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Found 541 results
  1. News Article
    The NHS in England is struggling to make progress on its flagship target to diagnose three-quarters of cancer cases at an early stage, MPs are warning. The Health and Social Care Committee said staffing shortages and disruption from the pandemic were causing delays. Some 54% of cases are diagnosed at stages one and two, considered vital for increasing the chances of survival. By 2028, the aim is to diagnose 75% of cases in the early stages, but there has been no improvement in six years. It means England - as well as other UK nations - lag behind comparable countries such as Australia and Canada when it comes to cancer survival. If the lack of progress continues, the committee warned that it could lead to more than 340,000 people missing out on an early cancer diagnosis. The Department of Health said it recognised "business as usual is not enough" and said it was developing a new 10-year cancer plan. But a spokesman said progress was already being made, with a network of 160 new diagnostic centres being opened.R Read full story Source: BBC News, 5 April 2022
  2. News Article
    An algorithm which can predict how long a patient might spend in hospital if they’re diagnosed with bowel cancer could save the NHS millions of pounds and help patients feel better prepared. Experts from the University of Portsmouth and the Portsmouth Hospitals University NHS Trust have used artificial intelligence and data analytics to predict the length of hospital stay for bowel cancer patients, whether they will be readmitted after surgery, and their likelihood of death over a one or three-month period. The intelligent model will allow healthcare providers to design the best patient care and prioritise resources. Bowel cancer is one of the most common types of cancer diagnosed in the UK, with more than 42,000 people diagnosed every year. Professor of Intelligent Systems, Adrian Hopgood, from the University of Portsmouth, is one of the lead authors on the new paper. He said: “It is estimated that by 2035 there will be around 2.4 million new cases of bowel cancer annually worldwide. This is a staggering figure and one that can’t be ignored. We need to act now to improve patient outcomes. “This technology can give patients insight into what they’re likely to experience. They can not only be given a good indication of what their longer-term prognosis is, but also what to expect in the shorter term. “If a patient isn’t expecting to find themselves in hospital for two weeks and suddenly they are, that can be quite distressing. However, if they have a predicted length of stay, they have useful information to help them prepare. “Or indeed if a patient is given a prognosis that isn’t good or they have other illnesses, they might decide they don’t want a surgical option resulting in a long stay in hospital.” Read full story Source: University of Plymouth, 30 March 2022
  3. News Article
    An NHS trust has apologised over the death of a 27-year-old events manager after a locum gynaecologist mistook aggressive cervical cancer for a hormonal or bowel problem. The family of Porsche McGregor-Sims, who died a day after being admitted to Queen Alexandra hospital in Portsmouth, told her inquest that she had felt she was not listened to and that the misdiagnosis had robbed them of a chance to say goodbye. The area coroner Rosamund Rhodes-Kemp said the case was one of the most “shocking and traumatic” she had dealt with and she would write to Portsmouth hospitals university NHS trust expressing her concern. In December 2019, McGregor-Sims’ GP referred her to a consultant after she complained of abdominal pain and vaginal bleeding. She saw Dr Peter Schlesinger, an agency locum at the Queen Alexandra hospital, at the end of January 2020. He did not physically examine her and believed her symptoms were linked to changing hormones or irritable bowel syndrome (IBS). After the UK went into lockdown two months later, McGregor-Sims continued to report symptoms but was prescribed antibiotics over the phone and was seen in person only after a GP thought she might have Covid because she had shortness of breath. McGregor-Sims was finally diagnosed with an aggressive form of cervical cancer and on 13 April was taken to hospital, where she died a day later. During the inquest, her family accused Schlesinger of having denied them their chance to say goodbye. Her mother, Fiona Hawke, told him: “You robbed us of the opportunity to prepare for her death and say goodbye to her.” Schlesinger insisted McGregor-Sims’ symptoms – including bleeding after sex – did not lead him to think she had a serious illness. Dr Claire Burton, a consultant gynaecologist, said Schlesinger should have physically examined McGregor-Sims, and apologised for the care she received at the trust. Read full story Source: The Guardian, 24 March 2022
  4. News Article
