Stress from racism and deprivation could explain why black women are more likely to die during childbirth, a study has found.
Researchers reviewed 44 existing studies that examined three physiological pathways associated with worse pregnancy outcomes: oxidative stress, inflammation, and uteroplacental vascular resistance, and found black women had higher levels of the three metrics.
Such physiological differences are not the result of genetic differences, according to the researchers, but rather suggest that socioenvironmental stressors such as systemic racism and deprivation, which are known to have a measurable biological effect, may influence the body’s ability to function healthily during pregnancy.
Grace Amedor, of the University of Cambridge, the first author of the peer-reviewed study published in the journal Trends in Endocrinology and Metabolism, said: “Pregnancy and childbirth put great stress on a woman’s body. Black women may experience additional strain due to factors including systemic racism, socioeconomic disadvantage and environmental stressors.
“During pregnancy, this strain may affect key biological processes in ways that increase the risk of conditions such as pre-eclampsia. I was surprised that although this disparity had been known for a long time, there was little research into the potential underlying physiological reasons.
“It’s important that we don’t stop trying to tackle the root causes that lead to worse pregnancy outcomes in black women, which are the socioeconomic disparities and the systemic racism they can experience throughout their lives.”
Source: The Guardian, 29 April 2026
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