MHRA Safety Roundup: February 2026

Summary

The Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines, medical devices and blood components for transfusion in the UK. This roundup provides a summary of their latest safety advice for medicines and medical device users. It includes details of medicine recalls, medical device field safety notices and details of how to report drug reactions and device incidents.

Content

This month's Safety Roundup includes: 

• Drug Safety Update on Falsified Mounjaro KwikPen 15mg pre-filled pens 
• Drug Safety Update on Semaglutide (Wegovy, Ozempic and Rybelsus): risk of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) 
• Drug Safety Update on IXCHIQ Chikungunya vaccine: updates to restrictions of use following safety review 
• Drug Safety Update on GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases 
• Letters, medicines recalls and device notifications sent to healthcare professionals in February 2026  
• News and guidance on:
  • UKHSA and MHRA issue reminder to healthcare professionals regarding use of non-sterile alcohol-free wipes 
  • Updates to instructions for use (IFUs) of Cardinal Health Chest Drainage Units & accessories 
  • Respiratory tube connector: risk of patient harm due to manufacturing defect 
  • Medical devices regulations: targeted consultation on the indefinite recognition of CE marked devices