    Patients waiting for surgery and cancer care in England will face long delays for years to come, MPs have warned in a new report that is highly critical of both ministers and NHS bosses. The already-record 6.1 million-strong waiting list for vital treatment will keep growing and officials are “too optimistic” that plans to tackle it will succeed, the public accounts committee (PAC) said in a report on Wednesday. “For the next few years it is likely that waiting time performance for cancer and elective care will remain poor and the waiting list for elective care will continue to grow,” it said. The committee of MPs, which monitors spending across Whitehall, acknowledges Covid-19’s role in contributing to the ballooning backlog and lengthening waiting times. But it singled out years of inaction by the Department of Health and Social Care (DHSC) for particular blame. Patients waiting for surgery and cancer care in England will face long delays for years to come, MPs have warned in a new report that is highly critical of both ministers and NHS bosses. The already-record 6.1 million-strong waiting list for vital treatment will keep growing and officials are “too optimistic” that plans to tackle it will succeed, the public accounts committee (PAC) said in a report on Wednesday. “For the next few years it is likely that waiting time performance for cancer and elective care will remain poor and the waiting list for elective care will continue to grow,” it said. The committee of MPs, which monitors spending across Whitehall, acknowledges Covid-19’s role in contributing to the ballooning backlog and lengthening waiting times. But it singled out years of inaction by the Department of Health and Social Care (DHSC) for particular blame. Read full story Source: The Guardian, 16 March 2022
  5. News Article
    Less than half of women are being seen following an urgent breast cancer referral, as NHS performance drops to a new low. ‘Alarming’ new NHS figures have shown just 47% of women in England referred “urgently” for breast cancer symptoms were seen by a specialist within two weeks. For women without symptoms but referred urgently to see a specialist, just 49% were seen within two weeks. In both cases this is the first time since records began that less than 50% cent of women were seen. Within some trusts less than 10% of women referred with symptoms were seen within two weeks, with less than two per cent of women referred to United Lincolnshire Hospitals Trust being seen within this time frame in January. Wes Streeting, Labour shadow health secretary said: “I know from experience the importance of an early cancer diagnosis and quick treatment. It is appalling that most suspected breast cancer patients are left waiting so long before being seen, with the insecurity of not knowing." Baroness Delyth Morgan, chief executive at Breast Cancer Now, said: “It’s alarming that in January, for the first time, less than half of women 47.5 per cent in England who were urgently referred with potential breast cancer symptoms, were seen by a specialist within two weeks." “...the government must consider what immediate steps it can take to reverse this rapid decline. Agonising delays must be replaced with prompt diagnoses for all women – and the sooner breast cancer is diagnosed the greater the chance of treatment being successful.” Read full story Source: The Independent, 11 March 2022
  6. News Article
    The two-week wait cancer target should be scrapped and replaced with a different measure, as part of an overhaul of cancer standards, NHS England has said. After piloting a new measure which aims to see 75% of patients given the all-clear or a diagnosis within 28 days of referral, NHS England has recommended .The new “faster diagnosis target” would replace the current ‘two-week wait’ target, which is for 93% to have seen a specialist within two weeks, but not necessarily had a diagnosis. This proposal, and other changes to the way cancer waiting time targets are organised, will be consulted on until 6 April. The nine current cancer targets were created in 2000. The current headline measure along with the two-week wait — a two-month wait from urgent GP referral to first treatment — has not been hit since December 2015. The document containing the proposals said the current two-week standard saw some patients given an appointment at which no test was taken, purely to hit the target. For some suspected cancers, “many trusts… offer outpatient appointments to ensure they hit the target”, without improving diagnosis. The move to scrap the two-week wait was welcomed – with significant caveats — by Cancer Research UK Cancer Research UK chief executive Michelle Mitchell said: “The new Faster Diagnosis Standard is a more meaningful target than the current two-week wait that will hopefully improve early diagnosis. If all trusts met the 75 per cent target, it would be an improvement to where we are now. However, in the long-term to improve cancer survival, we’d like to see a 95 per cent target originally proposed in the 2015 cancer strategy in Sajid Javid’s upcoming 10-year plan for cancer. “We recognise the target was set lower because of a shortage of cancer specialists, critical to diagnosing cancer across the NHS. The government must provide the extra investment they have promised to grow the NHS workforce. Every moment of delay risks more people waiting for diagnosis and treatment.” Read full story (paywalled) Source: HSJ, 10 March 2022
