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Found 193 results
  1. Content Article
    Official data on whooping cough show that reports of suspected cases are at a 15-year high in the first three months of 2024. This article in the Pharmaceutical Journal looks at why cases are increasing, including falling rates of children receiving the childhood 6-in-1 vaccine and maternal vaccination. It outlines the symptoms of whooping cough, describes how it can be treated and includes a map identifying infection 'hot spots' in England and Wales. This article is free to read but you will need to sign up for a free Pharmaceutical Journal online account.
  2. Content Article
    About 1 in 5 people who have had chickenpox develop shingles, predominantly those who are over 70. However, uptake rates of the shingles vaccine are falling in London and across England. The purpose of this toolkit is to help GPs better protect their patients by suggesting ways to improve uptake of the shingles vaccine. These suggestions are based on best practice and evidence and have been shown to work with little or no cost to practices.
  3. News Article
    Shortly before Joseph Ladapo was sworn in as Florida’s surgeon general in 2022, the New Yorker ran a short column welcoming the vaccine-skeptic doctor to his new role, and highlighting his advocacy for the use of leeches in public health. It was satire of course, a teasing of the Harvard-educated physician for his unorthodox medical views, which include a steadfast belief that life-saving Covid shots are the work of the devil, and that opening a window is the preferred treatment for the inhalation of toxic fumes from gas stoves. But now, with an entirely preventable outbreak of measles spreading across Florida, medical experts are questioning if quackery really has become official health policy in the nation’s third most-populous state. As the highly contagious disease raged in a Broward county elementary school, Ladapo, a politically appointed acolyte of Florida’s far-right governor Ron DeSantis, wrote to parents telling them it was perfectly fine for parents to continue to send in their unvaccinated children. “The surgeon general is Ron DeSantis’s lapdog, and says whatever DeSantis wants him to say,” said Dr Robert Speth, a professor of pharmaceutical sciences at south Florida’s Nova Southeastern University with more than four decades of research experience. “His statements are more political than medical and that’s a horrible disservice to the citizens of Florida. He’s somebody whose job is to protect public health, and he’s doing the exact opposite.” Read full story (paywalled) Source: Guardian, 3 March 2024
  4. News Article
    Mothers of babies who died or suffered brain damage from a Group B Strep (GBS) infection say routine screening is needed. Oliver Plumb, from the charity Group B Strep Support, said it was a "small number of babies" exposed to the bacteria that developed a serious and potentially fatal infection. He said around 800 babies a year developed the infection - which is about two babies a day - and about one a week will die, while another a week will be left with a lifelong disability. "It's a heart-breaking start to life for families and that often the first they hear of Group B Strep is when their baby is sick or in intensive care". The charity has called for GBS to be a notifiable disease to make it a legal responsibility for infections to be reported. It added that current figures could be "missing around one fifth of the infections". There was a "postcode lottery" in terms of how many families will hear about GBS, he said. The charity also backed calls for screening. "In the UK we don't sadly have a routine testing programme, that's at odds with much of the rest of the high-income world. " A DHSC spokesperson said a public consultation on the notifiable diseases list was carried out last year. "DHSC and UKHSA are considering the responses and confirmation of any changes will be published in due course," they said. Several reasons for not recommending routine screening have been given by the committee, including that results can change in the last few weeks of labour, and that GBS does not cause infection in every baby. Read full story Source: BBC News, 26 February 2024 Further reading on the hub: Leading for safety: A conversation with Jane Plumb, Founder of Group B Strep Support
  5. Content Article
    England is well on the way towards its goal of eliminating hepatitis C; with over 84,000 patients treated and cleared, there are now more people that have been treated than are left to treat. However, there are still up to an estimated 70,000 people left to find—and what has worked to find patients so far, might not work so well for those that remain to be found. This is where former patients, also known as peers, come in. In this blog, Hepatitis C Trust CEO Rachel Halford and Mark Gillyon-Powell, Head of programme for hepatitis C at NHS England, look at how patient engagement has been essential to efforts to eliminate Hepatitis C in England.
