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News Article
Young people more likely to suffer rare vaccine blood clots, MHRA says
Patient Safety Learning posted a news article in News
Younger adults are particularly affected by the rare blood clotting disorder linked to the Oxford-AstraZeneca vaccine, the UK's medicines regulator has said. The Medicines and Healthcare products Regulatory Agency (MHRA) said there were 209 cases in the UK of the rare combination of blood clots with low platelet counts following being vaccinated the Oxford-AstraZeneca jab, with 41 deaths, up to 21 April. This is up from 168 cases and 32 deaths the previous week. The new data also shows 24 cases of clots in people aged 18 to 29, 28 in those in their thirties, 30 in people in their forties, 59 in people in their fifties and 57 in those aged 60 and above, with the age not known in the remaining cases. The numbers appear to rise with age but that is because more older people have been vaccinated. Fewer than one in five clots was fatal. The latest NHS England data show that 5.5 million people under 45 had received a first dose by 25 April, while 22.6 million of those 45 and over had done so. MHRA chief executive June Raine said no medicine or vaccine was without risk, but that blood clots were extremely rare. She added: “The benefits of the vaccine continue to outweigh the risks for most people. It is still vitally important that people come forward for their vaccination when invited to do so." Read full story Source: The Independent, 3 May 2021 -
News Article
Consultant who carried out unauthorised research loses challenge over dismissal
Patient Safety Learning posted a news article in News
A consultant at St Luke’s Hospital in Kilkenny who carried out unauthorised research on five female patients during routine gynaecological procedures has failed in a High Court challenge to prevent his dismissal by the HSE. Consultant gynaecologist Ray O’Sullivan claimed a decision by the HSE’s chief executive, Paul Reid, on December 23rd, 2019 to recommend his dismissal was “fatally flawed” for reasons including a failure to allow him the opportunity to comment on an expert’s report into his professional performance. The hospital began an investigation after nursing staff expressed concern about the risk of infection from a procedure carried out on five patients on September 4th and 5th, 2018 under the direction of Prof O’Sullivan. A catheter and small pressure pad was placed, without their consent and without seeking approval from the hospital’s ethics committee, inside the vagina of five patients who were having a hysteroscopy. This was done as part of a feasibility study designed to see if certain procedures could be carried out without the use of a speculum (a device commonly used in vaginal exams) . The court heard the five patients, who were tested for infection including HIV, were greatly shocked and upset when St Luke’s informed them about what happened at open disclosure meetings. Read full story Source: The Irish Times, 27 April 2021 -
News ArticleGood quality evidence is urgently needed to inform doctors on how to discontinue antidepressants safely and effectively, a Cochrane review has highlighted. An international team of researchers assessed randomised controlled trials comparing approaches to discontinuation and continuation of antidepressants in patients who had used them for depression or anxiety for at least six months. But the team reached no firm conclusions about the effects and safety of the approaches reviewed because of the low certainty of evidence from the existing studies. Read full story (paywalled) Source: BMJ, 22 April 2021
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News ArticlePregnant women who catch COVID-19 are over 50% more likely to experience severe complications such as premature birth, admission to intensive care and death, a major study has found. Newborns of infected women were also nearly three times more at risk of severe medical complications and close to 10% tested positive during the first few days of their life, the study of more than 2,100 pregnant women across 18 countries worldwide revealed. Scientists leading the study warned the risk to mothers and babies is greater than acknowledged at the beginning of the pandemic, and called for pregnant women to be offered a COVID-19 vaccine. Stephen Kennedy, a professor of reproductive medicine at the University of Oxford, who co-led the study, said: “We now know that the risks to mothers and babies are greater than we assumed at the start of the pandemic and that known health measures when implemented must include pregnant women. “The information should help families, as the need to do all one can to avoid becoming infected is now clear. Read full story Source: The Independent, 24 April 2021
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News Article
Influenza drug ‘good contender’ for at-home treatment against COVID-19
