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Found 14 results
  1. News Article
    Home test kits for a virus which attacks the liver are now available to order online in England, as the NHS tries to reach those needing treatment. Hepatitis C tends to affect current or past drug users and people who have had contact with infected blood through a tattoo or medical procedure abroad. It can lead to liver disease and cancer, but symptoms often go unnoticed for many years. The NHS website says it can usually be cured by taking a course of tablets. More than 70,000 people are thought to be living with the virus in England. Some may not know they have it, so would be unlikely to go to their GP for a test. Read full story Source: BBC News, 13 May 2023
  2. News Article
    The NHS is set to eliminate hepatitis C in England by 2025 due to targeted screening campaigns for those at risk and effective drug treatments, according to health officials. NHS England said the measures are helping to dramatically cut deaths from the virus five years ahead of global targets. Deaths from hepatitis C – including liver disease and cancer – have fallen by 35% since NHS England struck a five-year deal worth almost £1bn to buy antiviral drugs for thousands of patients in 2018. The World Health Organization’s target of a 10% reduction in hepatitis C-related death by 2020 has been exceeded threefold in England. An NHS screening programme launched in September is also enabling up to 80,000 people unknowingly living with the disease to get a diagnosis and treatment sooner by searching health records for key risk factors, such as historic blood transfusions or HIV. Prof Sir Stephen Powis, NHS England’s national medical director, said the health service was “leading the world” in the drive to save lives and eliminate hepatitis C while also tackling health inequalities. He said: “Thanks to targeted screening and because the NHS has a proven track record of striking medicine agreements that give patients access to the latest drugs, we are on track to beat global targets and become the first country to eliminate hepatitis C.” Read full story Source: The Guardian, 28 December 2022
  3. Content Article
    On 3 September 2021 assistant coroner Jonathan Stevens commenced an investigation into the death of Martha Mills, aged 13 years. Martha sustained a handlebar injury whilst cycling on a family holiday in Wales. She was transferred to King’s College Hospital London and died approximately one month later. Her medical cause of death was: 1a refractory shock 1b sepsis 1c pancreatic transection (operated) 1d abdominal trauma.
  4. News Article
    The NHS is to use artificial intelligence to detect, screen and treat people at risk of hepatitis C under plans to eradicate the disease by 2030. Hepatitis C often does not have any noticeable symptoms until the liver has been severely damaged, which means thousands of people are living with the infection – known as the silent killer – without realising it. Left untreated, it can cause life-threatening damage to the liver over years. But with modern treatments now available, it is possible to cure the infection. Now health chiefs are launching a hi-tech screening programme in England in a fresh drive to identify thousands of people unaware they have the virus. The scheme, due to begin in the next few weeks, aims to help people living with hepatitis C get a life-saving diagnosis and access to treatment before it is too late. The NHS will identify people who may have the virus by using AI to scan health records for a number of key risk factors, such as historical blood transfusions or an HIV diagnosis. Anyone identified through the new screening process will be invited for a review by their GP and, if appropriate, further screening for hepatitis C. Those who test positive for the virus will be offered treatment available after NHS England struck a deal with three major pharmaceutical companies. Prof Graham Foster, national clinical chair for NHS England’s hepatitis C elimination programmes, said the scheme “marks a significant step forward” in the fight to eliminate the virus before 2030. It will “use new software to identify and test patients most at risk from the virus – potentially saving thousands of lives”, he added. Read full story Source: The Guardian, 31 July 2022
  5. News Article
    UK experts believe they have identified the cause of the recent spate of mysterious liver problems affecting young children around the world. Investigations suggest two common viruses made a comeback after pandemic lockdowns ended - and triggered the rare but very serious hepatitis cases. More than 1,000 children - many under the age of five - in 35 countries are thought to have been affected. Some, including 12 in the UK, have needed a lifesaving liver transplant. The two teams of researchers, from London and Glasgow, say infants exposed later than normal - because of Covid restrictions - missed out on some early immunity to an adenovirus, which normally causes colds and stomach upsets, and adeno-associated virus 2. Noah, three, who lives in Chelmsford, Essex, needed an urgent liver transplant after becoming dangerously ill with hepatitis. His mother, Rebecca Cameron-McIntosh, says the