  6. News Article
    Potentially deadly fungal infections with Candida auris are spreading rapidly in US healthcare facilities, with cases nearly doubling between 2020 and 2021, the US Centers for Disease Control and Prevention has said. The number of cases rose by 44% to 476 in 2019, up from 330 in 2018, and subsequently by 59% to 756 in 2020 and by an additional 95% to 1,471 in 2021, the agency’s researchers reported on Monday in Annals of Internal Medicine. Also concerning was a tripling in 2021 of the number of cases that were resistant to echinocandins, the class of drugs most often recommended for treatment of the disease. The most common Candida auris symptoms include a high fever and chills that do not improve after antibiotic treatment for suspected bacterial infections, according to guidelines from the CDC. Additional symptoms can develop if the infection spreads. Dr Waleed Javaid – an epidemiologist, infectious disease expert and director of infection prevention and control at New York’s Mount Sinai Downtown – told NBC News that the new findings were “worrisome”. Read full story Source: The Guardian, 21 March 2023
  7. News Article
    About 2 million people die a year as a result of a core group of fungi, and the WHO is concerned we are unprepared for the future. In October, the World Health Organization released its fungal priority pathogens list, the first global effort to create a mycological “most wanted” list of the 19 fungi most dangerous to humans . “Despite posing a growing threat to human health, fungal infections receive very little attention and resources globally,” the report said. “This all makes it impossible to estimate the exact burden of fungal infections, and consequently difficult to galvanise policy and programmatic action.” Fungi are the most populous life form on the planet, with an estimated 12 million species existing worldwide. Only a fraction of these species infect humans, but they are responsible for roughly a billion infections each year. “Most of those are superficial things like athlete’s foot, that no one’s particularly bothered about, but there is a core group that causes life-threatening infections, and particularly in susceptible populations such as the very old or young, and those with immune systems that don’t work properly,” says Mark Ramsdale, an associate professor of mycology at the MRC Centre for Medical Mycology in Exeter. About 1.5 million people die a year as a result of these infections, says Ramsdale – although that may be an underestimation, because fungi predominantly infect people who already have major health problems. “The primary cause of death will probably be leukaemia or heart transplant, or whatever,” he says. “But the thing that actually kills the patient is a fungal infection, so there is a strong element of underreporting going on.” Underestimating them would be a mistake. Read full story Source: The Guardian, 10 February 2023
  8. News Article
    The extent of the gridlock in hospitals over Christmas has been revealed, with data in England showing record numbers of ambulances delayed dropping off patients at A&E. More than 40% of crews were forced to wait at least half an hour to hand over patients in the week up to 1 January. That is the highest level since records began a decade ago. But there is hope pressures could soon start easing, with flu and Covid admissions dropping last week. But the UK Health Security Agency is warning it is too early to say whether the flu season - the worst in a decade - has peaked, because reporting lags over the festive period may have affected the data. And Matthew Taylor, of the NHS Confederation, which represents hospitals, said wards were still incredibly full, which was creating delays in A&E and for ambulances. He said hospitals were facing "crisis conditions" that were presenting a risk to patients. Read full story Source: BBC News, 5 January 2023
  9. News Article
    People have been urged to wear face coverings and remain at home if feeling unwell, as an already crisis-stricken NHS faces down multiple waves of winter illnesses. With children returning to school at a time when high levels of flu, Covid-19 and scarlet fever are all being reported, the UK Health Security Agency (UKHSA) has issued fresh guidance in a bid to minimise the diseases’ spread. Parents have been urged to keep children at home if they are unwell and have a fever, with adults told to only go out if necessary and wear face coverings if they are ill and avoid visiting vulnerable people. While transport secretary Mark Harper said the advice was “very sensible”, Downing Street insisted that such guidance was “pretty longstanding”, stressing that it was “not mandatory” and remained a far cry from ministers “telling people what to do” at the height of the pandemic. The government has also reintroduced travel bans for those testing positive for Covid-19 in China from 5 January amid a mass outbreak there. It comes as pressure on the NHS continues to grow, but Rishi Sunak said he was “confident” the NHS has the funding it needs despite accusations from senior doctors his government is in denial about the scale of the crisis in the health service. Read full story Source: The Independent, 3 January 2023
