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Found 458 results
  1. News Article
    The NHS is ready to start providing the new coronavirus vaccine "as fast as safely possible", Health Secretary Matt Hancock has said. Asked whether it could be available by Christmas, he said that was "absolutely a possibility" - but he expected the mass roll-out "in the first part of next year". He said vaccination clinics would be open seven days a week, and he was giving GPs an extra £150m. On Monday, early results from the world's first effective coronavirus vaccine showed it could prevent more than 90% of people from getting Covid. The vaccine has been developed by pharmaceutical companies Pfizer and BioNTech and is one of 11 vaccines that are currently in the final stages of testing. The UK has already ordered 40 million doses - enough to vaccinate up to 20 million people as each person will need two doses for it to work effectively. Asked how many people would need to be vaccinated before life can return to normal, Matt Hancock said: "Well the answer to that is we just don't know." "So the trials can tell you if a vaccine is clinically safe and if it's effective at protecting an individual from the disease. What we can't know, until we've vaccinated a significant proportion of the population, is how much it stops the transmission of the disease." Mr Hancock told BBC Radio 4's Today programme it would be "a mammoth logistical operation" and highlighted some of the challenges, including getting it from Belgium to the UK while not removing from a temperature of -70C more than four times. Older care home residents and care home staff are at the top of a list from government scientific advisers of who would get immunised first, followed by health workers. Mr Hancock said NHS staff would go into care homes to vaccinate residents, as well as setting up vaccination venues. Children would not be vaccinated, he said. However, Prof Sir John Bell from Oxford University said: "I would worry about not giving this to as wide a percentage of the population as we can." "I'm more of the view that we need to vaccinate further into the population and vaccinate younger people as well, partly because we don't really know what the long term effects of this disease are." The vaccine will not be released for use until it passes final safety tests and gets the go-ahead from the Medicines and Healthcare products Regulatory Agency. Read full story Source: BBC News, 10 November 2020
  2. News Article
    Pfizer and BioNTech have said that their coronavirus vaccine may be more than 90% effective, after the two pharmaceutical firms released interim data from their ongoing large-scale trial. Preliminary analysis, conducted by an independent data monitoring board, looked at 94 infections recorded so far in the vaccine’s phase 3 study, which has enrolled nearly 44,000 people in the US and five other countries. Of those participants who were infected with COVID-19, it is currently unclear how many had received the vaccine versus those who had been given a placebo. The current efficacy rate, which is much better than most experts expected, implies that no more than eight volunteers will have been inoculated. The data have yet to be peer-reviewed, and Pfizer said the initial protection rate might change by the time the study ends. The longevity of the immune response provoked by the mRNA-based vaccine also remains unknown. However, the findings are the most promising indication to date that a vaccine will be effective in preventing disease among infected individuals, handing humanity a crucial tool in tackling the pandemic. Pfizer and its German partner BioTech will continue with the phase 3 trial until 164 infections have been reported among volunteers - a figure that will give regulatory authorities a clearer idea of the vaccine’s efficacy. This number is expected to be reached by early December in light of the rising US infection rates, Pfizer said. The two companies said they have so far found no serious safety concerns and expect to seek US emergency use authorisation later this month. Read full story Source: The Independent, 9 November 2020
  3. News Article
    The NHS has erroneously written to thousands of patients who have had glandular fever in the past asking them to get a flu jab from their GP. The error left some GPs with practice phone lines blocked last week while reception staff have had to explain to patients they are not actually eligible for free flu vaccination. Nearly 40,000 letters were sent out to patients with a past history indicating glandular fever because of a coding error at NHS Digital. This was meant to identify patients with suppressed immune systems which would include those who currently have glandular fever and encourage them to contact their GP practice to arrange vaccination. However, the historical cases were not excluded, leading to the letters being automatically generated even when the glandular fever diagnosis was decades old. When NHS Digital realised the error, it contacted NHS England – which was responsible for posting out the letters – and managed to stop others being sent out. An NHS Digital spokesman said: “During a process to identify patients eligible for a flu vaccination, glandular fever was incorrectly included in a complex list of conditions that cause persistent immunosuppression. This led to some patients incorrectly receiving a letter encouraging them to seek a flu vaccination. “There has been no adverse clinical impact for patients and the issue was quickly resolved before the majority of letters were sent.” NHSD said patients who had received the letter would receive another one to explain and to reassure them." Read full story (paywalled) Source: HSJ, 4 November 2020
