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Found 545 results
  1. News Article
    A major trial to detect one of the most elusive and deadly cancers - ovarian - has failed to save lives, after two decades of work. The researchers, at University College London, said the results were a disappointment - and thanked the 200,000 people who participated. The trial had looked promising, with annual blood tests detecting cases of ovarian cancer earlier. But routine screening for the cancer is now a distant prospect. Ovarian cancer is tricky to diagnose because the symptoms are easily mistaken for less serious health problems. "Some women are diagnosed so late they are too sick to start treatment," the trial's lead investigator, Prof Usha Menon, said. The UK Collaborative Trial of Ovarian Cancer Screening - the largest in the world - tracked levels of CA125, a chemical released by ovarian tumours, in the blood and sent participants in whom they were rising for an ultrasound scan. Unfortunately the final results, published in the Lancet medical journal, showed the screening had failed to save lives. Read full story Source: BBC News, 12 May 2021
  2. News Article
    A world-leading treatment that halves the risk of lung cancer patients suffering a return of the disease after undergoing treatment, is to be rolled out by NHS England. In a trial of the drug – the first of its kind – around nine out of ten patients treated, remained alive and disease-free after two years – compared to more than four in ten who hadn’t received the new therapy. Lung cancer is the most common cause of cancer death in the UK, accounting for one in five of all cancer deaths. Around 100 patients in England with a rare form of cancer will initially have access to the drug, called Osimertinib, with many more expected to benefit this year. Read full story Source: NHS England, 7 May 2021
  3. News Article
    Blood cancer patients are one of the most vulnerable groups of people at risk of COVID-19, according to research, being 57% more likely to suffer severe disease compared to other cancer patients. Despite the high risk these patients face, charities such as Anthony Nolan, which assist blood cancer patients with finding a stem cell match, were left out of the allocated government budget that was announced in March. The cancellation of face-to-face fundraising and events, despite the increase in demand for services, have led their gross income to be down by an estimated £5.5m for 2021. Henny Braund, chief executive of the charity, said people with blood cancer and blood disorders were “heavily impacted by the pandemic and everyone who needs treatment and support must be able to access it without delay”. Read full story Source: The Independent, 9 May 2021
  4. News Article
    The number of people being diagnosed with cancer early in England has plummeted during the Covid pandemic, sparking fears that many will only be treated when it is too late to save them. Official figures show a third fewer cancers were detected at stage one, when the chances of survival are highest, in the early months of the pandemic than during the same months a year before. Cancer experts fear that the figures, which have been collected by Public Health England’s National Cancer Registration and Analysis Service, mean thousands of people have the disease but have not yet started treatment because of “a shift to later diagnosis”. They urged anyone with possible symptoms of the disease to get them checked out immediately. “While it’s fantastic that Covid rates are dropping and lockdown is easing, the knock-on impact of the pandemic on cancer care cannot be overstated,” said Steven McIntosh, the executive director of advocacy and communications at Macmillan Cancer Support. “We are likely to be dealing with Covid’s long shadow for many years to come.” Read full story Source: The Guardian, 5 May 2021
  5. News Article
    A man who died from lung cancer might have been saved if a hospital trust had not "failed to act" on two abnormal chest X-rays, an investigation found. Growths identified in the patient's examinations were not followed up for three years and were then untreatable, the health ombudsman said. North Cumbria University Hospitals NHS Trust also failed to correctly handle a complaint from the man's daughter. The trust, which runs hospitals in Carlisle and Whitehaven, apologised. The investigation was carried out by the Parliamentary and Health Service Ombudsman (PHSO), which deals with unresolved NHS England complaints. The patient, referred to only as Mr C, was admitted twice to hospital with stroke-like symptoms in 2014 and 2015. On both occasions X-rays were carried out which found abnormal growths in his lungs, but no action was taken. In July 2017, Mr C was found to have advanced lung cancer and he died weeks later. Read full story Source: BBC News, 29 April 2021
  6. News Article