  10. News Article
    Flu and Covid are on the rise in England, with experts stressing the importance of vaccination and warning that people who feel unwell should stay at home rather than mingling with others during the festive season. The figures come as cases of scarlet fever and strep A infections continue to rise. The UK Health Security Agency (UKHSA) added that while invasive strep A infections remain rare there have now been a total of 94 deaths in England, including 21 children. Dr Colin Brown, the deputy director at UKHSA, sought to reassure parents. “I understand how this large rise in scarlet fever and ‘strep throat’ may be concerning to parents, however the condition can be easily treated with antibiotics and it is very rare that a child will go on to become more seriously ill,” he said, adding that parents should visit NHS.UK, contact 111 online or their GP surgery if their child has symptoms so they can be assessed for treatment. Dr Mary Ramsay, the director of public health programmes at UKHSA, noted a link between indoor mixing and the rise in cases and hospital admissions for flu and Covid. “Both Covid and flu can cause severe illness or even death for those most vulnerable in our communities, and so it is also important to avoid contact with other people if you are unwell in order to help stop infections spreading over the Christmas and new year period,” she said. Read full story Source: The Guardian, 23 December 2022
  11. News Article
    The number of suspected scarlet fever cases since September has risen to nearly 30,000 after the UK Health Security Agency added almost 10,000 potential new infections in the last week. More than 27,000 people could have had infections since 12 September, according to the UKHSA, who revealed on Tuesday that there were more cases than first thought because of the “significant rise” in infections. The figures come from medical practitioners referring suspected cases to the local authority or health protection team. A total of 16 children aged under 18 have died from invasive group A streptococcus (iGAS), otherwise known as strep A. Parents are advised to contact 111 or a GP surgery if a child has symptoms. They can also include nausea and vomiting. New serious shortage protocols were issued to pharmacists last week in an attempt to help those experiencing supply issues with penicillin. Chemists had widely reported problems getting hold of liquid penicillin and amoxycillin due to the increase in demand. The antibiotics are often prescribed for children who have scarlet fever or strep A. People in the industry have also reported rising prices. Pharmacists are now able to prescribe an alternative antibiotic or formulation of penicillin, such as tablets. Read full story Source: The Guardian, 20 December 2022
  12. News Article
    Flu hospitalisations in England have jumped by more than 40 per cent in a week as the NHS braces for one of the worst outbreaks of the virus in recent years. Analysis of NHS data by The Telegraph shows that rates are more than eight times higher than expected at this time of year. On the current trajectory, admissions next week could pass the peak of the 2017-18 outbreak – one of the worst of the last 20 years – which led to nearly 30,000 deaths. Flu hospitalisations are so high that they have overtaken Covid admissions for the first time since the start of the pandemic. The rise could not come at a worse time for the NHS. It is already suffering the biggest treatment backlog in its history, which is set to be exacerbated by strikes by nurses and ambulance paramedics. Read full story Source: The Telegraph, 15 December 2022
  13. News Article
    Three more children have died from strep A, it has emerged, and pharmacists in the UK have been told they can supply alternative antibiotics to those originally prescribed, in a bid to ease shortages of certain forms of penicillin. The UK Health Security Agency (UKHSA) data shows at least 19 children have now died across the UK, while there are 7,750 cases of scarlet fever so far this season. This is more than treble the 2,538 at the same point in the year during the last comparably high season in 2017 to 2018. The Department of Health and Social Care (DHSC) has issued serious shortage protocols (SSPs) for three penicillin medicines amid increased demand for the antibiotics. Pharmacists and GPs in the UK have faced serious difficulties in securing supplies of penicillin and amoxycillin, antibiotics used to treat infections including strep A. As a result, parents have reported having to visit a string of pharmacies to obtain medicines prescribed for their sick children, while the price of some antibiotics has risen sharply – a situation pharmacists say has left them facing losses. The health minister Will Quince said: “The increased demand for the antibiotics prescribed to treat strep A has meant some pharmacists have been unable to supply the medicine shown on the prescription. “These serious shortage protocols will allow pharmacists to supply an alternative form of penicillin, which will make things easier for them, patients, and GPs. “We are taking decisive action to address these temporary issues and improve access to these medicines by continuing to work with manufacturers and wholesalers to speed up deliveries, bring forward stock they have to help ensure it gets to where it’s needed, and boost supply to meet demand as quickly as possible.” Read full story Source: The Guardian, 15 December 2022
