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Found 10 results
  1. Content Article
    There are limited prospective long-term real-world safety data after faecal microbiota transplantation (FMT). This study reported long-term outcomes of FMT from a population-based FMT registry in Hong Kong. The results demonstrate that FMT has an excellent long-term safety profile and the risk of developing new medical conditions beyond 12 months after FMT is low.
  2. Content Article
    Many people with Long Covid experience varying levels of long-term cognitive impairment, but the causes of this are not well understood. This preprint longitudinal observational study aimed to identify links between cognitive impairment and different biomarkers in people with Long Covid. The authors reported the findings of 128 prospectively studied patients who had tested positive for Covid. They looked at: lung function, physical and mental health at two months post diagnosis. blood cytokines, neuro-biomarkers and kynurenine pathway (KP) metabolites at 2-, 4-, 8- and 12-months post diagnosis. The study identified that KP metabolites were significantly associated with cognitive decline and could therefore offer a potential therapeutic target for treating cognitive impairment related to Long Covid.
  3. Content Article
    This study in the British Journal of General Practice aimed to examine the impact of Covid-19 on GP contacts with children and young people in England. The authors conducted a longitudinal trends analysis using electronic health records from the Clinical Practice Research Datalink (CPRD) Aurum database. The study found that: GP contacts fell 41% during the first lockdown compared with previous years. Children aged 1-14 years had greater falls in total contacts (≥50%) compared with infants and those aged 15–24 years. Face-to-face contacts fell by 88%, with the greatest falls occurring among children aged 1-14 years (>90%). Remote contacts more than doubled, increasing most in infants. Total contacts for respiratory illnesses fell by 74% whereas contacts for common non-transmissible conditions shifted largely to remote contacts, mitigating the total fall (31%).
  4. Content Article
    This longitudinal study in BMJ Quality & Safety aimed to examine the impact of nursing team size and composition on inpatient hospital mortality. The authors found that registered nurse staffing and seniority levels were associated with patient mortality. The lack of association for healthcare support workers and agency nurses indicates they are not effective substitutes for registered nurses who regularly work on the ward.
  5. Content Article
    Internationally, safety of care in child and adolescent mental health has received limited attention. Attempts to understand this area have mainly focused on issues of safety in relation to safeguarding on the one hand, or lack of access to services on the other. There is a call for clinicians, service developers and researchers to consider harm and safety more generally in child and adolescent mental health service (CAMHS). America and other countries have begun to initiate discussions on the possibility of harm caused by psychotherapy, however, the lack of shared definitions as to what constitutes safety and harm present ongoing challenges. To start to rise to these challenges this paper, published in Current Treatment Options in Pediatrics, outlines a possible framework for considering harm in relation to child and adolescent mental health provision.
  6. Content Article
    This study, published in BMJ Quality and Safety seeks to determine the association between daily levels of registered nurse (RN) and nursing assistant staffing and hospital mortality.
  7. Content Article
    Electronic health records (EHR) can improve safety via computerised physician order entry with clinical decision support, designed in part to alert providers and prevent potential adverse drug events at entry and before they reach the patient. However, early evidence suggested performance at preventing adverse drug events was mixed. In this study published in BMJ Quality & Safety, Bates et al. used data from 1527 hospitals in the USA from 2009 to 2016 who took a safety performance assessment test using simulated medication orders to test how well their EHR prevented medication errors with potential for patient harm. Results found that the average hospital EHR system correctly prevented only 54.0% of potential adverse drug events tested on the 44-order safety performance assessment in 2009; this rose to 61.6% in 2016. Hospitals that took the assessment multiple times performed better in subsequent years than those taking the test the first time, from 55.2% in the first year of test experience to 70.3% in the eighth, suggesting efforts to participate in voluntary self-assessment and improvement may be helpful in improving medication safety performance. The authors conclude that medication order safety performance has improved over time but is far from perfect. The specifics of EHR medication safety implementation and improvement play a key role in realising the benefits of computerising prescribing, as organisations have substantial latitude in terms of what they implement. Intentional quality improvement efforts appear to be a critical part of high safety performance and may indicate the importance of a culture of safety.
  8. Content Article
    This study assesses the association of increased bed occupancy with changes in the percentage of overnight patients discharged from hospital on a given day and their subsequent 30-day readmission rate. Longitudinal panel data methods are used to analyse secondary care records (n = 4,193,590) for 136 non-specialist Trusts between April 2014 and February 2016.
  9. Content Article
    'The Productive Ward: Releasing time to care' was a quality improvement programme developed by the NHS Institute for Innovation and Improvement (NHSI) and introduced in 2007. It was designed to improve efficiency, productivity and performance at ward level in acute hospitals. It was based on three principles: good ward organisation so that materials were readily accessible displaying ward-level metrics such as patient safety and experience use of visual aids to understand patient status at a glance.
  10. Content Article
    BMJ Quality & Safety, was to determine the association between daily levels of registered nurse (RN) and nursing assistant staffing and hospital mortality.
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