  4. News Article
    Levels of protective antibodies in people wane "quite rapidly" after coronavirus infection, say researchers. Antibodies are a key part of our immune defences and stop the virus from getting inside the body's cells. The Imperial College London team found the number of people testing positive for antibodies has fallen by 26% between June and September. They say immunity appears to be fading and there is a risk of catching the virus multiple times. More than 350,000 people in England have taken an antibody test as part of the REACT-2 study so far. In the first round of testing, at the end of June and the beginning of July, about 60 in 1,000 people had detectable antibodies. But in the latest set of tests, in September, only 44 per 1,000 people were positive. "Immunity is waning quite rapidly, we're only three months after our first [round of tests] and we're already showing a 26% decline in antibodies," said Prof Helen Ward, one of the researchers. The fall was greater in those over 65, compared with younger age groups, and in those without symptoms compared with those with full-blown COVID-19. The number of healthcare workers with antibodies remained relatively high, which the researchers suggest may be due to regular exposure to the virus. There have been very few confirmed cases of people getting Covid twice. However, the researchers warn this may be due to immunity only just starting to fade since the peak infection rates of March and April. The hope is the second infection will be milder than the first, even if immunity does decline, as the body should have an "immune memory" of the first encounter and know how to fight back. The researchers say their findings do not scupper hopes of a vaccine, which may prove more effective than a real infection. One of the researchers, Prof Graham Cooke, said: "The big picture is after the first wave, the great majority of the country didn't have evidence of protective immunity. The need for a vaccine is still very large, the data doesn't change that." Read full story Source: BBC News, 27 October 2020
  5. News Article
    A wider range of healthcare workers—including midwives, paramedics, physiotherapists, and pharmacists—are now allowed to give flu and potentially COVID-19 vaccines after the introduction of new laws by the UK government. The changes to the Human Medicines Regulations 2012, first proposed in August1 and consulted upon last month, came into effect on 16 October. The Department of Health and Social Care said that the expanded workforce will have to undergo additional training to ensure patient safety. It added that government planning will “ensure this does not affect other services in hospitals and in GP and community services, by drawing on a pool of experienced NHS professionals through the NHS Bring Back Scheme.” Commenting on the changes, England’s deputy chief medical officer Jonathan Van-Tam said, “The measures outlined today aim to improve access and strengthen existing safeguards protecting patients.” Read full story Source: BMJ, 16 October 2020
  6. News Article
    All pregnant women have been urged by doctors to get a free flu vaccination this winter to ensure they and their babies are protected. People can get infected with flu and coronavirus at the same time - with Public Health England finding if you get both simultaneously you may get more seriously ill. Researchers previously said those who have been infected with both viruses face a serious increase to their risk of death and warned the public “not to be complacent” in the wake of fears flu could circulate around the country alongside COVID-19. The Royal College of Obstetricians and Gynaecologists (RCOG) and Royal College of Midwives note while getting flu is not a big deal for most people, getting the virus while you are pregnant can be serious for a small proportion of women and their babies. Flu can occasionally lead to stillbirth, maternal death and raise the chances of having a miscarriage. Dr Edward Morris, president of RCOG, said: “We are keen to reassure pregnant women that flu vaccination is safe for women to have at any stage in pregnancy - from the first few weeks right up to their due date, and while breastfeeding." "Over the last 10 years, the flu vaccine has been routinely and safely offered to pregnant women in the UK. The vaccine can also pass some protection to babies, which lasts for the first months of their lives." Read full story Source: The Independent, 12 October 2020
  7. News Article