  14. News Article
    Pharmacists say supplies of key antibiotics to treat strep A have "gone from bad to worse" in the past week. The Association of Independent Multiple Pharmacies (AIMP) said the situation was "unacceptable" and it was time for the government to get a plan in place. Four antibiotics, which treat different conditions, have been added to a list of products that the UK cannot export. The UK government says it is working urgently with manufacturers and wholesalers to speed up deliveries. However, Leyla Hannbeck, chief executive of the AIMP, which represents 4,000 pharmacies in the UK, said the supply of antibiotics to treat bacterial infections including strep A and scarlet fever was "very poor". She said the problem had been highlighted a week ago, but it was now getting worse, making it very difficult to get hold of any antibiotics. "People are having to go from one pharmacy to another - it's chaos," she said. "Supplies are not coming through to us and it feels like no-one cares." Read full story Source: BBC News, 14 December 2022
  15. News Article
    The family of a boy who died of an invasive form of strep A have said they sought medical help three times before he was admitted to hospital. Jax Albert Jefferys, who attended Morelands Primary School in Waterlooville, Hampshire, died on 1 December, aged five. His family said they were initially told he had flu. Since September, UK Health Security Agency figures show 15 UK children have died after invasive strep A infections. Paying tribute to their "darling son", Jax's family said they had sought medical advice on three occasions during the four days leading up to his death and were told that he was suffering with influenza A. "We then followed the recommended course of action: to administer a proprietary paracetamol-based medication in the prescribed dosage," they said in a statement. However, they said on the fourth day Jax's condition "deteriorated so much" they "rushed him to hospital" and he later died. "Only after his death was it confirmed that the cause was [strep A]," the family said. Read full story Source: BBC News, 14 December 2022
  16. News Article
    Strep A home-testing kits have sold out online as parents rush to find ways to diagnose their children’s rashes and high temperatures. The panic-buying follows the deaths of at least 16 children from invasive strep A infections in the UK. As infections and deaths from strep A have risen over the past few weeks, parents have turned to tests that involve a long cotton swab that is lightly passed over the back of the throat. Solutions and a strip test are then used to display results. These tests are now being sold online for more than £100, while some retailers have reported selling out after demand soared over the past few days. Other suppliers have warned customers that they will not be able to get hold of a test until after Christmas. One online retailer told customers that they would not be able to get the products until mid-January. Others said they were awaiting deliveries but “there may be delays beyond our control”. Strep A tests are not sold in England through the NHS because the National Institute for Health and Care Excellence (NICE) – which approves and advises on clinical care – has said their accuracy is uncertain and likely to be “highly variable”. Scotland has not approved them either, though in Wales people can buy them over the counter for £7.50. “We’re not advising using those [tests] for the time being,” Professor Kamila Hawthorne, chair of the Royal College of GPs, said on Friday. “It is a clinical diagnosis. It is not too difficult to make. So long as the parent watches their child and brings their child in, then we are more than happy to see them.” Read full story Source: The Guardian, 11 December 2022
  17. News Article
    GP leaders have urged the government to put out clearer advice for parents about when to seek help over potential strep A infections. Prof Kamila Hawthorne, of the Royal College of GPs, said many surgeries were struggling with the extra demand on top of existing pressures. The government should consider "overspill" services for surgeries unable to cope, she said. Since September, 15 UK children have died after invasive strep A infections. This includes the death of one child in Wales, and one in Northern Ireland. There have been no deaths confirmed in Scotland. The UK Health Security Agency figures (UKHSA) show there have also been 47 deaths from strep A in adults in England. Most strep A infections are mild, but more severe invasive cases - while still rare - are rising. Prof Hawthorne, said: "We do not want to discourage patients who are worried about their children to seek medical attention, particularly given the current circumstances. "But we do want to see good public health messaging across the UK, making it clear to parents when they should seek help and the different care options available to them - as well as when they don't need to seek medical attention." Read full story Source: BBC News, 8 December 2022