  7. News Article
    A Scottish hospital has become the first in the UK and one of the first in the world to pilot using artificial intelligence (AI) in its cervical cancer screening programme. University Hospital Monklands has increased capacity by around 25% and improved analysis turn-around times with the measure, which experts said could “revolutionise” the screening process. The system, from medical technology company Hologic, creates digital images of cervical smear slides from samples that have tested positive for Human Papilloma Virus (HPV). These are then reviewed using an advanced algorithm, which quickly assesses the cells in the sample and highlights the most relevant to medical experts, saving them time in identifying and analysing abnormalities. “Preliminary results from the pilot are promising, as the team at University Hospital Monklands has increased capacity by around 25 per cent in the slide assessment and improved analysis turn-around times, as well as allowing screeners to dedicate more time to training on the latest technologies and dealing with difficult-to-diagnose cases,” says Allan Wilson, consultant biomedical scientist at NHS Lanarkshire who is leading the pilot. "Through AI and digital diagnostics, we have the potential to improve outcomes for women not only in Scotland, but around the world.” Samantha Dixon, chief executive of Jo’s Cervical Cancer Trust, welcomed the pilot. “Catching cervical cell changes means they can be treated to prevent them from developing into cervical cancer,” she said. Read full story Source: The Scotsman, 4 March 2022
  8. News Article
    Stark disparities in cancer rates between different ethnic groups have been laid bare in new research showing black people are twice as likely to get prostate cancer while white people have double the chance of getting skin and lung cancers. The analysis of NHS Digital cancer registration data by Cancer Research UK provides the most complete recording ever of cancer rates by ethnicity in England, offering crucial data on how some rates vary. The results are published in the British Journal of Cancer. White people in England are more than twice as likely to get some types of cancer, including melanoma skin cancer, oesophageal, bladder and lung cancers compared with people from black, Asian or mixed ethnic backgrounds, according to the research. Black people are almost three times more likely to get myeloma and almost twice as likely to get prostate cancer compared with white people. The study also found that black people are more likely to get stomach and liver cancers, and Asian people are more likely to get liver cancers. Genetics are thought to play a part in some of the findings, Cancer Research UK said. For example, white people are more likely to get skin cancer because they tend to burn more easily in the sun. Preventable risk factors also appear to be involved, the charity added, as white people are more likely than most minority ethnic groups to smoke or be overweight or obese. These are the two largest risk factors in developing cancer and help explain why white people are more likely to get some types of cancer than other ethnic groups. Read full story Source: The Guardian, 2 March 2022
  9. News Article
    Women who have the HPV vaccine may need only one smear test to prevent cervical cancer in their lifetime, according to a leading scientist. Women are currently invited for screening every three to five years in the UK. But Prof Peter Sasieni said the vaccine was leading to such dramatic reductions in cancer that the screening programme would need to change soon. The NHS invites women, and people with a cervix, for regular screening. Swabs of the cervix are used to check for signs of abnormalities using a microscope (the traditional smear test) or more recently to test for the virus itself. However, a seismic shift in preventing cervical cancer started in the UK in 2008 with the introduction of the HPV vaccine. It is offered to girls (and boys since 2019) aged between 11 and 13. Research published in December shows the vaccine is cutting cervical cancer by nearly 90% in those who choose to have the jab. "This is really exciting," Prof Sasieni, the director of the clinical trials unit at King's College London, told Inside Health on BBC Radio 4. His modelling suggests between one and three checks a lifetime would be appropriate for people who have been immunised. "There's a new vaccine which will be used in the UK from the next school year, which protects against even more types of the virus, and I think with that probably one screen would be enough, maybe two, over a lifetime." However, the Department of Health and Social Care said one in three people do not come for screening when invited, and a spokesperson added: "The NHS Cervical Screening programme remains an important way of protecting the population - including those who have not been vaccinated - from developing cervical cancer." Read full story Source: BBC News, 2 March 2022