    Fears that their data would be shared with the Home Office following the Windrush scandal left some people from ethnic minorities afraid to access cancer services during the pandemic, an NHS England document has revealed. The paper from the West Midlands Cancer Alliance said there was a “perception” the government was “accelerating immigration removals” and that, as a result, “individuals (particularly those affected by the Windrush scandal) are then fearful of accessing cancer treatment and may not participate in screening programmes for fear their information will be inappropriately shared with the Home Office”. The news comes after figures released last week showed the fall-off in referral and treatment of Black-British patients for cancer during the early stages of the pandemic was sharper than for their White-British counterparts. Referrals and first treatments for cancer dipped across the board in April last year. However, by July, White patients were receiving 77 per cent of the treatment volumes they had done 12 months before. The figure for Black patients was 67 per cent. This 10 percentage point difference continued in August and September, as treatment volumes for White-British patients recovered to 83 and 91 per cent respectively. Parity was achieved from October to December 2020, the latest period for which data is available. Read full story (paywalled) Source: HSJ, 22 April 2021
  7. News Article
    The Covid pandemic is casting a wide shadow over the nation’s health, according to new data revealing a dramatic drop in urgent referrals for suspected cancers in England, and a plummeting quality of life among patients awaiting hip and knee surgery in the UK. The crisis has caused huge disruption to healthcare services: in November NHS England revealed that the number of people waiting more than a year for surgery had reached its highest level since 2008, while patients have reported that their procedures, from cancer surgery to hip replacements, have been repeatedly cancelled. It has also been linked to a fall in MRI and CT scans, while among other consequences breast screening programmes were paused last year. Experts have warned the pandemic may also have led to people avoiding GPs and hospitals, meaning they may have missed out on crucial care. Now an analysis of NHS England data by Cancer Research UK has found that the number of people urgently referred for suspected lung cancer fell by 34% between March 2020 and January 2021 compared with the same time period in 2019/2020 – adjusted for working days. That, they say, equates to about 20,300 fewer people being urgently referred. Declines were also found for other suspected cancers including urological cancer and gynaecological cancer, with about 51,000 fewer patients urgently referred for the former, a 25% drop, and 19,800 fewer patients urgently referred for the latter, a 10% drop, compared with the year before. Read full story Source: The Guardian, 24 March 2021
  8. News Article
    One consequence of an active immune response can be an enlarged lymph node. And, because coronavirus vaccines activate the immune system, some people have swollen nodes in the days following a vaccine. These are harmless if uncomfortable side effects – but they can be misleading when scanned by a radiologist, including during a mammogram. After vaccination, a swollen lymph node may appear as a lump in the armpit. These glands are hotbeds of immune activity, filtering pathogens and storing germ-fighting cells. If you’ve had a sore throat or a cold, there’s a chance you’ve felt a swollen node in your neck. The post-vaccine node may be palpable, too. Any swelling should resolve within days, and if it does, it isn’t a cause for concern. However, should it persist for multiple weeks, then it’s not a bad idea to notify your doctor. Read full story Source: The Independent, 21 March 2021
  9. News Article
    A group of 47 cancer charities says that without urgent action, the UK's cancer death rate will rise for the first time in decades. NHS figures suggest tens of thousands fewer people started cancer treatment since the first lockdown compared to normal times. One Cancer Voice says that the NHS needs more resources. The government says cancer treatment remains a top priority and urges people to see their GP if they have symptoms. Radio 1 Newsbeat has spoken exclusively to One Cancer Voice about the impact of coronavirus on cancer care. The group of charities wants to see more staff available to diagnose and treat cancer, with greater NHS access to private facilities in order to "clear the backlog". "We are calling on the government to invest more money in ensuring the backlog of cancer cases is reduced and eliminated," says Michelle Mitchell, the boss of Cancer Research UK, which heads up One Cancer Voice. "We could face, in this country today, the prospect of cancer survival reducing for the first time in decades. That's why urgent action is required by the government." Read full story Source: BBC News, 16 March 2021
  10. News Article
    NHS England’s cancer director has said it could take another year for the level of cancer treatments and diagnosis carried out to return to normal, after being impeded by COVID-19. National cancer director Dame Cally Palmer told HSJ’s national cancer forum event last week that activity over the past 12 months had been 89% of the previous year, but the service was committed to getting “fully reset” to 2019 levels by March 2022. She shared information showing that, by December 2020, the amount of treatment being carried out following an urgent referral, for most cancers, exceeded December 2019 levels, but that there are still significant treatment backlogs. And, for lung cancer patients, the number of treatments carried out in December 2020 was only 73% of that a year earlier — a decrease from September and October 2020 levels — as covid pressures rose during the third wave. Lung cancer is one of the most amenable to treatment if picked up early. Other areas of diagnostics and treatment have also been severely impeded because of requirements to change practice to reduce the risk of spreading covid, particularly to vulnerable patients. Dame Cally, also chief executive of the Royal Marsden Foundation Trust, said the service was committed to returning to at least normal levels of activity across the board by March next year. Read full story (paywalled) Source: HSJ, 12 March 2021
