‘Life-changing’ therapy now available for cystic fibrosis patients

Hundreds of people with cystic fibrosis are to be offered a new pill which has been hailed as “life changing” by health experts.

The National Institute for Health and Care Excellence (NICE) has given the green light for the NHS to give patients Alyftrek, a type of modulator therapy which works to tackle the underlying cause of cystic fibrosis (CF).

CF is caused by a faulty gene that affects the production of a protein called CFTR.

Modulator drugs work by helping to make the CFTR protein work effectively.

Helen Knight, director of medicines evaluation at NICE, said: “CFTR modulators are already revolutionising the way cystic fibrosis is treated so we’re pleased to be able to recommend Alyftrek, the latest of this type of treatment that has been shown to be effective, with significant benefits for people with the condition.”

Read full story

Source: The Independent, 15 July 2025