  18. News Article
    Antibiotics could be given to children at schools affected by Strep A to stop the spread of the infection, schools minister Nick Gibb has said. Mr Gibb told Sky News that the UK Health and Security Agency (UKHSA) is "working closely with the schools involved and giving very specific advice to those schools which may involve the use of penicillin". He added that health officials will "have more to say about that". "They're providing more general advice to parents, which is to look out for the symptoms - so, sore throat, fever, high temperature and also a red or raised rash on the skin are symptoms of this invasive Strep A outbreak." His comments came after the ninth death of a child from the infection. Read full story Source: Sky News, 6 December 2022
  19. News Article
    ‘Rubbish’ communications on Group A Strep from government agencies made A&Es more ‘risky’ over the weekend, after services were flooded with the ‘worried well’, several senior provider sources have told HSJ. On Friday the UK Health Security Agency, successor to Public Health England, issued a warning on a higher than usual number of cases after the deaths of five children under 10 in a week. Several senior sources in hospital, 111/ambulance, urgent care and primary care providers, told HSJ they were not warned UKHSA were making an announcement that would also see services flooded by the worried well. NHS England’s clinical lead for integrated urgent care issued a letter, seen by HSJ, saying a “considerable increase” in 111 demand over the weekend was “in part due to Group A Strep concerns”. Sources in the sector said the increase in demand was “heavily” Strep-related. One senior accident and emergency leader told HSJ that when parents could not get through on 111 they brought their children to emergency departments. “The media messaging has been handled terribly”, they added. They added: “Huge numbers of ‘worried well’ makes the A&E a much more dangerous place. We are just not equipped to deal with the volume of patients. [There is a] much greater chance we would miss one seriously unwell child when we are wading through a six-hour queue of viral, but otherwise well, kids.” Read full story (paywalled) Source: HSJ, 6 December 2022
  20. News Article
    There have been five recorded deaths within seven days of an invasive Strep A diagnosis in children under 10 in England this season, the UK Health Security Agency has said. A child under the age of 10 has also died in Wales after contracting the infection. Group A strep bacteria can cause many infections, ranging from minor illnesses to deadly diseases, but serious complications and deaths are rare. According to UKHSA data, there were 2.3 cases of invasive disease per 100,000 children aged one to four this year in England, compared with an average of 0.5 in the pre-pandemic seasons (2017 to 2019). There have also been 1.1 cases per 100,000 children aged five to nine, compared with the pre-pandemic average of 0.3 (2017 to 2019). The UKHSA said investigations are under way following reports of an increase in lower respiratory tract Group A Strep infections in children over the past few weeks, which have caused severe illness. It added that there is no evidence to suggest a new strain of Strep A is circulating, and the increase is most likely related to high amounts of circulating bacteria and social mixing. Read full story Source: Sky News, 3 December 2022
  21. News Article
    There is now an "imminent threat" of measles spreading in every region of the world, the World Health Organisation and the US public health agency has said. In a joint report, the health organisations said there had been a fall in vaccines against measles and less surveillance of the disease during the COVID pandemic. Measles is one of the most contagious human viruses but is almost entirely preventable through vaccination, though it requires 95% vaccine coverage to prevent outbreaks. A record high of nearly 40 million children missed a dose last year because of hurdles created by the pandemic, according to the report by the WHO and the US Centers for Disease Control and Prevention. This has left millions of children susceptible to the disease. "We are at a crossroads," Patrick O'Connor, the WHO's measles lead, said. "It is going to be a very challenging 12-24 months trying to mitigate this." Read full story Source: Sky News, 24 November 2022
  22. Content Article
    Antimicrobial resistance (AMR) is a major challenge to the UK’s health security, and is already responsible for a significant burden of death, disability and prolonged illness globally. The growing resistance of bacteria, viruses and fungi to the drugs commonly used to treat them threatens modern medicine, and our ability to carry out standard medical procedures. This report draws on the expert input of a roundtable held by public service think tank Reform in October 2022, to assess progress made against proposals published by Reform in 2020.