  10. News Article
    Breast cancer screening uptake fell to its lowest point ever during the pandemic, as the numbers of women seen dropped by more than one third. Just 1.19 million women aged 45 and over were screened for breast cancer in 2020-21, while the numbers of women who actually took up their invitation for screening dropped to 61%. Analysis by Breast Cancer Now, of the new NHS figures published on Thursday, found that uptake during the first year of the pandemic was the lowest it had been since records began. The number of women who had cancer detected through screening decreased by almost 40 per cent, although rates when calculated per 1,000 women were up by 8.4%. The news comes after NHS figures revealed that half of patients in October waited more than two weeks following an urgent breast cancer referral. According to analysis from the Labour Party in January, breast cancer patients faced the longest waits when compared to all other cancer referrals. Breast Cancer Now chief executive Baroness Delyth Morgan said: “Screening uptake has hit its lowest point in history, with less than 62% of women invited being screened, despite NHS staff working tirelessly, in the toughest of circumstances, to restart and continue breast screening services after they needed to be paused in March 2020. “The human cost behind these figures is stark, with an estimated 8,870 women in the UK living with undetected breast cancer as a result of the pandemic – a significant number of which would have been detected at routine screening. Tragically, research suggests that up to an additional 680 women could die from breast cancer in the next decade due to impacts of the pandemic on screening.” Read full story Source: The Independent, 24 February 2022
  11. News Article
    GPs and women are still ignoring key symptoms of ovarian cancer despite better awareness of the disease, a charity has warned, prompting fears that yet more patients will be diagnosed late and “die needlessly”. Symptoms include frequently having a swollen tummy or feeling bloated; pain or tenderness in the tummy or the pelvis; having no appetite or feeling full quickly after eating, and an urgent need to pee or needing to pee more often, according to the NHS. However, Target Ovarian Cancer is concerned that despite successful campaigns to boost awareness of the disease, many are still failing to act on the vital signs. “Key symptoms are being ignored – both by those experiencing them and their GPs,” a spokesperson said. A poll of 1,000 women for the charity found 79% did not know that bloating was a symptom, while 68% were unaware abdominal pain was a sign, and 97% did not know feeling full was another. Most women (99%) did not know that needing to pee more urgently was also a sign, while evidence suggests women can often be told by their GP that their symptoms are more a symptom of irritable bowel syndrome (IBS), Target Ovarian Cancer said. Ovarian cancer kills about a third of women with the disease in the first year after diagnosis, and is often diagnosed in the late stages. There are about 7,500 new ovarian cancer cases in the UK every year. “These figures are incredibly disappointing,” said Annwen Jones, the chief executive of Target Ovarian Cancer. “We know we’ve shifted the dial in the past 10 years through the dedication of thousands of Target Ovarian Cancer’s campaigners, but it is not enough. Knowing the symptoms is crucial for everyone. “We need to make sustained and large-scale government-backed symptoms campaigns a reality. Progress is possible. If we do this, fewer people will be diagnosed late, fewer will need invasive treatment, and, ultimately, fewer will die needlessly from ovarian cancer.” Read full story Source: The Guardian, 22 February 2022
  12. News Article
    Thomas Hebbron is one of the forgotten victims of the pandemic. He was diagnosed with leukaemia in February 2019 - a year before Covid hit the UK. The eight-year-old, from Leeds, has been treated with chemotherapy which has continued throughout the pandemic, but his health has suffered in other ways - and his mother believes the unrelenting focus on the virus is to blame. Pre-pandemic he was seen in person by doctors every two weeks. But that changed to monthly video calls, and liver and urinary problems went undetected. His treatment also affected his fine motor skills and has weakened his legs, but he has not seen an occupational therapist since before the pandemic. "I want to take this pain away from him," says his mother, Gemma. "I don't want to sit and watch him in this pain, but I can't do anything. I just feel completely helpless." Thomas's story is not unique. An analysis by the Nuffield Trust and Health Foundation has for the first time laid bare how access to core health services in England has been squeezed, threatening to leave behind a generation of young people. The review has looked at both physical and mental health services and come to the same conclusion - support has been badly disrupted and the plight of children overlooked. The Nuffield Trust and Health Foundation have been joined by the Royal College of Paediatrics and Child Health (RCPCH) in calling for a dedicated plan for children to help them recover from the pandemic. Dr Camilla Kingdon, RCPCH president, said the figures "do not take into account the many other 'hidden' waiting lists of children waiting for community therapies and diagnostic assessments, especially for autism". She added that children are "struggling" and, despite services being stretched, no-one should be deterred from speaking to a health professional. Read full story Source: BBC News, 18 February 2022
