People in Britain with heart failure are being given larger doses of drugs at the start of their treatment after a global study found that this led to a huge fall in deaths.
Experts say the new approach could mean those with the potentially fatal condition start receiving their ideal amount of medication within two weeks of diagnosis rather than after many months.
Evidence from other countries that have already used the treatment found it cut deaths from heart failure by 62% and lowered their risk of ending up back in hospital by 30%.
St George’s hospital in London and Morriston hospital in Swansea have begun treating patients with the innovative method, which those involved say “is a total gamechanger” for the condition.
Clinical staff likened the approach – known as “rapid titration” – to how cancer patients are given a full dose of chemotherapy medication from the start of their treatment to improve their chances of recovery.
“Heart failure is a silent killer, so this new way of treating patients is a total gamechanger that I never thought I’d see in my lifetime. It will save many lives and bring hope to so many families,” said Matthew Sunter, the lead heart failure nurse at St George’s.
“In days gone by, we would start patients on a very low dose and increase it by very small doses. It could take nine to 12 months to reach the optimal dose.
“Strong-HF has allowed us to think completely differently. For the first time ever, we offer patients a review one week after discharge and we can catch them before they get sick enough to need to come back into hospital.
“And we can get them on to the recommended therapy for their heart failure within two to three weeks instead of nine to 12 months.”
Source: The Guardian, 16 April 2025
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