MHRA Safety Roundup: August 2026

Summary

The Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines, medical devices and blood components for transfusion in the UK. This roundup provides a summary of their latest safety advice for medicines and medical device users. It includes details of medicine recalls, medical device field safety notices and details of how to report drug reactions and device incidents.

Content

This month's Safety Roundup includes:

• National Patient Safety Alert on ResMed Astral 100 and 150 Ventilators: Potential for Patient Harm due to Unexpected Interruption of Ventilation Therapy (NatPSA/2026/004/MHRA)

• Device Safety Information on Dräger Atlan Anaesthesia workstations: risk of ventilator failure (DSI/2026/005)

• Device Safety Information on Belzer UW® Cold Storage Solution and Belzer MPS® (UW Machine Perfusion Solution): manufactured by Carnamedica (UKRP: Bridge to Life): Updated advice on the contamination of fluid DSI/2026/006 (update to DSI/2023/005)

• Device Safety Information on Devices supplied without valid UKCA/CE conformity markings or certification: remove from use and place in quarantine (DSI/2026/007)

• Device Safety Information on Rectal catheters sold for personal use (gas and colic relievers): Do not use in infants, including for the treatment of colic, gas-related discomfort or constipation (DSI/2026/008)

• Device Safety Information on NGPod pH testing device: quarantine and dispose of all devices (DSI/2026/009)

• Letters, medicines recalls and device notifications sent to healthcare professionals in August 2026 

• News and guidance on: 

  • Increased liver monitoring for sotorasib (Lumykras▼) patients with recent immunotherapy

  • Elranatamab: risk of progressive multifocal leukoencephalopathy

  • Updated MHRA guidance on point of care testing