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Found 452 results
  1. News Article
    This week is the MHRA's sixth annual #MedSafetyWeek social media campaign. This year’s campaign theme is reporting suspected side effects following vaccination. This forms part a global effort by national medicines regulatory authorities from over 60 countries and their stakeholders to raise awareness about the importance of reporting. Vaccines are life-saving medicinal products that are given to protect individuals against serious infections and sometimes the most effective way to prevent infectious diseases. The MHRA are calling on all healthcare professionals (HCPs), national immunisation programme staff, as well as patients, their carers and families to report suspected side effects from vaccines or medicines to the MHRA Yellow Card scheme.
  2. News Article
    Mandating COVID-19 vaccinations for all health service staff should be delayed until spring to enable the health service to get through the busy winter period, an NHS leader has urged. Ministers have been considering whether or not to introduce mandatory jabs for all NHS staff in England. Health and social care secretary Sajid Javid said last week he is ‘leaning towards’ making the jabs compulsory as there are about 100,000 NHS workers not fully vaccinated. NHS Providers chief executive Chris Hopson said that if the government was to press ahead, it should delay until April to ensure the NHS can get through the ‘difficult winter’. Plans for mandatory jabs for staff who work or volunteer in care homes in England were announced in June, with an 11 November deadline for staff to have had both doses of vaccine, unless medically exempt. However, Loss of vaccine-hesitant staff may compromise patient safety. Mr Hopson cited cases in Cornwall where NHS staff have been drafted in to help the social care sector. "If we lose large numbers of unvaccinated staff, particularly over the winter period, then that also constitutes a risk to patient safety and quality of care," he told BBC Breakfast. "We know that we’ve got a very, very difficult winter coming up and we know the NHS is going to be absolutely at full stretch. ‘So it makes sense to set the deadline once that winter period has passed. We know that January, February and often early March is very busy, so that’s why we’re saying that an April 2022 deadline is a sensible time.’ Read full story Source: Nursing Standard, 1 November 2021
  3. News Article
    It is coming up to a year since the first mRNA vaccines were approved for use against COVID-19, and almost seven months since they were approved for expectant mothers. The initial government advice was was that they should hold off getting a jab, but since more data has become available, medical experts have been encouraging women to get vaccinated. But there has been no big government awareness campaign, despite pregnant women being identified as a vulnerable group. The proportion of fully vaccinated pregnant women in the UK is as low as 15% (in the US, it is more than twice that, at 33.8%). That such a small porportion of pregnant women are fully vaccinated in the UK, seven months after vaccines were approved for them, is nothing short of a scandal. And more women and their babies are at risk of dying because of it. Recent figures for England show that one in six critically ill patients are unvaccinated pregnant women with Covid. Of the 20 pregnant women requiring the highest level of life-saving care, 19 were unvaccinated and one had received one dose. These are frightening statistics, but on their own they do not seem to be enough to persuade pregnant women to get vaccinated. In order to do that, it’s important to understand why we are seeing such high levels of hesitancy... Read full story Source: The Guardian, 29 October 2021
  4. News Article
    Covid booster jabs are now being given at walk-in clinics in England as the NHS aims to increase vaccine uptake before what is expected to be a challenging winter. From Monday, anyone in an eligible group who had their second dose of a coronavirus vaccine at least six months ago can turn up at one of hundreds of sites to get their top-up without making an appointment. The walk-in centres are also offering vaccinations to 12- to 15-year-olds. The move follows criticism of the booster campaign, with only about half of the 12 million people in England eligible so far for a third vaccine dose having received one. The vaccine rollout to teenagers has lagged behind that of countries including France, Italy and Spain. People entitled to a booster jab are: those aged 50 and over, people who live and work in care homes; frontline health and social care workers; people aged 16 and over with a health condition that puts them at high risk of getting seriously ill from Covid-19; those aged 16 and over who are a main carer for someone at high risk from the virus, and; people aged 16 and over who live with someone who is more likely to get infections. Nikki Kanani, a GP and the deputy lead for the NHS Covid-19 vaccination programme, said: “NHS staff are making it as easy as possible for people to get their top-up vaccination, and from today people can now go online, find their nearest site and go and get their booster without delay. “The booster is not just nice to have. It is really important protection ahead of what we know will be a challenging winter.” Read full story Source: The Guardian, 1 November 2021