  13. News Article
    Thousands of men are being urged to check their risk of prostate cancer amid warnings that more than 14,000 have missed a diagnosis during the pandemic. New figures show that the disease accounts for a third of those not treated for cancer during the pandemic, making it the cancer most likely to have been missed and putting lives at risk. Experts said many men had held off visiting their GP which meant they could now be missing out on vital treatment. NHS figures suggest nearly 50,000 fewer cancer diagnoses across the UK in the Covid crisis, including 34,000 in England. Experts said prostate cancer made up the largest group of missed cases, followed by breast cancer, of which around 8,000 cases have gone undiagnosed. Prostate Cancer UK and NHS officials are urging men to use an online tool to assess their risk, with those found to be at high risk urged to then visit their GP. Read full story (paywalled) Source: The Telegraph, 17 February 2022
  14. News Article
    Thousands of people referred for urgent cancer checks every month are set to be diagnosed and treated sooner, as the NHS reforms its cancer standards to reflect what matters most to patients and to align with modern clinical practice. Developed by clinical experts and supported by leading cancer charities, there will be three cancer standards, which combine all of the previous standards and cover additional patients: the 28-Day Faster Diagnosis Standard (FDS) which means patients with suspected cancer who are referred for urgent cancer checks from a GP, screening programme or other route should be diagnosed or have cancer ruled out within 28 days. the 62-day referral to treatment standard which means patients who have been referred for suspected cancer from any source and go on to receive a diagnosis should start treatment within 62 days of their referral. the 31-day decision to treat to treatment standard which means patients who have a cancer diagnosis, and who have had a decision made on their first or subsequent treatment, should then start that treatment within 31 days. GPs will still refer people with suspected cancer in the same way, but the focus will rightly be on getting people diagnosed or cancer ruled out within 28 days, rather than simply getting a first appointment. The three agreed standards will come into effect from October. Read full story Source: NHS England, 17 August 2023
  15. News Article
    The Government must provide the health service with more support to fulfil its ambition of extending healthy life expectancy and reducing premature death, an expert has warned. It comes after the Department for Health and Social Care (DHSC) published an interim report on its Major Conditions Strategy, a 5-year blueprint to help manage six disease groups more effectively and tackle health inequality. The groups are cancer, cardiovascular disease – including stroke and diabetes – musculoskeletal conditions, chronic respiratory diseases, mental health conditions and dementia. The Government said the illnesses "account for over 60% of ill health and early death in England", while patients with two or more conditions account for about 50% of hospital admissions, outpatient visits, and primary care consultations. By 2035, two-thirds of adults over 65 are expected to be living with two or more conditions, while 17% could have four or more. Sally Gainsbury, Nuffield Trust senior policy analyst, said the Government is right to focus on the six conditions, but "will need to shift more of its focus towards primary prevention, early diagnosis, and symptom management". She added: "What's less clear is how Government will support health and care systems to do this in the context of severe pressures on staff and other resources, as well as a political culture that tends to place far more focus on what happens inside hospitals than what happens in community healthcare services, GP practices and pharmacies. This initiative is both long overdue and its emphasis has shifted over time. The Major Conditions Strategy is being developed in place of a White Paper on health inequalities originally promised over 18 months ago." Read full story Source: Medscape, 16 August 2023
  16. News Article