Patient Safety Learning posted a news article in News
An antiviral typically used to treat influenza is a “good contender” for a drug that could be taken at home by people infected with COVID-19, according to a scientist who is trialling the medicine. Favipiravir, licensed as a flu treatment in Japan since 2014, has already shown potential in reducing lung damage in hospitalised Covid patients and speeding up the time taken to clear the virus from the body. But two UK trials, in Glasgow and London, are investigating whether the drug could be taken by people in the community before their disease has progressed, therefore keeping them out of hospital. The government has promised to “supercharge” the search for and development of a new generation of easy-to-take, at-home drugs that can reduce transmission and quicken recovery from COVID-19. A new taskforce, modelled on the team behind Britain’s vaccine procurement programme, is to oversee this work. It intends to deliver two effective treatments - offered in tablet form - to the public as early as autumn. Read full story Source: The Independent, 22 April 2021 -
News ArticleOne in three people who were severely ill with coronavirus were subsequently diagnosed with a neurological or psychiatric condition within six months of infection, a study has found. The observational research, which is the largest of its kind, used electronic health records of 236,379 patients mostly from the US and found 34% experienced mental health and neurological conditions afterwards. The most common being anxiety, with 17% of people developing this. Experts warned that healthcare systems need to be resourced to deal with patients affected by this, which could be “substantial” given the scale of the pandemic. They anticipate that the impact could be felt on health services for many years. Neurological diagnoses such as stroke and dementia were rarer, but not uncommon in those who had been seriously ill during infection. Of those who had been admitted to intensive care, 7% had a stroke and almost 2% were diagnosed with dementia. The study, which was published in the Lancet Psychiatry, found that these diagnoses were more common in COVID-19 patients than among those who had the flu or respiratory tract infections over the same time period. Read full story Source: The Guardian, 7 April 2021
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News ArticleThat throbbing headache just won’t go away and your mind is racing about what may be wrong. But Googling your symptoms may not be as ill-advised as previously thought. Although some doctors often advise against turning to the internet before making the trudge up to the clinic, a new study suggests that using online resources to research symptoms may not be harmful after all – and could even lead to modest improvements in diagnosis. Using “Dr Google” for health purposes is controversial. Some have expressed concerns that it can lead to inaccurate diagnoses, bad advice on where to seek treatment (triage), and increased anxiety (cyberchondria). Previous research into the subject has been limited to observational studies of internet search behaviour, so researchers from Harvard sought to empirically measure the association of an internet search with diagnosis, triage, and anxiety by presenting 5,000 people in the United States with a series of symptoms and asked them to imagine that someone close to them was experiencing the symptoms. The participants – mostly white, average age 45, and an even gender split – were asked to provide a diagnosis based on the given information. Then they looked up their case symptoms (which, ranging from mild to severe, described common illnesses such as viruses, heart attacks and strokes) on the internet and again offered a diagnosis. As well as diagnosing the condition, participants were asked to select a triage level, ranging from “let the health issue get better on its own” to calling the emergency services. Participants also recorded their anxiety levels. The results showed a slight uptick in diagnosis accuracy, with an improvement of 49.8% to 54% before and after the search. However, there was no difference in triage accuracy or anxiety, the authors wrote in the journal JAMA Network Open. These findings suggest that medical experts and policymakers probably do not need to warn patients away from the internet when it comes to seeking health information and self-diagnosis or triage. It seems that using the internet may well help patients figure out what is wrong. Read full story Source: The Guardian, 29 March 2021
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News Article
Miscarriage associated with higher risk of women’s early death
Patient Safety Learning posted a news article in News