    GP surgeries are waiting up to a month for supplies of this winter’s flu vaccine amid unprecedented numbers of patients seeking jabs ahead of the second wave of COVID-19, family doctors have said. The Royal College of GPs (RCPG) has written to the health secretary, Matt Hancock, seeking assurances that they will have enough doses of the vaccine to cope with demand. The struggle to get jabs has prompted fears that vulnerable groups, including elderly people and those with underlying conditions, will go unprotected. “We have heard anecdotally that some surgeries are waiting up to a month for replenished supplies of vaccine, which raises concerns that there are significant distribution problems,” Prof Martin Marshall, the RCGP’s chair and a family doctor in London, said in the letter. One GP in Nottingham said there had been “a huge uptake compared to previous years, well over what we anticipated” at their surgery among groups eligible for the free jab, “so supplies ran out quickly”. “The next delivery is several weeks away and there are patients in at-risk groups who are having to wait. We have a patient aged 70 with heart disease who wants the vaccine but we currently have none to give her until the next delivery in mid to late October,” the GP said. Shortages mean that people aged 50 to 64, who are being offered a jab for the first time on the NHS, may have to wait until those with a greater medical need have been immunised first. Read full story Source: The Guardian, 4 October 2020
  8. News Article
    Less than half of the UK population will get a Covid vaccine with the elderly being top priority - a top advisor has warned. Kate Bingham, who was appointed as the chair of the Vaccine Taskforce back in May has claimed that the public has been “misguided” when it comes to availability of a vaccine. In an interview with the Financial Times, she said the government “needs to vaccinate everyone at risk”. She said: “People keep talking about ‘time to vaccinate the whole population’, but that is misguided." “There’s going to be no vaccination of people under 18. It’s an adult-only vaccine, for people over 50, focusing on health workers and carehome workers and the vulnerable.” Read full story Source: Financial Times, 4 October 2020
  9. News Article
    Experts say robust legal protections are needed to inspire public confidence. The UK government has set out plans to amend drug regulations in case it decides that COVID-19 vaccines should be used before they are licensed, in a bid to roll them out more quickly. In a consultation on the proposals that ran from 28 August to 18 September the Department of Health and Social Care for England explained that if a suitable vaccine emerged with strong evidence of safety, quality, and efficacy the government would seek to license it through the usual route but could supply it in the meantime. The document added, “A COVID-19 vaccine would only be authorised in this way if the UK’s licensing authority was satisfied that there is sufficient evidence to demonstrate the safety, quality, and efficacy of the vaccine. ‘Unlicensed’ does not mean ‘untested.” The consultation, and the timeframe in which it was conducted, prompted some people to post their concerns on social media. However, the Human Medicine Regulations 2012 already allow the licensing authority to temporarily authorise the supply of an unlicensed product in response to certain public health threats, including the suspected spread of pathogens. The proposed change would allow conditions to be attached “to ensure product safety, quality, and efficacy” The 2012 regulations also give healthcare professionals and manufacturers immunity from being sued in the civil courts for the use of some unlicensed products recommended by the licensing authority in response to a public health threat. The new regulations would extend the immunity to drug companies that have not manufactured the product but placed it on the market with the approval of the licensing authority, and they clarify the consequences for a breach of conditions imposed by the authority. Social media posts play into existing concerns that many people might not accept the vaccine, as surveys indicate. Lawyers have told the Department for Health and Social Care that to inspire public confidence it must provide redress for the few people who might experience adverse effects. Bozena Michalowska, a partner specialising in product liability at the law firm Leigh Day, said, “I do not believe that people will want to play Russian roulette with their health by taking a vaccine which they know nothing about, especially when they know that the risks they take are just taken by them and not a shared risk and they will not have sufficient protection should things go wrong.” Read full story Source: The BMJ, 28 September 2020
  10. News Article
