USA: Taking Tylenol during pregnancy has no link to autism, new study finds

Taking acetaminophen – known in the US by the brand name Tylenol – during pregnancy has no effect on later autism diagnoses, according to a sweeping new study from Denmark published on Monday.

The Trump administration has targeted Tylenol use in pregnancy as a major cause of autism in children, which appears to have led to a drop in pregnant people taking the pain reliever.

Health officials announced in September 2025 that the US Food and Drug Administration (FDA) would initiate a label change for acetaminophen, warning of a potential link to autism. Trump cautioned several times against taking the pain reliever during pregnancy.

“If you’re pregnant, don’t take Tylenol,” Trump said at a press conference at the time. “Don’t take Tylenol. Don’t have your baby take Tylenol.” He said the medication was “not good” and taking Tylenol during pregnancy was associated with “a very increased risk of autism”.

Through Denmark’s robust national healthcare system, researchers were able to track more than 1.5 million children ‌born between 1997 and 2022 in the national health registry, including 31,098 children who were exposed to Tylenol in utero.

Autism was diagnosed in 1.8% of children who were exposed to Tylenol and 3% of those who weren’t, according to the study, which was published in Jama Pediatrics. A similar 2024 study in Sweden found a marginal link that disappeared after taking siblings into account, suggesting that autism is strongly genetic, which has already been demonstrated in other studies.

Tylenol is safe to take during pregnancy and can play a key role in relieving pain and bringing down fevers. Yet after the September announcement, Tylenol orders for pregnant women in emergency rooms dropped by 16% in the initial study period, according to a Lancet study published last month.

Health officials’ “words are affecting behavior”, said Jeremy Faust, a co-author of that Lancet study, an emergency physician at Mass General Brigham and a health services researcher at Harvard Medical School.

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Source: The Guardian, 13 April 2026