    Patients with cancer symptoms could bypass their GP in the future and go straight for a scan, the health secretary has suggested, in the latest “radical” attempt by the government to cut huge NHS waiting lists. The suggestion, which comes as the government is expected to reduce the number of NHS cancer waiting time targets, could form part of proposals to “design out bottlenecks” in the NHS system, Steve Barclay said in an interview. Health department officials are reportedly working on proposals that would mean some patients experiencing cancer symptoms could go straight to an NHS diagnostic centre – or “one-stop shop” – without a GP referral. “We are very much looking at those patient pathways,” Barclay told the Daily Telegraph. “Where there are bottlenecks in the system of referral from the GP, is there scope to go direct to the relevant diagnostic test or to the clinician? Breast cancer is a good example because almost always the GP refers on … and therefore there’s an opportunity to design out bottlenecks in the system.” Read full story Source: Guardian, 16 August 2023
  17. News Article
    At-home smear tests should be introduced in Wales, campaigners say. Love Your Period campaigners said self-sampling at home would encourage more people to have the tests. For women aged 25 to 64 a smear test is an effective way of detecting human papillomavirus (HPV) and preventing cervical cancer. According to Public Health Wales data, cervical cancer is the most common cancer in women under the age of 35, with regular screening helping to reduce the risk of getting cervical cancer by 70%. The Welsh government said it followed advice from the UK National Screening Committee (UKNSC), which is yet to make a recommendation on self-sampling. However, it said Public Health Wales (PHW) was considering how the tests could be implemented in Wales. Currently, women in Wales are invited for a screening to check for the presence of high-risk HPV every five years. Campaigner Jess Moultrie said tests should be made available to those who have experienced trauma and find the process of in-hospital smears triggering. "Being able to do it at home gives you that power, you can be a little bit more relaxed, it's not as intimidating." Read full story Source: BBC News, 14 August 2023
  18. News Article
    Two-thirds of NHS cancer waiting time targets are expected to be scrapped in England, in a move the health service says aims to catch cancers earlier. NHS bosses want to reduce the number of targets, most of which have been routinely missed in recent years, from nine to three. They say the plan is backed by leading cancer experts and will simplify the "outdated" standards. But some are concerned about the move. Pat Price, oncologist, visiting professor at Imperial College London and Head of the charity Radiology UK, said current performance was "shockingly bad", and while too many targets could be disruptive, "the clear and simple truth is that we are not investing enough in cancer treatment capacity". Read full story Source: BBC News, 14 August 2023
  19. News Article
    Despite regular MRI scans at the Royal Preston Hospital showing that the tumour was growing, May Ashford was not offered surgery until five years later. A woman died unnecessarily after doctors failed to operate soon enough on a growing brain tumour, according to the health complaints service. May Ashford, from Blackpool, was diagnosed with a brain tumour in 2010 after experiencing headaches and seizures. Despite regular MRI scans at the Royal Preston Hospital showing that the tumour was growing, she was not offered surgery until five years later. An investigation by the Parliamentary and Health Service Ombudsman (PHSO) said the treatment was too late as medical staff had failed to monitor the scan results properly. Medical experts said Mrs Ashford should have been operated on at least three years earlier, before the tumour had time to grow and affect the surrounding area of the brain. She tragically died aged 71 from a stroke following surgery. Link to full article here
  20. News Article
    The use of artificial intelligence in breast cancer screening is safe and can almost halve the workload of radiologists, according to the world’s most comprehensive trial of its kind. Breast cancer is the most prevalent cancer globally, according to the World Health Organization, with more than 2.3 million women developing the disease every year. Screening can improve prognosis and reduce mortality by spotting breast cancer at an earlier, more treatable stage. Preliminary results from a large study suggest AI screening is as good as two radiologists working together, does not increase false positives and almost halves the workload. The interim safety analysis results of the first randomised controlled trial of its kind involving more than 80,000 women were published in the Lancet Oncology journal. Read full story Source: Guardian 2 August 2023
  21. News Article