  5. News Article
    The agency is now showing disease incidence among unvaccinated people, as well as those who received Johnson & Johnson, Pfizer, and Moderna vaccines. The U.S. Centers for Disease Control and Prevention has published information on its COVID Data Tracker about rates of cases and deaths among fully vaccinated and unvaccinated people. In August, according to the data, unvaccinated people had a 6.1 times greater risk of testing positive for COVID-19, and an 11.3 times greater risk of dying from the disease. Interestingly, the agency also breaks out case and death rates by vaccine product. In mid-August, at the peak of the latest wave, unvaccinated people made up the greatest percentage of COVID-19 cases, at an incident rate of 736.72 cases per 100,000 people. Johnson & Johnson had the second-highest incidence rate, at 171.92 cases per 100,000. Pfizer had the third-highest, at 135.64. And Moderna had the lowest rate, at 86.28 cases per 100,000 people. The death rate mirrored the breakdown in terms of vaccine product and frequency, although the numbers were far lower across the board. Again, at the peak in mid-August, the death rate among unvaccinated people was 13.23 in 100,000 people. Rates for vaccinated people were dramatically reduced, at 3.14, 1.43 and 0.73 for Johnson & Johnson, Pfizer, and Moderna, respectively. When it came to age groups, peak case rates were highest among unvaccinated 12-17 year olds, followed by unvaccinated 30- to 49-year-olds. And 30- to 49-year-olds also had the highest case incidence among vaccinated people when broken down by age group, followed by fully vaccinated 18- to 29-year-olds. Those older than 80 had the highest death rates among both unvaccinated and vaccinated individuals. The COVID Data Tracker site also includes integrated county views, forecasting and hospitalizations by vaccination status. Read the full article here Original source: Healthcare IT News
  6. News Article
    Almost three out of five GPs reported managing patient expectations about vaccinations to be one of the most challenging issues of the pandemic, with multiple changes to vaccine eligibility requirements leaving many people confused and overwhelmed, the president of the Royal Australian College of General Practitioners, Dr Karen Price, said. In her foreword to the college’s Health of the Nation report, published on Thursday, Price said: “Unfortunately, some of these patients took their frustrations out on general practice staff”. “Differing eligibility requirements across jurisdictions added to the strain.” Schools should stay open as greatest risk of Covid transmission is in households, research finds The report is published annually and provides an insight into the state of general practice in Australia. It includes the findings of a survey of 1,386 GPs between April and May, of which 70% were in major cities, 20% inner-regional, 8% outer‐regional, and 2% remote and very remote. Read full story Source: Guardian, 21 October 2021
  7. News Article
    The government’s failure to quickly roll out third doses of the Covid vaccine to clinically vulnerable people and those with weakened immune systems is endangering thousands of lives, patient groups and experts have warned. Immunocompromised individuals currently account for one in 20 Covid patients being admitted to intensive care, according to a new analysis by Blood Cancer UK. These people are less able to mount an immune response after two doses, so are therefore being offered a third to keep them protected. This is separate from the ongoing booster programme, applicable to all over-50s and health care workers. However, a recent Blood Cancer UK survey suggested that less than half of people with blood cancer, who make up about 230,000 of the 500,000 immunocompromised people in the UK, had been invited to receive their third dose by the second week of October. Other clinically vulnerable people have reported struggling to book an appointment via their GP practices after being told by NHS England to come forward for a third vaccine dose. With the situation in Britain reaching a “tipping point”, charities and scientists are fearful the number of immunocompromised in intensive care could further worsen in the weeks to come if they remain unable to access booster jabs. Read full story Source: The Independent, 21 October 2021