Miscarriage may be associated with an increased risk of early death, researchers have said. The BMJ published a study suggesting that this risk is particularly acute for those who have experienced repeated miscarriages, especially ones that occurred early on in a woman’s life. US-based researchers said that women who had experienced a miscarriage were 19% more likely to die prematurely. They pointed out that a miscarriage “could be an early marker of future health risk in women.” The authors of the paper hoped to see if there was any link between miscarriage and a risk of death before the age of 70. Data used was taken from 101,681 women as part of the Nurses’ Health Study in the US. This was made up of female nurses aged between 25 and 42 years. The researchers followed the women for 24 years and said that 2,936 premature deaths were recorded, this included 1,346 from cancer and 269 from cardiovascular disease. It appeared that death rates from all causes were comparable both for women with and without a history of miscarriage. However, rates were higher for women who had experienced three or more miscarriages as well as for women who had their first miscarriage under the age of 24. The study found that the association between miscarriage, or “spontaneous abortion,” and premature death was strongest for deaths from cardiovascular disease. Read full story Source: The Independent, 25 March 2021 -
News Article
Middle-aged women 'worst affected by long Covid', studies find
Patient Safety Learning posted a news article in News
Middle-aged women experience the most severe, long-lasting symptoms after being treated in hospital for COVID-19, two UK studies suggest. Five months on, 70% of patients studied were still affected by everything from anxiety to breathlessness, fatigue, muscle pain and "brain fog". But the researchers say there is no obvious link with how ill people originally became. How women's bodies fight off illness could explain their poorer recovery. The larger study - led by the University of Leicester - which is yet to be peer-reviewed, followed up more than 1,000 patients who had been admitted to hospital with Covid-19 in the UK last year. It found that up to 70% had not fully recovered, an average of five months after leaving hospital, with women most affected. A separate smaller pre-print study, led by University of Glasgow, found women under 50 were seven times more likely to be more breathless, and twice as likely to report worse fatigue than men of the same age who had had the illness, seven months after hospital treatment. Read full story Source: BBC News, 25 March 2021 -
News Article
Covid: Nurses condemn 'fundamentally flawed' PPE rules
Patient Safety Learning posted a news article in News
Nurse leaders are lobbying government to update "fundamentally flawed" guidance on personal protective equipment. The Royal College of Nursing says the existing recommendations are based on out-of-date evidence. One nurse told the BBC she had not been allowed to wear a higher-grade mask, despite having to go into the homes of patients with Covid. The nurse, who wishes to remain anonymous, wanted to use what's known as an FFP3 mask that filters out infectious aerosols. But she says her employers insisted on following national guidance, that most health staff should wear thinner surgical masks, instead. This comes at a time of mounting concern among many healthcare organisations that personal protective equipment (PPE) is inadequate. A new report for the Royal College of Nursing (RCN) criticises the official guidelines for PPE as "fundamentally flawed" because they're based on out-of-date evidence. It says that the risk of infection by aerosols is not given enough emphasis and that key research papers highlighting the possibility of airborne transmission have not been considered. The RCN's report concludes that key research papers on aerosols appear to have been ignored and that the terms used to search for new papers were likely to be "biased against" those on airborne transmission. The lead author of the study, Prof Dinah Gould, says she is "very disappointed" at the review for not taking into account the latest science. "A year into the pandemic, the review needs replacing. It needs updating and we should be able to offer healthcare workers and patients better than what we're offering them now." Read full story Source: BBC News, 7 March 2021 -
News Article
Data on Long Covid in UK children is cause for concern, scientists say
Patient Safety Learning posted a news article in News