  11. News Article
    People will be able to check if they have bowel cancer by swallowing a tiny capsule containing miniature cameras, in an extension of patient self-care. In what experts described as a trend towards more NHS at-home care, hastened by the COVID-19 pandemic, thousands of people in England will be able to avoid the discomfort of having a camera inserted into their bowel by instead swallowing a capsule the size of a cod liver oil tablet. Pictures transmitted from inside their body during the painless procedure will help doctors judge whether the person has bowel cancer, the second deadliest form of the disease in the UK. The boss of the NHS in England said the procedure, known as a colon capsule endoscopy, is an example of “sci-fi” medicine increasingly deployed to improve care. One of the country’s top doctors said the capsules illustrated a major shift of healthcare out of hospitals that will see more and more diagnosis and treatment of illness done at home. Prof Martin Marshall, chair of the Royal College of GPs, said: “We’re aware that some patients are reluctant to seek help for certain cancers because the diagnostic tests available can be invasive, so this is a fascinating development and we will be very interested to see the results of the trial. “GPs are preparing for an upsurge in cases of suspected cancer cases post-Covid, and the capsule cameras and new test for cervical cancer are welcome developments that could enable more patients to monitor and manage their own health at home without embarrassment or discomfort.” Read full story Source: The Guardian, 11 March 2021
  12. News Article
    Cancer patients are much less protected against COVID-19 than other people after one dose of the Pfizer vaccine, the first real-world study in this area suggests. With a 12-week wait for the second dose this could leave them vulnerable, says the King's College London and Francis Crick Institute research team. An early second dose appeared to boost cancer patients' protection. Cancer charities are calling for the vaccine strategy to be reviewed. But Cancer Research UK said the small study had not yet been reviewed by other scientists and people undergoing cancer treatment should continue to follow the advice of their doctors. The government said it was focused on "saving lives" and the antibody response "was only part of the protection provided by the vaccine". About 1.2 million people at very high risk of being seriously ill with COVID-19 were prioritised for a first vaccine dose in the first phase of the UK rollout, which includes people with specific cancers. The UK government decided to extend the gap between first and second jabs from three to 12 weeks in late December to give more people some protection as soon as possible. Dr Sheeba Irshad, oncologist and senior study author from King's College London, said the findings were "really worrying" and recommended an urgent review of the timing of doses for people in clinically extremely vulnerable groups. "Until then, it is important that cancer patients continue to observe all public health measures in place such as social distancing and shielding when attending hospitals, even after vaccination," she said. The study, which recruited 205 people, included 151 with solid cancers, such as lung, breast and bowel, or blood cancers. The researchers tested volunteers for antibodies and T-cells in their blood, which signals that the immune system can protect against illness from the virus in the future. Three weeks after one dose, an antibody response was found in 39% of people with solid cancers, 13% of people with blood cancer and 97% of people with no cancer. Following a second dose three weeks after the first, which some cancer patients received, there was a sharp rise in their antibody response against the coronavirus, to 95%. However, among those who had to wait longer for their second dose, there was no real improvement in protection. Read full story Source: BBC News, 11 March 2021
  13. News Article
