MHRA Safety Roundup: November 2025

Summary

The Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines, medical devices and blood components for transfusion in the UK. This roundup provides a summary of their latest safety advice for medicines and medical device users. It includes details of medicine recalls, medical device field safety notices and details of how to report drug reactions and device incidents.

Content

This month's Safety Roundup includes:

• Letters, medicines recalls and device notifications sent to healthcare professionals in November 2025 

News and guidance on:

• Reported Cases of Patient Deaths Among Duchenne Muscular Dystrophy Patients Receiving Duvyzat®▼ (givinostat) and reminder of risk mitigation measures 
• Tamoxifen: update to product information on QT prolongation and monitoring recommendations for high-risk patients 
• MHRA begins hosting Patient Safety Commissioner