    The prospect of waiting at least six weeks for a biopsy was too much for Neil Perkin. In February, the 56-year-old was told that he had suspected prostate cancer which needed to be confirmed by examining a sample of his tissue. “After the initial appointment with the consultant, there were no letters, texts or anything,” Perkin said. Instead, he decided to pay for it himself: £5,000 – a substantial sum for the part-time ferry operator. The results from a private hospital in Guildford confirmed the cancer. “I’d lost faith in the NHS by this point and I went private,” he said. “The cancer was spreading and my surgeon made it clear that if I’d waited for the NHS for my prognosis, [the] chances of cancer recurrence would be far worse.” In May he paid another £22,500 for the prostate to be removed at a private hospital in London, with financial help from his family. “I feel let down. It turned out from the pathology that this was urgent and a delay would have made a huge difference to my outcome, my prognosis and quality of life. They got there in the nick of time.” Portsmouth Hospitals University Trust said it was sorry to have been unable to meet Perkin’s expectations and strived to provide quality and timely care. “But we recognise that across the NHS there is an increased demand on services and this can impact patient waiting times.” Read full story Source: The Guardian, 30 July 2023
  22. News Article
    Britain’s health regulator has partly suspended the manufacturing licence of Sciensus, a private company paid millions by the NHS to provide vital medicines, after the death of a cancer patient who was given the wrong dose of chemotherapy. The Medicines and Healthcare products Regulatory Agency (MHRA) said it had taken “immediate” action under regulation 28 of the Human Medicines Regulations 2012 law “where it appears to the MHRA that in the interests of safety the licence should be suspended”. The MHRA found “significant deficiencies” in standards at Sciensus during an investigation triggered by the death of one patient and the hospitalisation of three others. All four patients were administered “incorrect” doses of an unlicensed version of cabazitaxel, a licensed chemotherapy used to treat prostate cancer, according to people familiar with the matter. Read full story Source: The Guardian, 25 July 2023
  23. News Article
    The adoption of artificial intelligence (AI) by the NHS should be faster, and more frameworks should be in place to get emerging technologies to as many patients as possible, experts have told MPs. A number of senior figures from medicine and biotechnology gave evidence to the Health and Social Care Committee as part of its inquiry into cancer technology. Stephen Duffy, a professor of cancer screening at the Wolfson Institute of Population Health at Queen Mary University of London, told MPs there is “strong potential” for AI, particularly in areas such as reading mammograms for the breast screening programme. However, he warned that there will be “staff issues in terms of the number of staff needed to double-read mammograms”. He added: “Those issues aren’t going away. It seems to me that AI systems have already been shown to be very good in terms of detection of cancer on from mammograms, so they’re safe in that respect. Read full story Source: The Independent, 19 July 2023
  24. News Article
    A cancer patient has died and three others have been hospitalised after they were administered unlicensed versions of chemotherapy by Sciensus, a private company paid millions by the NHS to provide essential medication. Three health regulators have launched inquiries into the incident, according to people familiar with the matter. It was caused by an issue at the firm’s medicines manufacturing unit. In a statement, Sciensus confirmed an “isolated incident” had “affected four patients” and that it was “deeply saddened” that one of them had died. Sciensus offered its “sincere condolences” to the family and friends of the patient who died, and is conducting a thorough investigation, it added. The four patients received unlicensed versions of cabazitaxel, a licensed chemotherapy used to treat prostate cancer. The versions administered to the patients differed from the licensed product and therefore were considered unlicensed medicines. Sciensus is required to comply with official standards to ensure the quality of the products it produces and the protection of public health. Breaches of these standards can result in the MHRA suspending or removing a company’s licence. “Patient safety is our highest priority,” said Dr Alison Cave, the MHRA’s chief safety officer. “We are urgently investigating this issue and we will take any necessary regulatory measures to ensure patients are protected." Read full story Source: The Guardian, 7 July 2023
  25. News Article
    GPs should offer all patients presenting with signs of colorectal cancer a faecal immunochemical test (FIT) to reduce the waiting times for a colonoscopy, the National Institute for Health and Care Excellence (NICE) has recommended in draft guidance. The current NICE recommendation is to offer FIT to people presenting to primary care with low risk symptoms suggestive of colorectal cancer, while people with high risk symptoms should be immediately referred to the suspected cancer pathway. However, patients often have lengthy waiting times for colonoscopy because of limited capacity. NICE estimates that the recommendation should lead to 50% fewer referrals for urgent colonoscopies being made by GPs each year. Read full story (paywalled) Source: BMJ, 5 July 2023
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