  8. News Article
    On Tuesday, there were 356 COVID-19 patients being treated in intensive care wards throughout Australia. Of those, 25 were fully vaccinated. While the data points to the extraordinary efficacy of COVID-19 vaccines in preventing people from becoming severely unwell, being hospitalised and dying, it does raise the question: why do a small number of people become seriously ill and, in rare cases, die, despite being fully vaccinated? An intensive care unit staff specialist at Nepean hospital in Sydney, Dr Nhi Nguyen, said those who are fully vaccinated and die tend to have significant underlying health conditions. Being treated in intensive care, where people may be on a ventilator and unable to move, added to any existing frailty, especially in elderly people, she said. “If we think about intensive care patients in general, whether they are there due to COVID-19, pneumonia or any other infection, we know that those who have underlying disorders, those who are frail, and those with co-morbidities will have a higher risk of dying from whatever the cause of being in intensive care is,” she said. “Being fully vaccinated against Covid protects you from getting severe disease, yes, but it doesn’t completely protect you from getting Covid. So if you are someone with chronic health conditions, what might be a mild disease or mild infection in a young person or a person who is in good health, will have a greater impact on you.” She said this was why the Australian Technical Advisory Group for Immunisation (Atagi) had recommended boosters for those people who are severely immunocompromised. On Wednesday the government said it intended booster shots to be rolled out to the aged care sector within weeks, and to be available to the whole population by the end of the year. Read full story Source: The Guardian, 20 October 2021
  9. News Article
    Scotland's booster jag rollout has hit a major snag after some of the country's most vulnerable people were given half their third vaccine. In total, 140 people who were given their extra dose of the Moderna COVID-19 vaccine in the Gorebridge vaccine centre in Midlothian were affected by the error. Health authorities have maintained there is no risk to individuals due to the error and that half a dose will provide sufficient protection. The individuals affected were all immunosuppressed, the Midlothian Health and Social Care Partnership said, meaning they are more vulnerable to infection and at higher risk from serious complications caused by COVID-19. The Midlothian Health and Social Care Partnership apologised for the mistake and any anxiety caused. Read full story Source: The Scotsman, 19 October 2021
  10. News Article
    Pregnant women are being advised by some health professionals not to have the Covid vaccine despite an edict from the NHS that they should encourage them to get the jab. One in six of the most critically ill Covid patients requiring life-saving care are unvaccinated pregnant women, figures released last week show. Yet messages sent to the Vaccines and Pregnancy helpline, launched on 20 August to help pregnant women navigate information about the vaccine, suggest that some midwives are advising against the jab. One said: “I was initially keen to have the vaccine and then advised by a midwife not to have it.” Another wrote: “I had my first dose before I knew I was pregnant. Now I’m pregnant I’ve been told I’m not allowed my second.” Another reported: “I’ve been advised by midwives not to get the vaccine due to the impact on ovulation and menstruation.” The helpline was set up by the organisation Full Fact in partnership with the campaign group Pregnant Then Screwed. Many of those contacting it complained of conflicting advice while others were pushed from pillar to post. One said: “I’m pregnant and really confused about getting the vaccine. I’ve spoken to my health visitor, who said speak to your GP, the GP said speak to your midwife, and the midwife said they can’t advise me.” Full Fact’s deputy editor, Claire Milne, said the helpline was established to counter misinformation about the vaccine. She explained: “It’s not right so many pregnant women have been left scared for their safety and that of their unborn children. “Messaging around the safety of the vaccines in pregnancy has been, at times, confused. It’s vital that up-to-date information is available – especially when speaking with health professionals.” Read full story Source: The Guardian, 17 October 2021
  11. News Article