    A woman is taking legal action against an NHS trust over the “diabolical” and discriminatory treatment of her profoundly deaf husband, who died of cancer in May last year. Susan Kelly, who is also deaf, is angry that her husband, Ronnie, was at no point during two hospital admissions and an outpatient appointment provided with a British Sign Language (BSL) interpreter. Instead, her hearing daughter, Annie Hadfield, was asked to translate his terminal diagnosis, when he was told to “get his affairs in order” and given between two weeks and two months to live, while his wife was left outside the room. He died just over two weeks later at home. Medical staff at Sheffield Teaching Hospitals NHS trust also placed a “do not resuscitate” (DNR) order on Kelly, who had Alzheimer’s disease, during his first hospital admission in late April without either his consent or consulting his wife or daughter. His family found out only after their barrister obtained his hospital notes. Susan Kelly told the Observer through an interpreter: “I didn’t know what DNR meant. I had no idea. I was really shocked. They’d never asked me anything about it. That wasn’t right, it was wrong. Ronnie wouldn’t have known what it meant.” Annie Hadfield added: “I thought it was actually quite diabolical.” The trust is undertaking a review to understand what happened. David Hughes, medical director, said: “We do acknowledge that we have more to do to support patients and relatives who have hearing impairments and it is an area of work we are actively looking at to make improvements.” Read full story Source: The Guardian, 7 March 2021
  14. News Article
    Women aged 70 or over are receiving substandard care to tackle ovarian cancer with one in five patients in their seventies getting no treatment whatsoever, a new study has found. A report from Ovarian Cancer Action revealed almost half of patients in their 70s do not undergo surgery to treat the disease, even though it provides the best long-term prognosis for one of the most common types of cancer in women. In total, around one in five (22%) of ovarian cancer patients aged 70 to 79 and three in five women with ovarian cancer who were over 80 years old were given no treatment for the disease. The inadequate healthcare given to older ovarian cancer patients causes a disproportionately high short term death rate for them, the study found. The study found older patients are substantially less likely to be referred by their GP for diagnostic tests such as ultrasounds when ovarian cancer symptoms surface. Dr Susana Banerjee, a consultant medical oncologist at The Royal Marsden, said: “With an ageing population, many more patients with ovarian cancer are over the age of 70, so there is an urgent need to understand the best way to effectively treat older women." “Optimising patients for treatment through frailty assessments and interventions, sharing best practice across cancer centres and representing older patients in clinical trials are important steps towards ensuring equal access to effective and tolerable treatment that could help more women live beyond their diagnosis, with a good quality of life, no matter their age.”
  15. News Article
    Almost half of people with potential cancer symptoms did not contact their GP during the first wave of the pandemic, a survey suggests. Symptoms left unchecked included coughing up blood, lumps and changes to the appearance of moles. NHS figures showed a fall in referrals to cancer services last spring. However, this study, of almost 8,000 people, captures the fall in people contacting their GP in the first place. The team that carried out the study, from Cardiff University and Cancer Research UK, said this raised concerns that people could be diagnosed later - and so be less likely to be treated successfully and recover. They surveyed a representative sample of people across the UK and found that of 3,025 people who said they had experienced at least one symptom which could be a warning sign of cancer, 45% did not seek help. They also found that: 31% did not seek help after coughing up blood 41% did not seek help for an unexplained lump or swelling 59% did not seek help after noticing changes to the appearance of a mole. Some of the reasons given by people who did not contact their GP were not wanting to waste doctors' time or put extra strain on the NHS; not wanting to be seen as someone who made a fuss; and fear of catching Covid at appointments. But people who did contact their GP reported feeling "safe" and "secure" when attending face-to-face appointments. Read full story Source: BBC News, 25 February 2021
  16. News Article
    About 31,000 women in London are being offered "do-it-at-home" tests to check for early warnings of cervical cancer, as part of an NHS trial. It could be a way to encourage more women to get screened, experts hope. Embarrassment, cultural barriers and worries about Covid, along with many other factors, can stop women going for smear tests at a clinic or GP surgery. Smear-test delays during the pandemic prompted calls for home-screening kits from cervical cancer charities. The swabbing involves using a long, thin cotton bud to take a sample from inside the vagina, which is then sent by post for testing. If the results reveal an infection called human papillomavirus (HPV) they will be invited to their GP for a standard smear test to closely examine the cells of their cervix. Dr Anita Lim, from King's College London, who is leading the YouScreen trial, said: "Women who don't come for regular screening are at the highest risk of developing cervical cancer. "So it is crucial that we find ways like this to make screening easier and protect women from what is a largely preventable cancer. Self-sampling is a game-changer." Read full story Source: BBC News, 24 February 2021
  17. News Article