    Having flu and COVID-19 together significantly increases your risk of death, say government scientists who are urging all those at risk of getting or transmitting flu to get the vaccine in the coming weeks and months. The evidence for the double whammy is currently limited and comes mostly from a study with small numbers – 58 people – carried out in the UK during the early phase of the pandemic. “As I understand it, it’s 43% of those with co-infection died compared with 26.9% of those who tested positive for Covid only,” said England’s deputy chief medical officer, Prof Jonathan Van-Tam. These were people who had been hospitalised and had been tested for both viruses, he said, and so were very ill – but the rate of death from Covid alone in the study between January and April was similar to the known rate of Covid hospital mortality generally of around 25% or 26%. "I think it is the relative difference in size of those rates that’s rather more important than the absolute rate,” he said. The study may have been small and they would be doing further studies this season, but the findings tallied with other work that has been done, he said. “If you get both, you are in some serious trouble, and the people who are most likely to get both of these infections may be the very people who can least afford to in terms of their own immune system, or their risk for serious outcomes. So please protect yourself against flu, this year,” says said Prof Yvonne Doyle, medical director of Public Health England The government has bought 30,000,000 doses of flu vaccine, which is more than ever before. They will arrive in batches, so the elderly – over 65 – and those with medical conditions will be called for immunisation first. Relatives of those who are on the shielding list will also be called up. The letters will begin to go out this week. Because of the threat of Covid and the risk that people with flu could be infected if admitted to hospital, all those aged 50-64 will be offered flu vaccination, but not straight away. They should wait to be called by their GP. Read full story Source: The Guardian, 22 September 2020
  11. News Article
    Pregnant women are struggling to get the coronavirus vaccine because clinics are unable to guarantee they will have the right type of jab available, Labour MP Stella Creasy has said. The Pfizer-BioNTech or Moderna jabs are preferable for pregnant women because there is more safety data available. But the online booking system in England does not allow them to specify which vaccine they require. Pregnant women are advised to speak to their GP instead of booking online. But Ms Creasy, 44, said GPs do not always know when local vaccination centres will have specific types of the jab available. The MP for Walthamstow, who is currently pregnant with her second child, said she had received five invitations to be vaccinated but she could not take them up because there is no system to specify she needs the Pfizer or Moderna jab. "I don't think it's been made enough of a priority because there's a presumption it will become more of a priority as they move through the age groups, which is a misreading of the data about pregnancy," she told the BBC. Read full story Source: BBC News, 7 May 2021
  12. News Article
    Two doses of the Pfizer-BioNTech vaccine can provide more than 95% protection against infection, severe illness and death from Covid, according to a groundbreaking study in Israel. The middle eastern country currently leads the world in its inoculation programme, with more than half (56 per cent) of its population having already received both doses of the Pfizer vaccine. The research, published today in The Lancet journal, also concluded that a single dose of the jab provides 58 per cent protection against infection, 76% against hospital admission, and 77% against death. The researchers said their study highlights the importance of fully vaccinating adults against the virus but acknowledged challenges remain to get the pandemic under control – including uncertainty around how long immunity lasts, from both vaccines and natural infection, and the emergence of variants that may be resistant to jabs currently on the market. Read full story Source: The Independent, 6 May 2021
  13. News Article
    Younger adults are particularly affected by the rare blood clotting disorder linked to the Oxford-AstraZeneca vaccine, the UK's medicines regulator has said. The Medicines and Healthcare products Regulatory Agency (MHRA) said there were 209 cases in the UK of the rare combination of blood clots with low platelet counts following being vaccinated the Oxford-AstraZeneca jab, with 41 deaths, up to 21 April. This is up from 168 cases and 32 deaths the previous week. The new data also shows 24 cases of clots in people aged 18 to 29, 28 in those in their thirties, 30 in people in their forties, 59 in people in their fifties and 57 in those aged 60 and above, with the age not known in the remaining cases. The numbers appear to rise with age but that is because more older people have been vaccinated. Fewer than one in five clots was fatal. The latest NHS England data show that 5.5 million people under 45 had received a first dose by 25 April, while 22.6 million of those 45 and over had done so. MHRA chief executive June Raine said no medicine or vaccine was without risk, but that blood clots were extremely rare. She added: “The benefits of the vaccine continue to outweigh the risks for most people. It is still vitally important that people come forward for their vaccination when invited to do so." Read full story Source: The Independent, 3 May 2021
