Asthma research disadvantages women by disregarding sex hormones

Women with asthma are twice as likely to die from an asthma attack compared with men in the UK, new figures show as health experts called for urgent research into the condition’s sex-related differences.

They are more likely to have the condition, more likely to need hospital treatment for it and more likely to die from an attack, Asthma + Lung UK said. Over the past five years women have accounted for more than two-thirds of asthma deaths in the UK.

The charity said the current “one size fits all” approach to asthma treatment is “not working” because it does not take into account the impact that female sex hormones during puberty, periods, pregnancy and menopause can have on asthma symptoms and attacks. More must be done to tackle the “stark health inequality”, it added.

Between 2014-15 and 2019-20 more than 5,100 women in the UK died from an asthma attack compared with fewer than 2,300 men. Meanwhile, emergency hospital admissions in England show that, among those aged 20 to 49, women were 2.5 times more likely to be admitted to hospital for asthma treatment compared with men.

Asthma + Lung UK said many people were unaware that fluctuations in female sex hormones can cause asthma symptoms to flare up or even trigger life-threatening attacks. It is calling for more research to examine the sex-related differences in asthma.

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Source: The Guardian, 27 April 2022