    Scientists have developed a genetic test to predict whether someone will develop a common type of blood cancer. The breakthrough could lead to potential patients being warned about the risk of progressive Chronic Lymphocytic Leukaemia (CLL) and boost their chances of survival. CLL affects the white blood cells and tends to develop slowly over many years, mostly affecting those aged over 60. By studying blood samples of people with CLL, researchers found they often had the same "genetic tendency" to develop progressive forms of the illness. The team, from eight UK universities and the Institute for Cancer Research, said their work would help doctors "move towards a more personalised diagnosis of leukaemia". Haematology consultant Dr David Allsup, who is also a senior lecturer at Hull York Medical School, said: "Not only does the research inform us if patients have the genetic tendency to develop progressive CLL, but it also enables us to determine whether or not a patient's CLL will require treatment in the future or not." "That way, we are able to keep a close eye on the patients with a high risk, and have treatment options available as soon as they are required." Professor James Allan, from Newcastle University's Centre for Cancer, said: "Emerging evidence suggests that early treatment for patients at high risk of developing progressive CLL could significantly delay the onset of symptomatic leukaemia and improve survival." Read full story Source: The Independent, February 9 F2021
  18. News Article
    A campaign has started to prevent children and young people receiving cancer treatment alone in the pandemic. Charities behind the #Hand2Hold campaign want to enable all young people aged 16 to 25 to be allowed a chaperone, instead of only some. Mikaela Forrester, 18, from Somerset had some of her cancer treatments alone and said she did not want other young people to have that experience. She said without her mother she found it "scary" and "lonely". Miss Forrester lives in Frome and was diagnosed in July 2019 with Stage 2 Hodgkin Lymphoma, an uncommon cancer that develops in the lymphatic system. In March 2020 she was told she had relapsed and would need to undergo a further round of chemotherapy, radiotherapy, and a stem cell transplant. Because of the coronavirus pandemic, she was told she had to have those treatments on her own, without immediate support from her family or friends. She said: "When I had my transplant and my cells harvested with three weeks in hospital, with no visitors, it was just so scary. It was quite lonely." "Even if I could hug my parents, or if they could stand two metres away with a mask on, just knowing they were there during the most difficult times would have made me feel comfortable because it was so overwhelming." Read full story Source: BBC News, 16 February 2021
  19. News Article
    Thousands of lives could be saved if people at risk of developing Britain’s deadliest cancer were screened to diagnose it before it becomes incurable, a major NHS study has found. Giving smokers and ex-smokers a CT scan uncovers cancerous lung tumours when they are at an early enough stage so they can still be removed, rather than continuing to grow unnoticed, it shows. Experts are demanding the government moves to bring in routine CT scanning of smokers and ex-smokers in order to cut the huge death toll from lung cancer. About 48,000 people a year are diagnosed with the disease in the UK and 35,100 die from it – 96 a day. Lung cancer is a particularly brutal form of cancer because it is hard to detect and three out of four cases are diagnosed at stage three or four, when it is already too late to give the person potentially life-saving treatment. However, the Summit study, being run by specialists in the disease at University College London Hospital NHS trust, offers real hope that lung cancer can become a condition that is detected early. CT scanning meant that 70% of the growths detected in people’s lungs were identified when the disease was at stage one or two – a huge increase in the usual rate of early diagnosis. “It’s really a major breakthrough for lung cancer,” Dr Sam Janes of UCLH, the senior investigator of the trial, told the Guardian. "Lung cancer has never had anything that enabled us to detect this devastating cancer earlier and offer curative treatment to this number of lung cancer patients.” Read full story Source: The Guardian, 14 February 2021
  20. News Article
    The backlog of patients who have been waiting for cancer treatment for more than 104 days has more than doubled since last year, according to internal NHS England papers seen by HSJ. At the start of February, the backlog of cases already at more than 15 weeks had hit 6,109, compared to 3,000 at the same point in 2020. National targets state cancer patients should be treated with 62 days of being referred. In the North West region, the backlog has nearly tripled over the same time period, from 289 to 831 (see regional breakdown below). Senior sources told HSJ the increase had been largely driven by acute providers in Greater Manchester and Merseyside. Cases in which patients have to wait more than 104 days for treatment are generally considered serious breaches, and typically trigger a process to identify if the delay has caused harm to the patient. Some local systems have declared a “zero tolerance” for such instances. The data in the papers is provisional. Michelle Mitchell, Cancer Research UK’s chief executive, said the impact of covid-19 on cancer patients has been “devastating”. She added: “The government must urgently make sure the NHS gets the funding it needs to increase cancer service capacity, and give every person with cancer the timely diagnosis and treatment they deserve.” Read full story (paywalled) Source: HSJ, 13 February 2021