    The programme of giving third Covid vaccinations to people with compromised immune systems has been a “chaotic failure”, charities have said, with fewer than half of those eligible contacted about a third jab before an NHS deadline this month. Surveys by Blood Cancer UK and Kidney Care UK found that for both groups of patients, between 55% and 60% had yet to be invited to get a third injection, seen as particularly vital for conditions which affect people’s immune systems, as they are generally less protected by two jabs. The charities said many of those who responded were desperately worried and were struggling to get information about a third vaccination. Some people with blood cancer had resorted to going to vaccination centres without an appointment, pleading for a third dose, Blood Cancer UK said. Official figures show there were 45,066 confirmed new Covid cases in the UK on Thursday, the highest daily total since mid-July. Kidney Care UK said the poor communication highlighted what seemed to be a “woeful lack of preparation” for the programme, the guidance for which was agreed on 2 September. The third dose programme for people with compromised immune systems is separate to the wider rollout of booster jabs being offered to everyone over 50, and others with clinical vulnerabilities, which started on 15 September. Read full story Source: The Guardian, 15 October 2021
  12. News Article
    The Becker's Clinical Leadership & Infection Control editorial team chose the top 10 patient safety issues for healthcare leaders to prioritise in 2021, presented below in no particular order, based on news, study findings and trends reported in the past year. COVID-19 Healthcare staffing shortages Missed and delayed diagnoses Drug and medicine supply shortages Low vaccination coverage and disease resurgance Clinical burnout Health equity Healthcare-associated infections Surgical mistakes Standardising safety efforts. Read full story Source: Becker's Healthcare, 30 December 2020
  13. News Article
    The Pfizer/BioNTech vaccine can still target a key mutation that has emerged in two new variants of coronavirus, laboratory studies show. However, this is only one of many mutations that are found in the new forms of the virus. So while the study has been welcomed, it is not being seen as definitive scientific evidence about how the vaccine will perform. New variants have been detected in the UK and South Africa. Both forms of the virus are spreading more quickly and this has raised questions over what level of protection vaccines can offer against them. The widely held view is that vaccines will still work, but researchers are on the hunt for proof. Read full story Source: BBC News, 8 January 2021
  14. News Article
    The Moderna COVID-19 vaccine has become the third to be approved by the UK. The US pharmaceutical company’s jab was given the green light by Britain’s regulator and doses will be available in the spring. The announcement comes as the rollout of the Pfizer and Oxford vaccines is scaled up to meet Boris Johnson’s target of immunising all care-home patients by the end of the month, with 1,000 vaccination centres expected to be operational by Sunday. The government has also purchased an additional 10 million doses of the Moderna vaccine on top of its previous order of 7 million, taking the total to 17 million. Supplies will begin to be delivered to the UK once Moderna expands its production capability, the Department of Health and Social Care said. The Medicines and Healthcare products Regulatory Agency (MHRA) accepted the recommendation of the Commission on Human Medicines and authorised the Moderna vaccine following months of rigorous clinical trials and extensive analysis of the vaccine’s safety, quality and effectiveness. The jab is 94% effective in preventing disease, including in the elderly. Read full story Source: The Independent, 8 January 2021
  15. News Article
    The government has confirmed plans to open seven new mass vaccination centres across England next week. The seven centres opening are: ExCel Centre (Nightingale), London Etihad Tennis and Football Centre, Manchester Centre for Life, Newcastle Robertson House, Stevenage Epsom Downs racecourse, Surrey Ashton Gate Stadium, Bristol Millennium Point, Birmingham The exact opening dates for each site have yet to be established, however the prime minister’s official spokesperson said they would be opening “next week”. More details on how the vaccination sites will operate are expected to be revealed over the coming days. Read full story Source: The Independent, 6 January 2021
  16. News Article
    In a bid to fight against misinformation about the coronavirus vaccines, a group of scientists from all over the world have created an online guide to building a ‘truth sandwich’. The guide serves to arm people with practical tips, up-to-date information and evidence to talk reliably about the vaccines, and enable them to constructively challenge associated myths. The scientists, led by the University of Bristol, are appealing to everyone to understand the facts set out in the 'COVID-19 Vaccine Communication Handbook', follow the guidance and spread the word. Professor Stephan Lewandowsky, the lead author of the guide, said: “Vaccines are our ticket to freedom and communication about them should be our passport to getting everyone on board." “The way all of us refer to and discuss the COVID-19 vaccines can literally help win the battle against this devastating virus by tackling misinformation and improving uptake, which is crucial." Read full story Source: The Independent, 7 January 2021