  14. News Article
    The vaccination rate for staff at older care homes is below the recommended level set by scientists in more than half of England’s local authorities, analysis of NHS England data has revealed. Data as of 18 April shows that 76 out of 149 LAs had not reached the 80% vaccination threshold for care home staff to provide a minimum level of protection against COVID-19, according to the PA news agency. In 17 areas, less than 70% of staff had received a first jab. Lambeth, where 23 cases of a South African COVID variant have been recently reported in a care home, had the lowest uptake at 52.4%. The government last week announced the launch of a five-week consultation on mandatory staff vaccination as a result of the failure in some areas to reach the designated threshold. Read full story Source: Care Home Professional. 23 April 2021
  15. News Article
    Pregnant women should be offered a Covid jab when other people their age get one, the UK's vaccine advisers say. They say the Pfizer and Moderna vaccines are preferable because data from the US in 90,000 pregnant women has not raised any safety concerns. Up until now, only women with underlying health conditions or those whose risk of exposure to the virus was high were eligible. The shift in advice brings the UK into line with other countries. The Joint Committee on Vaccination and Immunisation now advises that pregnant women should all be offered the Pfizer-BioNTech or Moderna vaccines where available, at the same time as the rest of the population. They are encouraged to discuss the risks and benefits of the vaccines with their doctor before making the appointment, but it is not a requirement. "There is no evidence to suggest that other vaccines are unsafe for pregnant women, but more research is needed," it added. Currently, there is a lack of data on the AstraZeneca vaccine in pregnancy because pregnant women were not included in trials, but the JCVI says more evidence may be forthcoming in the near future. Read full story Source: BBC News, 17 April 2021
  16. News Article
    A group of royal colleges has produced guidance for doctors seeing patients who have concerns about symptoms after receiving the Oxford AstraZeneca COVID-19 vaccine. The Royal College of Emergency Medicine, the Society for Acute Medicine, and the Royal College of Physicians say that anyone who presents with symptoms suggestive of COVID-19 vaccine induced thrombosis and thrombocytopenia (VITT)1 should have a full blood count to check their platelet level. Symptoms of concern include persistent or severe headaches, seizures, or focal neurology; shortness of breath, persistent chest, or abdominal pain; and swelling, redness, pallor, or cold lower limbs. The advice comes after the HSJ reported that emergency clinicians had raised concerns over a surge in patients attending emergency departments as a result of anxiety over the safety of the AstraZeneca vaccine. Investigations by EU and UK regulators into reports of unusual blood clots after receiving the vaccine concluded that these are a “possible” and “extremely rare” side effect. Katherine Henderson, president of the Royal College of Emergency Medicine, said that following the announcements, patients had been attending emergency departments after receiving the AstraZeneca vaccine. “I saw 21 patients with concerns in an eight hour shift, so we have to have a way of dealing with this. It was important for us to have a strategy for managing those patients that didn’t mean that they were getting over-investigated but they were getting reassurance. We also need to be aware that if somebody has significant symptoms it is always possible, given the rarity of VITT, that it is something else,” she said. Read full story Source: BMJ, 13 April 2021
  17. News Article
    Emergency clinicians have raised concerns and called for central guidance for dealing with a rush of unnecessary A&E attendances triggered by health anxiety over the Oxford covid vaccine’s safety. HSJ has heard from numerous emergency clinicians who reported an increasing number of attendances from people with very mild symptoms, such as headaches, but who were concerned they might be having a potentially serious reaction to the Oxford-AstraZeneca jab. The reports have come from London, the Midlands, the South, the North West and the East of England. Some expressed concerns about the impact of increased attendances on already busy accident and emergency departments. Senior staff said patients were self-presenting at A&E and at their GPs. HSJ has also been told some emergency departments have been alarmed by the number of patients presenting with mild symptoms who said they were told to go to A&E by their GPs. The concerns follow the announcement by government and regulators earlier this week that under-30s should be offered different covid vaccines where they are available, because of uncertain evidence of a very small risk of serious blood clotting linked to the Oxford/Az jab. Read full story (paywalled) Source: HSJ, 9 April 2021
  18. News Article