  21. News Article
    In a Channel 4 documentary, emergency doctor Dr Ronx asks why more men die of COVID-19? Cancer and HIV too. They also challenge many dangerous gender assumptions in medicine impacting on women's health. View documentary (6 days left)
  22. News Article
    Cancer services at large hospital trust have been at ‘catastrophic’ risk of being overwhelmed, after two of its hospital sites had to suspend life-saving cancer surgeries in the last month due to COVID-19. In its latest board papers Mid and South Essex Foundation Trust rated the “cancellation of cancer elective activity” at its highest risk level of 25 – which based on their own risk-scoring key is “catastrophic”. It said the expected consequences at this risk level include “permanent disability or death, serious irreversible health effects” and an “unacceptable… quality of service”. The trust runs three general acute hospitals in the county. Its 2,000 plus beds make it the third largest trust in England after University Hospitals Birmingham FT and Leeds Teaching Hospitals. The same board papers, dated 28 January, said cancer surgery at Southend University Hospital, one of three hospital sites run by the trust, “ceased on 24 December”. At a second hospital site, Mid Essex Hospital covid “hit hard just before Christmas” and elective work was “dramatically impacted with short period of life and limb only carried out on site”. This meant all P2 cancer surgery — which requires treatment in less than four weeks — did not take place. Both hospital sites said they hoped the independent sector could help them restart cancer surgeries this month with a focus on “long waiting and clinical urgent patients”. It is not clear how much capacity the sector has to work through waiting lists and the board papers said “some of this capacity may be reduced” because of recent changes to a new national contract for the independent sector. Read full story (paywalled) Source: HSJ, 29 January 2021
  23. News Article
    Thousands of women living in the UK suffering from an aggressive type of breast cancer could be helped by a newly identified drug, according to a study. The research, carried out by The Institute of Cancer Research, found medicine presently used to help other breast cancers that have spread to another area of the body, could actually be utilised to help around a fifth of women who have triple negative breast cancer. Around 55,000 women are diagnosed with breast cancer in Britain each year, with approximately one in five of these being triple negative. Younger women and black women are more likely to develop this form of breast cancer which is generally more aggressive. Researchers’ realisation the drug palbociclib could be used far more widely than previously thought could “provide a much-needed targeted treatment” for those who are at higher risk of witnessing their cancer spread more quickly, becoming incurable and often unresponsive to conventional chemotherapy. Dr Simon Vincent, of Breast Cancer Now, a leading charity which funded the study, said: “It’s hugely exciting that this research has uncovered a new possible use for palbociclib as a targeted treatment for some women living with triple negative breast cancer." Read full story Source: The Independent, 28 January 2021
  24. News Article
    There were 800 fewer cancer surgeries in the first two weeks of January than usually take place during the period, according to provisional data seen by HSJ. The bulk of this reduction came in London and the surrounding counties such as Essex, Bedfordshire, and Surrey. London and the south east have been severely hit by coronavirus pressures, causing widely reported mass cancellations of non-urgent elective surgery. However, the impact on cancer cases has, so far, been less clear. NHS England has insisted in the last week that urgent cancer cases should be given the same priority as coronavirus patients. Read full story (paywalled) Source: HSJ, 25 January 2021
  25. News Article
    A care home worker who was wrongly diagnosed with cancer said she thought it was a "cruel joke" when she was told doctors had made a mistake and she did not have cancer at all. Mum-of-four Janice Johnston said her "world crumbled" when she learned she had a rare form of blood cancer at Kent and Canterbury Hospital in 2017. She had 18 months of oral chemotherapy treatment, during which she experienced weight loss, nausea and bone pain, and had to give up her job as an auxiliary nurse. When the treatment did not appear to be working, she says, medics upped the dosage. In 2018, she sought alternative treatment at Guy's Hospital in London. It was there a specialist told her she did not have cancer at all but a different condition. Mrs Johnston was awarded £75,950 in damages after East Kent Hospitals University NHS Foundation Trust admitted liability. Staff at the hospital had failed to do the necessary ultrasound scan and bone marrow biopsy before diagnosing her. Read full story Source: BBC News, 25 January 2021
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