  17. News Article
    Doctors on the front line of the UK’s vaccine programme have said they are “ready to go” and will be able to administer doses “very quickly” in the months ahead, amid questions over whether or not the NHS can inoculate 2 million people a week. After suggestions that staffing constraints could hinder the roll-out of the Oxford/AstraZeneca vaccine, which was approved for use last week, NHS officials and GPs have insisted that the health service is primed to deliver doses as soon “as supply becomes available”. On Monday, Professor Stephen Powis, national medical director of NHS England, said 100 hospital hubs and 700 vaccination centres – based in GP practices and other community settings – would have access to the vaccine by the end of the week, with plans in place to expand the programme. “We aim to get it into people’s arms as quickly as it is supplied to us,” Prof Powis said. “If we get 2 million doses a week, our aim is to get 2 million doses into the arms of those priority groups." Read full story Source: The Guardian, 4 January 2021
  18. News Article
    When dentist Andy Bates offered to help administer the coronavirus vaccine, he hadn't bargained for the "overload of bureaucracy" he says came his way. Dr Bates, from North Yorkshire, is one of a number of health staff to criticise the paperwork needed to gain NHS approval to give the jabs. Some medics have been asked for proof they are trained in areas such as preventing radicalisation. The PM said the health secretary would be "taking steps" to address the issue. Asked about reports potential volunteers were being deterred by the additional training and forms about "de-radicalisation measures" and "fire drills", Mr Johnson told the BBC's Andrew Marr on Sunday: "I think it's absurd and I know that the health secretary is taking steps to get rid of that pointless bureaucracy." The NHS has previously said training and checks were needed for vaccinators. Read full story Source: BBC News, 3 January 2021
  19. News Article
    The UK's chief medical officers have defended the Covid vaccination plan, after criticism from a doctors' union. The UK will give both parts of the Oxford and Pfizer vaccines 12 weeks apart, having initially planned to leave 21 days between the Pfizer jabs. The British Medical Association said cancelling patients booked in for their second doses was "grossly unfair". But the chief medical officers said getting more people vaccinated with the first jab "is much more preferable". Pfizer has said it has tested the vaccine's efficacy only when the two vaccines were given up to 21 days apart. But the chief medical officers said the "great majority" of initial protection came from the first jab. "The second vaccine dose is likely to be very important for duration of protection, and at an appropriate dose interval may further increase vaccine efficacy," they said. "In the short term, the additional increase of vaccine efficacy from the second dose is likely to be modest; the great majority of the initial protection from clinical disease is after the first dose of vaccine." Read full story Source: BBC News, 1 January 2021
  20. News Article
    Plans to delay giving the second dose of a Covid vaccine to more than 500,000 people who have received the first jab have caused outcry among doctors who say cancelling appointments wastes time, causes confusion among patients and is potentially unethical. On Wednesday the government announced a change to its Covid vaccination strategy, saying second doses of the newly approved Oxford/AstraZeneca vaccine and the previously approved Pfizer/BioNTech jab would now be given up to 12 weeks after the first dose. The move applies to people scheduled to have their second dose of the Pfizer jab after 4 January, as well as those yet to receive either jab. The government said it hoped the approach would mean as many people as possible soon have some protection against the disease. However, the announcement caused controversy, with Pfizer and BioNTech warning that two doses of their vaccine were required for maximum protection against Covid and that they did not have evidence that the first dose alone offered protection after three weeks. Now doctors have said cancelling appointments for the second dose will take huge amounts of time and could lead to confusion. Read full story Source: The Guardian, 31 December 2020