    Women need more information about contraceptive options, experts said, after concerns over rare blood clots linked to the AstraZeneca Covid jab prompted a debate over side-effects caused by certain forms of the pill. On Wednesday the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) said that evidence that the jab could be causing a rare blood clotting syndrome was growing stronger. As a result the UK’s Joint Committee on Vaccination and Immunisation (JCVI) recommended that healthy people under the age of 30 who were at low risk of Covid should be offered a different vaccine if possible. But the announcement prompted numerous posts on social media questioning why there had been little comment on combined hormonal contraceptives. These methods, which include certain pills, vaginal rings and patches, contain forms of oestrogen and progesterone hormones and have been associated with increased risk of clots, including deep vein thrombosis, pulmonary embolism and cerebral venous sinus thrombosis (CVST) – a very rare clot on the brain. Speaking on ITV’s Good Morning Britain Adam Finn, a professor who is part of the JCVI, confirmed the difference in risk. “The risks of thrombosis that come with taking the pill are very much higher than the risks that we were just seeing on those slides [relating to the rare blood clots from the AstraZeneca vaccine],” he said. Read full story Source: The Guardian, 9 April 2021
  19. News Article
    Increasingly strong evidence shows that the UK's vaccination programme is breaking the link between COVID-19 cases and deaths, scientists tracking the epidemic have said. A study found infections had fallen by roughly two-thirds since February, before beginning to level off. This is probably because people are beginning to mix more - but deaths have not followed the same pattern. This was not the case before January, when the vaccine rollout began. The research, commissioned by the government and run by Imperial College London, is based on swabs taken from 140,000 people selected to represent England's population. Of that group, who were tested for the virus between 11 and 30 March, 227 had a positive result, giving a rate of 0.2%, or one in 500 people. But in people over the age of 65, the infection rate was half that with one in 1,000 people testing positive for Covid. Read full story Source: BBC News, 8 April 2021
  20. News Article
    GPs should only give the Oxford/AstraZeneca Covid vaccine to patients with medical conditions which put them at higher risk of developing blood clots if the benefits outweigh the risks, the UK medicines regulator has said. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued the advice to healthcare professionals regarding while it continues to review a link between the vaccine and rare blood clots. It has also added to previous advice regarding symptoms for patients to look out for following their Covid vaccination with the AZ vaccine. The new advice from the MHRA said: Administration of Covid-19 Vaccine AstraZeneca in people of any age who are at higher risk of blood clots because of their medical condition should be considered only if benefits from the protection from COVID-19 infection outweighs potential risks. Anyone who experienced cerebral or other major blood clots occurring with low levels of platelets after their first vaccine dose of Covid-19 Vaccine AstraZeneca should not have their second dose. Anyone who did not have these side effects should come forward for their second dose when invited. Pregnancy predisposes to thrombosis, therefore women should discuss with their healthcare professional whether the benefits of having the vaccine outweigh the risks for them. Meanwhile, ‘anyone who has symptoms four days or more after vaccination is advised to seek prompt medical advice’. These include: a new onset of severe or persistent headache, blurred vision, confusion or seizures develop shortness of breath, chest pain, leg swelling or persistent abdominal pain, unusual skin bruising or pinpoint round spots beyond the injection site. Read full story Source: Pulse, 7 April 2021
  21. News Article
    An estimated 10% to 30% of people who get COVID-19 suffer from lingering symptoms of the disease, or what's known as "long COVID." Judy Dodd, who lives in New York City, is one of them. She spent nearly a year plagued by headaches, shortness of breath, extreme fatigue and problems with smell, among other symptoms. She says she worried that this "slog through life" was going to be her new normal. Everything changed after she got her COVID-19 vaccine. "I was like a new person, it was the craziest thing ever," says Dodd, referring to how many of her health problems subsided significantly after her second shot. And she's not alone. As the U.S. pushes to get people vaccinated, a curious benefit is emerging for those with this post-illness syndrome: Their symptoms are easing and, in some cases, fully resolving after they get vaccinated. Judy Dodd suffered lingering symptoms of COVID-19 for nearly a year, until she got her vaccine. It's the latest clue in the immunological puzzle of long COVID, a still poorly understood condition that leaves some who get infected with wide-ranging symptoms months after the initial illness. The notion that a vaccine aimed at preventing the disease may also be a treatment has sparked optimism among patients, and scientists who study the post-illness syndrome are taking a close look at these stories. Read full story Source: NPR, 31 March 2021
