18 weeks. But figures previously uncovered by The Independent showed that just one in five patients have their second IAPT appointment within three months. And the NHS has failed to meet its target of having 1.6 million patients seen by IAPT services last year. Data published last year shows this was missed by 400,0000 at the end of 2021-22. Read full story Source: The Independent, 16 January 2023
  19. News Article
    GPs whose patients want to stop taking antidepressants should reduce the dose of their medication in stages to lower the risk and severity of withdrawal symptoms, the medicines watchdog has said. About one in six (16%) adult Britons experience moderate to severe depression, according to the Office for National Statistics. In England alone, 21.4m antidepressant drugs were prescribed between July and September 2022, according to the NHS Business Services Authority. A new draft quality standard for the care of adults with depression from the National Institute for Health and Care Excellence (NICE) – the first update in 11 years – includes specific guidance to help adults come off antidepressant medication permanently. NICE’s independent advisory committee, which includes experts in treating adults with depression, recommends the staged withdrawal of antidepressants in patients who want to stop taking the drugs. A staggered reduction of medicine, known as tapering, helps to reduce withdrawal effects and long-term dependence on the medication, according to Nice. The committee said primary care and mental health professionals should follow the NICE guideline recommendations on stopping antidepressant medication, including agreeing with their patient whether it is right for them to stop taking the medication and, if so, the speed and duration of withdrawal from it. Read full story Source: The Guardian, 17 January 2023
  20. News Article
    An NHS trust declined to provide care for a vulnerable Black man days before he died in police custody while having a psychotic episode, The Independent has learnt. Godrick Osei, 35, died after being restrained by up to seven Devon and Cornwall Police officers in the early hours of 3 July 2022, after fleeing his flat and hiding in the cupboard of a care home in Truro. His family said he had been expressing “paranoid thoughts” and had called the police himself for help. He was arrested and died within an hour. Mr Osei had been diagnosed with anxiety and depression, had suspected post-traumatic stress disorder (PTSD) and was prescribed various medications to treat these conditions. He also intermittently used illicit drugs and had suffered alleged sexual assault in prison around 2013, according to a medical report from North East London NHS Foundation Trust (NELFT). In the days before his death, Mr Osei was in the care of NELFT’s community mental health team, whose caseworkers were concerned that he was exhibiting signs of a further severe illness – emotionally unstable personality disorder (EUPD) – and was a high risk to himself. However, Mr Osei was based outside the team’s catchment area, and NELFT asked the neighbouring Cornwall Partnership NHS Foundation Trust (CPT) to assess him instead. CPT refused without explaining why, according to a medical report seen by The Independent. Following Mr Osei’s death, an investigating officer from NELFT made multiple attempts to contact CPT to explore the possibility of a joint investigation into the matter, but didn’t receive a response. Read full story Source: The Independent, 16 January 2023
  21. News Article
    The number of children in England needing treatment for serious mental health problems has risen by 39% in a year, official data shows. Experts say the pandemic, social inequality, austerity and online harm are all fuelling a crisis in which NHS mental health treatment referrals for under-18s have increased to more than 1.1m in 2021-22. In 2020-21 – the first year of the pandemic – the figure was 839,570, while in 2019-20 there were 850,741 referrals, according to analysis of official figures by the PA Media. The figures include children who are suicidal, self-harming, suffering serious depression or anxiety, and those with eating disorders. Dr Elaine Lockhart, chair of the child and adolescent psychiatry faculty at the Royal College of Psychiatrists, said the rise in referrals reflected a “whole range” of illnesses. She said “specialist services are needing to respond to the most urgent and the most unwell”, including young people suffering from psychosis, suicidal thoughts and severe anxiety disorder. Lockhart said targets for seeing children urgently with eating disorders were sliding “completely” and that more staff were needed. Read full story Source: The Guardian, 3 January 2023
  22. News Article
    Antidepressants can cause severe, sometimes irreversible, sexual dysfunction that persists even after discontinuing the medication. Sufferers have described it as ‘chemical castration’ – a type of genital mutilation caused by antidepressants, mainly selective serotonin reuptake inhibitors (SSRIs). The condition is known as post-SSRI sexual dysfunction (PSSD), a condition largely unrecognised, and the true incidence of which is unknown. David Healy, psychiatrist and founder of RxISK.org said, “I saw my first patient with PSSD in 2000, a 35-year-old lady who told me that three months after stopping treatment, she could rub a hard-bristled brush across her genitals and feel nothing.” David Healy, psychiatrist and founder of RxISK.org said, “I saw my first patient with PSSD in 2000, a 35-year-old lady who told me that three months after stopping treatment, she could rub a hard-bristled brush across her genitals and feel nothing.” Josef Witt-Doerring, psychiatrist and former FDA medical officer said, “This condition is so devastating that it will cause serious changes to your life and to those around you.” Read full story Source: Maryanne Demasi, 13 June 2023
  23. News Article
    Many media stories about ketamine as a treatment for psychiatric disorders such as depression “go well beyond the evidence base” by exaggerating the efficacy, safety and longevity of the drug or by overstating the risks, an analysis has found. Researchers examined 119 articles about ketamine and mental illness published by major print media in Australia, the US and UK over a five-year period. They found articles peaked in 2019, when the US Food and Drug Administration approved a ketamine-derived nasal spray known as esketamine for treatment-resistant depression. Researchers found 37% of articles contained inaccurate information, largely related to efficacy, safety information and the longevity of the effect of the treatment. Ketamine treatment was portrayed in an “extremely positive light” in 69% of articles, the review found. “Overly optimistic statements from medical professionals regarding efficacy or safety may encourage patients to seek treatments that may not be clinically appropriate,” says the paper, published in the journal BJPsych Open. “Disconcertingly, some articles included strong statements about treatment efficacy that went well beyond the evidence base. Conversely, exaggeration of the risks may discourage patients from pursuing a treatment that may be suitable for them.” Read full story Source: The Guardian, 8 June 2023
  24. News Article
    A therapy using magnets to treat severe depression is available on the NHS in the West for the first time. Wellsprings clinic in Taunton can now deliver the repetitive Transcranial Magnetic Stimulation treatment (rTMS) to NHS patients through a referral. During a session, a strong magnetic field is used to stimulate or inhibit different parts of the brain. The National Institute for Health and Care Excellence (NICE) said it had "no major safety concerns" for the therapy. Mark Rickman, 60, from Dartmoor deals with bipolar and depression and said rTMS has had a positive impact on him. Mr Rickman previously tried Electroconvulsive Therapy (ECT), where electric shocks cause a brief surge of electrical activity in the brain, but said it was "debilitating" compared to rTMS. NICE cleared rTMS for use in 2015, for people who had not responded well to antidepressants, and had "no major concerns" about the therapy. The main side effects were said to be headaches, and patients at risk of seizures are screened. Read full story Source: BBC News, 18 May 2023
  25. News Article
    Nine online talking-therapy treatments for anxiety or depression have been given the green light to be used by the NHS in England. They offer faster access to help but less time with a therapist, which may not suit everyone, the health body recommending them said. There is huge demand for face-to-face services, with people waiting several weeks to see a therapist. The new digital therapies, delivered via a website or an app using cognitive-behavioural therapy (CBT), provide an alternative way of accessing support, which may be more convenient for some, the National Institute for Health and Care Excellence (NICE) says. They could also free up resources and help reduce the wait for care. However, psychiatrists said digital therapies were not a long-term solution. Mental-health charity Sane said they were no substitute for a one-to-one relationship and could leave people feeling even more isolated than before. Read full story Source: BBC News, 16 May 2023
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