  23. News Article
    A new treatment to protect babies against a common and potentially dangerous winter virus has been approved by the Medicines and Healthcare products Regulatory Agency (MHRA). Respiratory syncytial virus (RSV) is the main reason children under five end up in hospital. In a normal winter, RSV mostly causes coughs and colds which clear up in a couple of weeks - but it can be particularly serious in infants under the age of two, causing severe lung problems such as bronchiolitis and pneumonia. Every year, about 29,000 babies need hospital care for RSV and most have no other health issues beforehand. The new antibody treatment, called nirsevimab, from Sanofi and AstraZeneca, has already been shown to reduce lower respiratory tract infections caused by RSV by 74.5% in trials involving 4,000 babies. It works by preventing RSV from fusing to cells in the respiratory tract and causing infections. But it still needs more research in larger numbers of babies before it can be used on the NHS. Researchers now plan to investigate whether it can cut the number of babies needing hospital care for RSV, and are urging parents to sign up to their study. The study is open to newborn babies and those up to 12 months old. Only one visit for the antibody injection is needed, and follow-up sessions happen via an app. Co-study leader Dr Simon Drysdale, consultant paediatrician in infectious diseases at London's St George's Hospital, said the treatment could eventually be given at birth to offer protection for the first months of life, or during routine immunisations at two months old. Read full story Source: 10 November 2022
  24. News Article
    The health board in the Scottish Borders has said it is monitoring "unseasonably high" numbers of scarlet fever cases in the region. Parents have been asked to be aware of the symptoms so that early treatment with antibiotics can be given. Scarlet fever is a bacterial illness that mainly affects children under 10 but people of any age can get it. NHS Borders said it would usually clear up after about a week but anyone who thinks they or a child may have it has been asked to contact a GP for a proper diagnosis and appropriate treatment. "Due to the contagious nature of scarlet fever, if you or your child has the illness, please stay at home for at least 24 hours after starting treatment with antibiotics," it added. Read full story Source: BBC News, 7 November 2022
  25. News Article
    A case of MRSA has been reported at the congested asylum processing centre at Manston in Kent, the Guardian has learned, after it emerged that Suella Braverman ignored advice that people were being kept at the centre unlawfully. The antibiotic-resistant bacteria was identified in an asylum seeker who initially tested positive for diphtheria. But the asylum seeker was moved out of the site in Ramsgate to a hotel hundreds of miles away before the positive test result was received, raising concerns about the spread of the infection. The Manston site is understood to now have at least eight confirmed cases of diphtheria, a highly contagious and potentially serious bacterial infection. Migrants are meant to be held at the short-term holding facility, which opened in January, for 24 hours while they undergo checks before being moved into immigration detention centres or asylum accommodation such as a hotel. But giving evidence to a committee of MPs last week, David Neal, the independent chief inspector of borders and immigration, said he had spoken to a family from Afghanistan living in a marquee for 32 days, and two families from Iraq and Syria sleeping on mats with blankets for two weeks. Conditions at the site left him “speechless”, he said. On a visit to the site on 24 October, Neal was told there were four confirmed cases of diphtheria. Protective medical equipment for staff has now been brought on to the site. Although diphtheria is a notifiable disease, meaning cases must be reported to authorities, those at Manston have not appeared on weekly public health reports. A Home Office spokesperson said it was “aware of a very small number of cases of diphtheria reported at Manston”, and that proper medical guidance and protocols were being followed. Read full story Source: The Guardian, 30 October 2022
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