  22. News Article
    People aged 16 or over who live with immunosuppressed adults should be prioritised for COVID-19 vaccination alongside priority group 6 (people aged 16 to 65 who have a clinical condition that puts them at higher risk), the UK government’s vaccine advisory committee has said. This would include people living in households with an adult who has a weakened immune system, such as those with blood cancer or HIV, or people on immunosuppressive treatment, including chemotherapy, the Joint Committee on Vaccination and Immunisation (JCVI) said. These people are not only more likely to have poorer outcomes after SARS-CoV-2 infection but may not respond as well to the vaccine as others, recent evidence indicates, said the JCVI. The committee said it had made the new recommendation after evidence emerged showing that the covid-19 vaccines may reduce transmission, meaning that vaccinating those around immunosuppressed individuals could help reduce their risk of infection. The JCVI’s chair of COVID-19 immunisations, Wei Shen Lim, said, “The vaccination programme has so far seen high vaccine uptake and very encouraging results on infection rates, hospitalisations, and mortality. Yet we know that the vaccine isn’t as effective in those who are immunosuppressed. Our latest advice will help reduce the risk of infection in those who may not be able to fully benefit from being vaccinated themselves.” Read full story Source: BMJ, 29 March 2021
  23. News Article
    Tens of thousands of post-operative deaths could be avoided by ensuring patients are given coronavirus vaccines while waiting for elective surgery, a new study suggests. People awaiting surgery around the globe should thus be prioritised for COVID-19 jabs ahead of other groups, according to the research, funded by the National Institute for Health Research (NIHR). Studying data for 141,582 patients from across 1,667 hospitals in 116 countries – including Australia, Brazil, China, India, UAE, the UK and the US, scientists found that between 0.6 and 1.6% of patients have developed coronavirus in the wake of elective surgery. For patients who did contract COVID-19, their risk of death was four to eight times greater than typically seen in the 30 days after surgery. Given the higher risks that surgical patients face, scientists calculate that vaccines are more likely to have a life-saving impact upon pre-operative patients – particularly the over-70s and cancer patients – than among the general population. The researchers estimated that – in order to save one life in the course of a year – 351 people aged over 70 facing cancer surgery required vaccination. This figure rises to 1,840 among over-70s in general. “Pre-operative vaccination could support a safe restart of elective surgery by significantly reducing the risk of Covid-19 complications in patients and preventing tens of thousands of Covid-19-related post-operative deaths,” said co-lead author Aneel Bhangu, from the University of Birmingham. Read full story Source: The Independent, 25 March 2021
  24. News Article
    Care home workers in England could be legally required to have a COVID-19 vaccination under plans being considered by the government. According to details of a paper submitted to the COVID-19 operations cabinet subcommittee last week and leaked to the Telegraph, the prime minister, Boris Johnson, and the health secretary, Matt Hancock, have agreed to the proposal in order to protect vulnerable residents. The move would prove highly controversial and could result in legal challenges. The cabinet subcommittee paper warned a large number of social care workers may quit if the change is made, and said that lawsuits on human rights grounds could be possible. A government spokesman insisted “no final decisions have been made” but did not rule out jabs being made compulsory for care workers. The government is also reviewing the introduction of vaccination passports. Read full story Source: The Guardian, 22 March 2021
  25. News Article
    One consequence of an active immune response can be an enlarged lymph node. And, because coronavirus vaccines activate the immune system, some people have swollen nodes in the days following a vaccine. These are harmless if uncomfortable side effects – but they can be misleading when scanned by a radiologist, including during a mammogram. After vaccination, a swollen lymph node may appear as a lump in the armpit. These glands are hotbeds of immune activity, filtering pathogens and storing germ-fighting cells. If you’ve had a sore throat or a cold, there’s a chance you’ve felt a swollen node in your neck. The post-vaccine node may be palpable, too. Any swelling should resolve within days, and if it does, it isn’t a cause for concern. However, should it persist for multiple weeks, then it’s not a bad idea to notify your doctor. Read full story Source: The Independent, 21 March 2021
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