experience has been devastating. "He'd previously had nothing wrong with him," she says. "And for it to suddenly go so quickly. I think that's what kind of took us by surprise. "We've just assumed it was one little problem that will get easily sorted out - but actually it just kept on snowballing." Noah's recovery has been good - but he will need to take immunosuppressant drugs fo life, to stop his body rejecting the new liver he received. Rebecca says: "There is something really heartbreaking about that because you go along following the rules, do what you are supposed to do to protect people that are vulnerable and then, in some horrible roundabout way, your own child has become more vulnerable because you did what you were supposed to do." Read full story Source: BBC News, 26 July 2022
  6. Content Article
    The Indian Liver Patient Dataset (ILPD) is used extensively to create algorithms that predict liver disease. Given the existing research describing demographic inequities in liver disease diagnosis and management, these algorithms require scrutiny for potential biases. Isabel Straw and Honghan Wu address this overlooked issue by investigating ILPD models for sex bias. They demonstrated a sex disparity that exists in published ILPD classifiers. In practice, the higher false negative rate for females would manifest as increased rates of missed diagnosis for female patients and a consequent lack of appropriate care. Our study demonstrates that evaluating biases in the initial stages of machine learning can provide insights into inequalities in current clinical practice, reveal pathophysiological differences between the male and females, and can mitigate the digitisation of inequalities into algorithmic systems. An awareness of the potential biases of these systems is essential in preventing the digital exacerbation of healthcare inequalities.
  7. News Article
    Parents whose children have mysteriously fallen ill with hepatitis and received a delayed diagnosis could be entitled to negligence claims, lawyers believe. Officials are no closer to explaining a recent and unusual outbreak in cases of liver inflammation recorded among young children across the UK. To date, a total of 163 children have been diagnosed. Eleven of these have received liver transplants, while 13 are currently in hospital. Globally in recent months, 300 children have been struck down by the illness, which has no clear cause. Because the UK cases have been identified retrospectively, there is potential that doctors and medics may have “missed signs” which would have led to earlier hepatitis diagnoses and treatment, lawyers say. “There are a significant number of these diagnoses which are actually retrospective,” said Jonathan Peacock, a partner at VWV specialising in clinical negligence. “The obvious issue there from a negligence point of view is if you have missed signs, which ought to have led you to a diagnosis of hepatitis earlier, as a result of which it’s gone untreated and the outcome is worse, then potentially you’re negligent. “There’s two stages: was the care diagnosis, treatment, intervention, was that of a reasonable standard? If the answer is no – there was clearly a negligent delay, or a breach of duty of care, then the second question that then arises is has the individual been harmed by that delay?” Read full story Source: The Independent, 10 May 2022
  8. News Article
    UK health officials say they are still no clearer on the cause of a rise in liver inflammation, or hepatitis, in children. A common adenovirus is thought to play a role, but other possibilities are still being investigated. In the UK, 163 cases have now been identified, and 11 children have received liver transplants. Cases have been detected in 20 countries worldwide, with nearly 300 children affected, and one death. "It's important that parents know the likelihood of their child developing hepatitis is extremely low," said Dr Meera Chand, from the UK Health Security Agency (UKHSA). She said parents should still be alert to the signs - particularly jaundice, a yellow tinge in the whites of the eyes - and they should contact a doctor if concerned. Since last week, another 18 children in the UK with hepatitis have been identified - 118 live in England, 22 in Scotland, 13 in Wales and 10 in Northern Ireland. The children's most common symptoms were jaundice and vomiting - and most have been under five years old. Read full story Source: BBC News, 7 May 2022
  9. News Article
    Health officials say they are now investigating unexplained cases of hepatitis in children in four European countries and the US. Cases of hepatitis, or liver inflammation, have been reported in Denmark, Ireland, the Netherlands, Spain and the US, health officials say. Last week UK health authorities said they had detected higher than usual cases of the infection among children. The cause of the infections is not yet known. The European Centre for Disease Control (ECDC) did not specify how many cases have been found in the four European countries in total. But the World Health Organization (WHO) said less than five had been found in Ireland, and three had been found in Spain. It added that the detection of more cases in the coming days was likely. Investigations into the cause of the infections are ongoing in all of the European countries where cases have been reported, said the ECDC. In the US, Alabama's public health department said nine cases have been found in children aged one to six years old, with two needing liver transplants. Investigations into similar cases in other states are taking place, it added. Read full story Source: BBC News, 20 April 2022