Scientists have warned that emerging data on Long Covid in children should not be ignored given the lack of a vaccine for this age group, but cautioned that the evidence describing these enduring symptoms in the young is so far uncertain. Recently published data from the Office for National Statistics (ONS) suggests that 13% of under 11s and about 15% of 12 to 16 year olds reported at least one symptom five weeks after a confirmed COVID-19 infection. Although children are relatively less likely to become infected, transmit the virus and be hospitalised, the key question is whether even mild or asymptomatic infection can lead to Long Covid in children, said Danny Altmann, professor of immunology at Imperial College London. “The answer is that it certainly can, and the Long Covid support groups contain a not insignificant number of children and teens,” Altmann said. Frances Simpson, a lecturer in psychology at Coventry University and co-founder of the Long Covid Kids group, said she was very worried about the emerging data on Long Covid in children. “We just think that there should be a much more cautious and curious approach to long Covid rather than a kind of a sweeping generalisation that children are OK, and that we should just let them all go back to school without any measures being put in place.” One issue, she said, is the sizeable gap between acute infection and Long Covid kicking off. Some children are initially asymptomatic or have mild symptoms but then it might be six or seven weeks before they start experiencing long Covid symptoms, which can range from standard post-viral fatigue and headaches to neuropsychiatric symptoms such as seizures, or even skin lesions." At the moment there is no consensus on the scale and impact of long Covid in adults, but emerging data is concerning. For children, the data is even more scarce. Recent reports from hospitals in Sweden and Italy have generated concern, but this data is not from national trials – they are single-centre studies – and include relatively small patient numbers, said Sir Terence Stephenson, a Nuffield professor of child health at University College London. Stephenson was awarded £1.36m last month to lead a study investigating Long Covid in 11- to 17-year-olds. “I don’t have a scientific view on what long Covid is in young people is – because frankly, we don’t know,” he said. Preliminary results are expected in three months. Read full story Source: The Guardian, 2 March 2021 -
News ArticleA new COVID vaccine efficacy study from Israel has concluded that Pfizer/BioNTech's jab is up to 85% effective after the first dose. The research, conducted by the Sheba Medical Centre, the country's largest hospital, has been published in the Lancet medical journal. The hospital assessed the effectiveness of the first dose of the Pfizer/BioNTech vaccine among 7,000 of its healthcare employees. The workers each received their first dose in January and the research team observed an 85% reduction of clinical (symptomatic) COVID-19 between 15 and 28 days after the jab. But critically, they also observed efficacy in asymptomatic patients. The study found that all infections, including asymptomatic, were reduced by 75% after the first dose. Professor Eyal Leshem, an infectious disease expert and director of Sheba's Institute for Travel and Tropical Medicine, told Sky News: "This is first real-world evidence of effectiveness that shows up after the first dose of the vaccine." Read full story Source: Sky News, 19 February 2021
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News ArticleAt home early abortions pose no greater risk and allow women to have the procedure much earlier on in their pregnancy, research has found. The findings have sparked calls from leading healthcare providers for the option, which was rolled out in the wake of lockdown measures last spring, to be made permanent. Researchers, who conducted the UK’s largest study into abortions, discovered there were no cases of significant infection which necessitated the woman to go to hospital or have major surgery. The study, conducted by the British Pregnancy Advisory Service and MSI Reproductive Choices, drew attention to the fact that despite misinformation to the contrary, not one individual died from having an at home early abortion. Eight in ten women said at home abortions were their preferred choice and they would opt for it in the future, while waiting times from when the woman has her consultation to treatment improved from 11 days to 7 days. Dr Jonathan Lord, medical director for MSI Reproductive Choices UK, said: “Being able to access abortion care earlier in pregnancy has also reduced the low complication rate even further.” Dr Lord added: “Telemedicine has provided a lifeline for vulnerable women and girls who cannot attend consultations in-person. We have seen a major increase in safeguarding disclosures, including from survivors of domestic and sexual violence, as they can talk more freely about distressing and intimate details from the privacy of their own home at the beginning of the Covid emergency." Read full story Source: The Independent, 19 February 2021