  21. News Article
    People with allergies and pregnant women can now be given the country’s two approved COVID-19 vaccines, the medical regulator said on Wednesday. Previous advice from the Medicines and Healthcare products Regulatory Agency (MHRA) said people with a range of allergies to food and medicines should not be given the Pfizer vaccine. Dr June Raine, the MHRA’s chief executive, said growing evidence from a pool of at least 800,000 people in the UK and around 1.5 million people in the US who have had the vaccine has "raised no additional concerns". This, she continued, "gives us further assurance that the risk of anaphylaxis can be managed through standard clinical guidance and an observation period following vaccination of at least 15 minutes. Read full story Source: The Independent, 30 December 2020
  22. News Article
    Deaths from COVID-19 in England in the first half of 2021 could exceed those seen in the whole of 2020 unless the vaccination programme is vastly increased and a national lockdown implemented—with educational settings closed for at least a month—researchers have warned. In a preprint released on 24 December, researchers from the London School of Hygiene and Tropical Medicine used modelling to compare the effects of varying COVID-19 restrictions on the virus spread, hospital and intensive care admissions, and deaths from 15 December 2020 to 30 June 2021. The model took account of the new variant spreading rapidly in southern England, which it estimated to be 56% more transmissible than non-variant COVID-19. The study, which has yet to be peer reviewed, said that control measures similar to the November national lockdown would be “unlikely to reduce the effective reproduction number to less than 1, unless primary schools, secondary schools, and universities are also closed.” It added that it would be necessary to “greatly accelerate vaccine rollout to have an appreciable impact in suppressing the resulting disease burden.” Read full story Source: BMJ, 29 December 2020
  23. News Article
    The Oxford-AstraZeneca vaccine has been approved for use in the UK, with the first doses due to be given on Monday amid rising coronavirus cases. The UK has ordered 100 million doses - enough to vaccinate 50 million people. This will cover the entire population, when combined with the full order of the Pfizer-BioNTech jab, Health Secretary Matt Hancock said. It comes as millions more people in England are expected to be placed under the toughest tier four restrictions. On Tuesday, 53,135 new Covid cases were recorded in the UK - the highest single day rise since mass testing began - as well as 414 more deaths within 28 days of a positive test. Read full story Source: BBC News, 30 December 2020
  24. News Article
    All vulnerable people will have been offered a coronavirus vaccination by “late spring” the head of NHS England has said as he warned the health service was “back in the eye of the storm.” In a New Year message, Sir Simon Stevens described 2020 as the “toughest year” and he paid tribute to nurses, doctors, therapists and other NHS staff including hospital cleaners, carers and volunteers as well as care home staff. Sir Simon visited a new vaccination centre on Monday saying: “We think that by late spring with vaccine supplies continuing to come on stream we will have been able to offer all vulnerable people across this country Covid vaccination. That perhaps provides the biggest chink of hope for the year ahead.” His comments came as the NHS in London was said to be “teetering on the edge” as latest data showed the numbers of hospital admissions in the capital jumped more than 200 per cent since the end of lockdown on 2 December. Read full story Source: The Independent, 29 December 2020
  25. News Article
    NHS leaders have raised concerns about the rollout of the coronavirus vaccine, with more than half of hospital trusts and two-thirds of GPs yet to receive supplies amid growing alarm over the new fast-spreading variant. Dr Richard Vautrey, the chair of the British Medical Association’s GP committee, urged the government to speed up delivery of the Pfizer/BioNTech vaccine in order to save lives. Experts also demanded greater transparency from ministers on how many doses are available. Vautrey said: “We need millions of doses to be made available as soon as possible – urgently – because it’s the number one priority for GP practices, our patients and the nation, especially given the new mutant strain. “GPs who haven’t got it yet are frustrated because they want to be getting on and vaccinating their patients as well. Their frustration is understandable. They want to protect their patients, especially their vulnerable patients, as quickly as possible.” Read full story Source: The Guardian, 22 December 2020
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