  10. News Article
    Health officials are investigating 74 cases of hepatitis - or liver inflammation - in children across the UK since the start of this year. They say one potential cause of the illness could be adenoviruses, but they have not ruled out Covid-19 as a cause. Officials are examining 49 cases in England, 13 in Scotland and 12 across Wales and Northern Ireland. The UK Health Security Agency (UKHSA) said parents should be on the lookout for symptoms such as jaundice. Dr Meera Chand, director of clinical and emerging infections at UKHSA, said officials were looking at a wide range of possible factors which could be causing children to be admitted to hospital with liver inflammation. "One of the possible causes that we are investigating is that this is linked to adenovirus infection. However, we are thoroughly investigating other potential causes," she said. Other possible explanations being investigated include Covid-19, other infections or an environmental trigger. Read full story Source: BBC News, 13 April 2022
  11. News Article
    The UK Health Security Agency (UKHSA) has recently detected higher than usual rates of liver inflammation (hepatitis) in children. Similar cases are being assessed in Scotland. Hepatitis is a condition that affects the liver and may occur for a number of reasons, including several viral infections common in children. However, in the cases under investigation the common viruses that cause hepatitis have not been detected. UKHSA is working swiftly with the NHS and public health colleagues across the UK to investigate the potential cause. In England, there are approximately 60 cases under investigation in children under 10. Dr Meera Chand, Director of Clinical and Emerging Infections, said: "Investigations for a wide range of potential causes are underway, including any possible links to infectious diseases. We are working with partners to raise awareness among healthcare professionals, so that any further children who may be affected can be identified early and the appropriate tests carried out. This will also help us to build a better picture of what may be causing the cases." "We are also reminding parents to be aware of the symptoms of jaundice – including skin with a yellow tinge which is most easily seen in the whites of the eyes – and to contact a healthcare professional if they have concerns." Read full story Source: UK Health Security Agency, 6 April 2022
  12. News Article
    A surgeon who burned his initials on to the livers of two patients during transplant surgery has been struck off the medical register. Simon Bramhall, 57, admitted using an argon beam – used to stop livers bleeding during operations and to highlight an area to be worked on – to sign “SB” into his patients’ organs in 2013 while working at Birmingham’s Queen Elizabeth hospital. On Tuesday, a review by the Medical Practitioners Tribunal Service (MPTS) concluded Bramhall’s actions were “borne out of a degree of professional arrogance” and that they “undermined” public trust in the medical profession. Bramhall, of Tarrington, Herefordshire, was first suspended from his post as a consultant surgeon in 2013 after another surgeon spotted the initials during follow-up surgery on one of his patients. A photograph of the 4cm-high branding was taken on a mobile phone. During his sentencing hearing in 2018, Bramhall was told one of the victims suffered serious psychological harm as a result of the branding. The surgeon later told police he branded the organs to relieve operating theatre tensions following difficult and long transplant operations. Read full story Source: The Guardian, 11 January 2022
  13. Content Article
    Cholecystectomy is the surgical removal of the gallbladder. Cholecystectomy is a common treatment of symptomatic gallstones and other gallbladder conditions. This study from MacFadyen et al. reviewd laparoscopic cholecystectomy in the United States from 1989 to 1995. A total of 114,005 cases were analysed and 561 major bile duct injuries (0.50%) and 401 bile leaks from the cystic duct or liver bed (0.38%) were recorded. Based on this review of laparoscopic cholecystectomies, the authors found that the morbidity and mortality rates are similar to open surgery. In addition, the rate of bile duct injuries and leaks is higher than in open cholecystectomy. Furthermore, bile duct injuries can be minimised by lateral retraction of the gallbladder neck and careful dissection of Calot's triangle, the cystic duct-gallbladder junction, and the cystic duct-common bile duct junction.
  14. Content Article
    Johnathan Occleshaw is a Hepatitis C Coordinator for the North West region. In this article, on the Care, Grow, Live website, he explains how the Integrated Recovery Service in Halton micro-eliminated hepatitis C.
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