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News ArticleA trial of an experimental coronavirus vaccine detected the most sobering signal yet that people who have recovered from infections are not completely protected against a variant that originated in South Africa and is spreading rapidly, preliminary data presented this week suggests. The finding, though far from conclusive, has potential implications for how the pandemic will be brought under control, underscoring the critical role of vaccination, including for people who have already recovered from infections. Reaching herd immunity — the threshold when enough people achieve protection and the virus can’t seed new outbreaks — will depend on a mass vaccination campaign that has been constrained by limited supply. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, noted that it appears a vaccine is better than natural infection in protecting people, calling it “a big, strong plug to get vaccinated” and a reality check for people who may have assumed that because they have already been infected, they are immune. Read full story Source: The Washington Post, 6 February 2021
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News ArticleThousands of women living in the UK suffering from an aggressive type of breast cancer could be helped by a newly identified drug, according to a study. The research, carried out by The Institute of Cancer Research, found medicine presently used to help other breast cancers that have spread to another area of the body, could actually be utilised to help around a fifth of women who have triple negative breast cancer. Around 55,000 women are diagnosed with breast cancer in Britain each year, with approximately one in five of these being triple negative. Younger women and black women are more likely to develop this form of breast cancer which is generally more aggressive. Researchers’ realisation the drug palbociclib could be used far more widely than previously thought could “provide a much-needed targeted treatment” for those who are at higher risk of witnessing their cancer spread more quickly, becoming incurable and often unresponsive to conventional chemotherapy. Dr Simon Vincent, of Breast Cancer Now, a leading charity which funded the study, said: “It’s hugely exciting that this research has uncovered a new possible use for palbociclib as a targeted treatment for some women living with triple negative breast cancer." Read full story Source: The Independent, 28 January 2021
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News ArticleNew research has suggested there are specific molecular responses found in some COVID-19 patients which could be used to determine their likelihood of suffering from severe or long Covid symptoms, very early on following infection. Researchers, supported by NIHR Cambridge Biomedical Research Centre, had set out to increase our understanding of the relationship between the immune response and COVID-19 symptoms by recruiting individuals who tested positive for the virus into a cohort of the NIHR BioResource. Studying 207 people who had tested positive for COVID-19 over a three-month period, taking blood samples and measuring their symptoms, then comparing to samples taken from 45 healthy people, the researchers were able to uncover a number of interesting new findings. Their research showed that people with either an asymptomatic or mild case of COVID-19 mounted a robust immune response to the virus soon after getting infected. These individuals produced a greater number of T cells, B cells and antibodies than patients with more severe COVID-19 infections and within the first week of infection - after which these numbers rapidly returned to normal. The study also showed there was no evidence in these patients of widespread inflammation which can lead to damage in multiple organs. In contrast, people with severe COVID-19 who required hospitalisation showed an impaired immune response, which led to a delayed and weakened attempt to fight the virus and widespread inflammation from the time of symptom onset. In patients requiring admission to hospital, the early immune response was delayed, and profound abnormalities were present in a number of immune cells. Read full story Source: NHE, 22 January 2021
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News ArticleA new state of the art institute for antimicrobial research is to open at Oxford University thanks to a £100 million donation from Ineos. Ineos, one of the world’s largest manufacturing companies, and the University of Oxford are launching a new world-leading institute to combat the growing global issue of antimicrobial resistance (AMR), which currently causes an estimated 1.5 million excess deaths each year- and could cause over 10m deaths per year by 2050. Predicted to also create a global economic toll of $100 trillion by mid-century, it is arguably the greatest economic and healthcare challenge facing the world post-Covid. It is bacterial resistance, caused by overuse and misuse of antibiotics, which arguably poses the broadest threat to global populations. The world is fast running out of effective antibiotics as bacteria evolve to develop resistance to our taken-for-granted treatments. Without urgent collaborative action to prevent common microbes becoming multi-drug resistant (commonly known as ‘superbugs’), we could return to a world where taken-for-granted treatments such as chemotherapy and hip replacements could become too risky, childbirth becomes extremely dangerous, and even a basic scratch could kill. The rapid progression of antibacterial resistance is a natural process, exacerbated by significant overuse and misuse of antibiotics not only in human populations but especially in agriculture. Meanwhile, the field of new drug discovery has attracted insufficient scientific interest and funding in recent decades meaning no new antibiotics have been successfully developed since the 1980s. Alongside its drug discovery work, the IOI intends to partner with other global leaders in the field of Antimicrobial Resistance (AMR) to raise awareness and promote responsible use of antimicrobial drugs. The academic team will contribute to research on the type and extent of drug resistant microbes across the world, and critically, will seek to attract and train the brightest minds in science to tackle this ‘silent pandemic’. Read full story Source: University of Oxford, 19 January 2021
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News ArticleCOVID-19 patients in England's busiest intensive care units (ICUs) in 2020 were 20% more likely to die, University College London research has found. The increased risk was equivalent to gaining a decade in age. By the end of 2020, one in three hospital trusts in England was running at higher than 85% capacity. Eleven trusts were completely full on 30 December, and the total number of people in intensive care with Covid has continued to rise since then. The link between full ICUs and higher death rates was already known, but this study is the first to measure its effect during the pandemic. Tighter lockdown restrictions are needed to prevent hospitals from being overwhelmed, says study author Dr Bilal Mateen. Researchers looked at more than 4,000 patients who were admitted to intensive care units in 114 hospital trusts in England between April and June last year. They found the risk of dying was almost a fifth higher in ICUs where more than 85% of beds were occupied, than in those running at between 45% and 85% capacity. That meant a 60-year-old being treated in one of these units had the same risk of dying as a 70-year-old on a quieter ward. The Royal College of Emergency Medicine sets 85% as the maximum safe level of bed occupancy. However, the team found there was no tipping point after which deaths rose - instead, survival rates fell consistently as bed-occupancy increased. This suggests "a lot of harm is occurring before you get to 85%". Read full story Source: BBC News, 14 January 2021
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News Article
Large trial of new covid treatment begins in UK
Patient Safety Learning posted a news article in News
A large-scale trial of a new treatment it is hoped will help stop COVID-19 patients from developing severe illness has begun in the UK. The first patient received the treatment at Hull Royal Infirmary on Tuesday afternoon. It involves inhaling a protein called interferon beta which the body produces when it gets a viral infection. The hope is it will stimulate the immune system, priming cells to be ready to fight off viruses. Early findings suggested the treatment cut the odds of a COVID-19 patient in hospital developing severe disease - such as requiring ventilation - by almost 80%. It was developed at Southampton University Hospital and is being produced by the Southampton-based biotech company, Synairgen. Read full story Source: BBC News, 13 January 2021 -
News Article
Covid: Gut bacteria may influence disease severity, study suggests
Patient Safety Learning posted a news article in News
A coronavirus patient's gut bacteria may influence the length and severity of their infection and their immune response to it, a new study suggests. A team of researchers at The Chinese University of Hong Kong examined whether the variety and quantity of microbiome played a role in COVID-19 infections. Researchers found that patients with COVID-19 were depleted in gut bacteria known to modify a person's immune response, and that this depletion appeared to persist 30 days after the virus had gone. Gut bacteria — or gut microbiome — help to digest food. But research increasingly shows that gut bacteria also affect our health. The study, published in the journal Gut, found that the composition of gut microbiome had changed in COVID-19 patients, compared to those who did not have the infection. It said that gut microbiome could be involved in the "magnitude of COVID-19 severity possibly via modulating host immune responses". Read full story Source: The Independent, 12 January 2021 -
News Article
New edition of The Journal of Patient Safety issued
Clive Flashman posted a news article in News
The latest edition of the Wolters Kluwer Journal of Patient Safety has just been published. Original studies include: Is There a Mismatch Between the Perspectives of Patients and Regulators on Healthcare Quality? A Survey Study The Ideal Hospital Discharge Summary: A Survey of U.S. Physicians Impact of an Original Methodological Tool on the Identification of Corrective and Preventive Actions After Root Cause Analysis of Adverse Events in Health Care Facilities: Results of a Randomized Controlled Trial Detach Yourself: The Positive Effect of Psychological Detachment on Patient Safety in Long-Term Care Patient Safety Activity Under the Social Insurance Medical Fee Schedule in Japan: An Overview of the 2010 Nationwide Survey Sustaining Teamwork Behaviors Through Reinforcement of TeamSTEPPS Principles Prescribing Errors With Low-Molecular-Weight Heparins Development and Psychometric Evaluation of the Speaking Up About Patient Safety Questionnaire Descriptive Analysis of Patient Misidentification From Incident Report System Data in a Large Academic Hospital Federation Medication Errors at Hospital Admission and Discharge: Risk Factors and Impact of Medication Reconciliation Process to Improve Healthcare Reducing and Sustaining Duplicate Medical Record Creation by Usability Testing and System Redesign Full articles are payalled but the abstracts may be viewed free of charge. Access the Journal here -
News Article
£7.5m Covid-19 vaccine study for pregnant women launches in Manchester
Clive Flashman posted a news article in News
The country’s largest clinical study is being launched in Greater Manchester to investigate the best gap between first and second Covid-19 vaccine doses for pregnant women. Led by St George’s, University of London, the Preg-CoV study will provide vital clinical trial data on the immune response to vaccination at different dose intervals – either four to six weeks or eight to 12 weeks. This data will help determine the best dosage interval and reveal more about how the vaccine works to protect pregnant mothers and their babies against Covid-19. Pregnant women are more likely to develop severe Covid-19 or die from the disease but are excluded from clinical trials with new vaccines. This means there are currently very limited clinical trial data on the immune response and side effects caused by the vaccines for these women. Read the full story here Source: National Health Executive -
News Article
New NRLS national patient safety incident reports commentary released
Clive Flashman posted a news article in News
New commentary interprets the data published in the national patient safety incident reports (NaPSIR) for England in September 2021. Access the commentary here (PDF, 20 pages) -
News Article
Call for investigation of menstrual changes after Covid jabs
Patient Safety Learning posted a news article in News
Changes to periods and unexpected vaginal bleeding after having a Covid vaccine should be investigated to reassure women, says a leading immunologist specialising in fertility. Writing in the BMJ, Dr Victoria Male, from Imperial College London, said the body's immune response was the likely cause, not something in the vaccines. There is no evidence they have any impact on pregnancy or fertility. The UK's regulator has received more than 30,000 reports of period problems. These include heavier than usual periods, delayed periods and unexpected bleeding after all three Covid vaccines, out of more than 47 million doses given to women in the UK to date. After reviewing the reports, the Medicines and Healthcare products Regulatory Agency (MHRA) says it "does not support a link" between Covid vaccines and the symptoms. However, writing in an opinion piece in the BMJ, Dr Male says "robust research" into reports of period problems would help to counter misinformation around the vaccines. "Vaccine hesitancy among young women is largely driven by false claims that COVID-19 vaccines could harm their chances of future pregnancy. Failing to thoroughly investigate reports of menstrual changes after vaccination is likely to fuel these fears." "If a link between vaccination and menstrual changes is confirmed, this information will allow people to plan for potentially altered cycles," she said. Read full story Source: BBC News, 16 September 2021 -
News Article
UCLH awarded £6.8 million to conduct long Covid study
Patient-Safety-Learning posted a news article in News
UCLH has been awarded £6.8m to conduct what has been regarded as the largest Long Covid clinical study and will focus on understanding the condition, how to diagnose it, manage it and improve the recovery process. The research will be a collaborative effort and will include 30 researchers, health professionals, patients and industry partners from more than 30 organisations and the project will be known as TIMULATE-ICP (Symptoms, Trajectory, Inequalities and Management: Understanding Long-Covid to Address and Transform Existing Integrated Care Pathways). Read full story. Source: National Health Executive, 19 July 2021
